Clinical Trial News and Research

RSS

Stem cells to repair damaged heart muscle

In the first trial of its kind in the world, 60 patients who have recently suffered a major heart attack will be injected with selected stem cells from their own bone marrow during routine coronary bypass surgery.

22 Jun 2007

Intraoperative radiation therapy for breast cancer

Princess Margaret Hospital (PMH) breast cancer specialists are using a new way to treat patients by delivering a one-time dose of radiation during surgery.

20 Jun 2007

New genome sequencing technology quickly detects rare viral mutations

Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations.

19 Jun 2007

Genzyme announces results of clinical trials of Renvela and Renagel

Genzyme Corp. has announced the results of two new studies comparing a powder form of Renvela (sevelamer carbonate) to Renagel tablets (sevelamer hydrochloride), including one trial in which patients received the powder form three times per day, and one in which it was administered once per day.

19 Jun 2007

Baxter supports better access to pandemic flu treatment in developing world

Baxter International Inc. has expressed its continued support of the World Health Organization's (WHO) pandemic planning programs through participation in a planned international stockpile program.

From Baxter International Inc. 17 Jun 2007

Folic acid supplements do not reduce risk of precancerous colon tumors

Taking folic acid supplements does not reduce the risk of developing precancerous tumors in the colon and may even increase the risk, a new study has found.

16 Jun 2007

Trial shows nanoparticle-enabled thermal therapy safe for treating cancer

Several types of metal nanoparticles are capable of converting energy, such as that carried by near-infrared light or an oscillating magnetic field, into heat at a level high enough to kill tumors.

14 Jun 2007

Newly found antibodies may be body's natural defense against Alzheimer's

In an important advance in the battle against Alzheimer's disease, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified naturally occurring antibodies in human blood that may help to defend against this form of dementia as well as other neurodegenerative diseases.

14 Jun 2007

Anticonvulsant medication gabapentin effective for fibromyalgia pain

New research supported by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) shows that the anticonvulsant medication gabapentin, which is used for certain types of seizures, can be an effective treatment for the pain and other symptoms associated with the common, often hard-to-treat chronic pain disorder, fibromyalgia.

14 Jun 2007

Priority review granted for oral formulation of HYCAMTIN (topotecan)

GlaxoSmithKline (GSK) has announced that its new drug application (NDA) for ORAL HYCAMTIN (topotecan) capsules, a treatment for relapsed small cell lung cancer (SCLC), has been granted Priority Review by the United States Food and Drug Administration (FDA).

14 Jun 2007

Eurand files NDA for Zentase for the treatment of exocrine pancreatic insufficiency

Eurand has announced that Eurand Pharmaceuticals Ltd. initiated the rolling submission of its new drug application (NDA) with the U.S. Food and Drug Administration (FDA) for Zentase for the treatment of Exocrine Pancreatic Insufficiency (EPI). Zentase (formerly EUR-1008), the company's lead product candidate, has been granted fast-track designation by the FDA.

14 Jun 2007

Eating smart, not eating less, may be the key to losing weight

Eating smart, not eating less, may be the key to losing weight. A year-long clinical trial by Penn State researchers shows that diets focusing on foods that are low in calorie density can promote healthy weight loss while helping people to control hunger.

14 Jun 2007

Study of exertion-related shortness of breath in obese men

Obese men who find themselves short of breath even after moderate physical activity are invited to participate in a study by UT Southwestern Medical Center and the Institute for Exercise and Environmental Medicine.

8 Jun 2007

Study of airway bypass treatment for emphysema

Researchers at Cedars-Sinai Medical Center announced today the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a new, minimally-invasive option for those suffering with advanced widespread emphysema.

8 Jun 2007

Low potassium levels linked to increased mortality in heart failure patients

New research from University of Alabama at Birmingham indicates that patients with heart failure who have low to low-normal serum potassium levels are at increased risk of death.

8 Jun 2007

Folic acid does not decrease the risk of benign colorectal tumors

New research indicates that folic acid supplementation does not decrease the risk of benign colorectal tumors, but may possibly increase the risk for some types of colorectal tumors, according to a study in the June 6 issue of JAMA .

8 Jun 2007

Researchers track human stem cells transplanted into rat brain

Researchers at the Stanford University School of Medicine have illuminated the path taken by human neural stem cells that were transplanted into the brains of rats and mice, and found that the cells successfully navigate toward areas damaged by stroke.

5 Jun 2007

Arsenic trioxide shows survival benefit for leukemia patients

Through participation in a government-sponsored multi-year study, researchers at the Comprehensive Cancer Center at Wake Forest University have helped confirm that arsenic trioxide ,marketed as Trisenox, significantly improves patient survival when coupled with standard chemotherapy treatment in newly diagnosed patients with acute promyelocytic leukemia, or APL.

5 Jun 2007

Study shows combination improves survival of metastatic melanoma patients

Two chemotherapy drugs combined with an agent that prevents the growth of blood vessels significantly delayed the spread of tumors in patients with metastatic melanoma, according to study findings presented at the 2007 American Association of Clinical Oncology (ASCO) Annual Meeting.

5 Jun 2007

PET accurately identifies esophageal cancer patients' positive responses to chemotherapy

Early metabolic imaging with positron emission tomography (PET) accurately identifies patients responding to chemotherapy for esophageal cancer, noted German researchers at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007