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Interim study results demonstrate anti-tumor activity of CytRx's INNO-206 in myeloma tumor cells

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced interim study results that showed its doxorubicin prodrug INNO-206 demonstrated statistically significant anti-tumor activity in human myeloma tumor cells growing in immune-deficient mice compared to a control group, while exhibiting significantly less toxicity than doxorubicin even though INNO-206 was administered at much higher doses.

3 May 2010

Curis completes enrollment in Phase I clinical trial of CUDC-101 HDAC, EGFR and HER2 inhibitor

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced that it has successfully completed enrollment and treatment of the last patient in its Phase I clinical trial of CUDC-101, Curis' first-in-class HDAC, EGFR and HER2 inhibitor.

3 May 2010

Protein test to determine response of lung cancer patients to erlotinib

Testing for the presence of specific cancer protein 'fingerprints' in the blood of lung cancer patients may be a useful means of identifying a subgroup whose tumors are more likely to shrink when treated with the drug erlotinib, especially when other testing methods are unavailable, according to new data presented at the 2nd European Lung Cancer Conference in Geneva, Switzerland.

3 May 2010

ExacTrac SV system allows precise targeting of radiotherapy using real-time X-ray images

A system that allows precise targeting of radiotherapy using real-time X-ray images has allowed French doctors to increase the dose of radiation they administered to lung and liver cancers while minimizing harm to nearby healthy tissue, researchers report at the 2nd European Lung Cancer Conference.

3 May 2010

Promising results from combination therapy of pemetrexed concurrent with radiation in lung cancer

The first trial of an important new combination therapy of treatment with the chemotherapy drug pemetrexed concurrent with radiation in lung cancer has delivered promising results, French researchers report at the 2nd European Lung Cancer Conference.

3 May 2010

BSGI improves breast cancer detection

A new study, presented at the American Society of Breast Surgeons Annual Meeting in Las Vegas, found that Breast-Specific Gamma Imaging (BSGI) is highly accurate in monitoring the response of breast cancers to neoadjuvant chemotherapy.

3 May 2010

New research suggests tumor-secreted exosomes inhibit immune response, enhance tumor metastasis

Current research suggests that tumor-secreted exosomes inhibit the immune response, enhancing tumor metastasis. The related report by Liu et al, "Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells," appears in the May 2010 issue of The American Journal of Pathology.

3 May 2010

FDA oks 'vaccine' to treat prostate cancer

Provenge, developed by Dendreon Corporation, is the first approved "treatment that uses a so-called cancer vaccine, a drug that trains the body's own immune system to fight the disease," The New York Times reports.

3 May 2010

Study indicates older women with diabetes have increase risk for colon cancer

A research team led by Mayo Clinic physicians has found that older women with diabetes face a more than doubled risk for some types of colorectal cancer.

3 May 2010

FDA approves continuation of Phase IIb clinical trial for superficial bladder cancer

Tikcro Technologies Ltd. today announced that BioCancell Therapeutics, Inc., concluded the first 18 patient group treated pursuant to a Phase IIb clinical trial of the drug candidate BC-819 for use in superficial bladder cancer. These patients had not responded to conventional treatment.

3 May 2010

Heart and liver transplant recipients at higher risk of developing lung cancer: Researchers

Heart and liver transplant recipients are at particularly high risk of developing lung cancer after receiving the donated organ, researchers report at the 2nd European Lung Cancer Conference. They are advising doctors to screen for such cancers in these patients to maximize the chance of detecting the malignancy early.

3 May 2010

Obese women more likely to have breast cancer at later stage: Study

Obese women are more likely to have breast cancer detected at a later stage and to have lymph node metastases when diagnosed than women who are not obese, according to a study presented this week at the Annual Meeting of the American Society of Breast Surgeons.

3 May 2010

McGill scientist discovers how one particular gene regulates epithelial cells

New research led by McGill Biochemist Dr. William Muller helps explain why breast-milk cells lose their structure, causing them to clump up in strange ways (photos available) and sometimes become cancer tumors. With the support of Chen Ling and Dongmei Zuo at McGill's Goodman Cancer Centre, Muller has discovered how one particular gene regulates epithelial cells - cells that normally form in sheets and are polarized to enable the transport of molecules in a single direction.

30 Apr 2010

New 4-D software program promises to improve treatment of lung cancer: Researchers

A new 4-dimensional software program promises to improve the treatment of lung cancer by allowing doctors to take the movement of breathing into account when administering radiotherapy, researchers announced today at the 2nd European Lung Cancer Conference in Geneva, Switzerland.

30 Apr 2010

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

Pieris AG announced today preclinical data for its proprietary PRS-110 Anticalin compound, which targets the c-Met receptor, demonstrating a dose-dependant reduction of tumor growth in a xenograft mouse model.

30 Apr 2010

Researchers experiment different nanoparticles that may help surgeons remove glioblastomas

Researchers have developed a way to enhance how brain tumors appear in MRI scans and during surgery, making the tumors easier for surgeons to identify and remove.

30 Apr 2010

Nationwide Children's Hospital opens first pediatric Pseudotumor Cerebri Clinic in the U.S.

While most headaches in children can be treated with over-the-counter pain medications or lifestyle changes, it is important to pay attention to their symptoms in case they herald something more serious.

30 Apr 2010

CTCA installs Calypso's real-time tumor tracking technology at Southwestern Regional Medical Center

Calypso Medical Technologies, Inc., a developer of non-ionizing real-time localization technology used for the precise tracking of tumor targets, and Cancer Treatment Centers of America, a national network of hospitals providing a comprehensive, fully integrative approach to cancer treatment, announced today that with the installation of the Calypso System at the CTCA at Southwestern Regional Medical Center in Tulsa, Okla., Calypso's real-time tumor tracking technology is now available at all CTCA centers nationwide.

30 Apr 2010

Approval of Provenge marks beginning of new era in cancer treatment: Dana-Farber Cancer Institute

Today's announcement that the U.S. Food and Drug Administration has approved Provengeâ, a new form of therapy for some prostate cancer patients, marks the beginning of an era in which patients' own immune systems become part of the standard therapeutic arsenal against cancer, say Dana-Farber Cancer Institute investigators who led a study of the treatment's effectiveness in patients.

30 Apr 2010

microRNAs serve as biomarkers for lung tumor classification: Study

Rosetta Genomics, Ltd., a leading developer and provider of microRNA-based molecular diagnostic tests, announces the publication of a study showing microRNA expression differentiates between primary lung tumors and metastases to the lung. The study, entitled, "MicroRNA expression differentiates between primary lung tumors and metastases to the lung," was published in the online edition of Pathology Research and Practice on April 28, 2010.

30 Apr 2010

Tumor News and Research

Interim study results demonstrate anti-tumor activity of CytRx's INNO-206 in myeloma tumor cells

Curis completes enrollment in Phase I clinical trial of CUDC-101 HDAC, EGFR and HER2 inhibitor

Protein test to determine response of lung cancer patients to erlotinib

ExacTrac SV system allows precise targeting of radiotherapy using real-time X-ray images

Promising results from combination therapy of pemetrexed concurrent with radiation in lung cancer

BSGI improves breast cancer detection

New research suggests tumor-secreted exosomes inhibit immune response, enhance tumor metastasis

FDA oks 'vaccine' to treat prostate cancer

Study indicates older women with diabetes have increase risk for colon cancer

FDA approves continuation of Phase IIb clinical trial for superficial bladder cancer

Heart and liver transplant recipients at higher risk of developing lung cancer: Researchers

Obese women more likely to have breast cancer at later stage: Study

McGill scientist discovers how one particular gene regulates epithelial cells

New 4-D software program promises to improve treatment of lung cancer: Researchers

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

Researchers experiment different nanoparticles that may help surgeons remove glioblastomas

Nationwide Children's Hospital opens first pediatric Pseudotumor Cerebri Clinic in the U.S.

CTCA installs Calypso's real-time tumor tracking technology at Southwestern Regional Medical Center

Approval of Provenge marks beginning of new era in cancer treatment: Dana-Farber Cancer Institute

microRNAs serve as biomarkers for lung tumor classification: Study

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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