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Key source of chronic pain appears to be an old memory trace stuck in the prefrontal cortex

Why do so many people continue to suffer from life-altering, chronic pain long after their injuries have actually healed"

5 Jun 2007

Gabapentin reduces hot flashes in men receiving androgen deprivation therapy

North Central Cancer Treatment Group ( http://ncctg/ ) researchers based at Mayo Clinic ( http://www.mayo.edu/ ) in Rochester, Minn., have discovered that low doses of a drug used to prevent epileptic seizures and to treat nerve pain caused by shingles substantially reduces hot flashes in patients who are undergoing anti-hormonal treatment, or androgen-deprivation therapy, for prostate cancer.

5 Jun 2007

Drug lapatinib shows activity against brain metastases

The drug lapatinib shrank tumors and slowed progression of brain metastases in some patients with advanced breast cancer, according to results of a clinical trial presented by Dana-Farber Cancer Institute scientists at the annual meeting of the American Society of Clinical Oncology.

5 Jun 2007

Diet may influence survival after treatment for stage III colon cancer

Patients with stage III colon cancer who have undergone surgery and chemotherapy with the goal of cure may have a higher risk of relapsing and dying early if they follow a predominantly Western diet of red meat, fatty foods, refined grains, and desserts, according to research led by investigators at Dana-Farber Cancer Institute in Boston.

5 Jun 2007

Dasatinib shows promise as first treatment for chronic myelogenous leukemia

An established second-line drug for chronic myelogenous leukemia has high response rates when given to newly diagnosed patients as their first therapy for the disease, according to early results from a Phase II clinical trial at The University of Texas M. D. Anderson Cancer Center.

5 Jun 2007

Modafinil (Provigil) alleviates post-chemotherapy fogginess

A drug described by some people as a genius pill for enhancing cognitive function provided relief to a small group of Rochester breast cancer survivors who were coping with a side effect known as chemo-brain, according to a University of Rochester Medical Center study.

5 Jun 2007

CRT and Manchester University announce biomarker alliance with AstraZeneca

Cancer Research Technology Limited (CRT), the cancer-focused development and commercialisation company, and The University of Manchester today announce the establishment of an alliance with AstraZeneca to develop serological pharmacodynamic (PD) biomarkers.

4 Jun 2007

Shark fin no benefit to cancer victims

In the latest research into the benefits of alternative therapies for cancer, shark cartilage did not help patients with lung cancer live longer but ginseng and flaxseed appeared to offer some benefit to cancer patients.

3 Jun 2007

C-reactive protein identified as marker for prostate cancer survival

Oregon Health & Science University Cancer Institute researchers have identified a protein that is a strong indicator of survival for men with advanced prostate cancer.

3 Jun 2007

New strategy for treating rare muscle disease, kidney disorders

Based on clues provided by a study with transgenic mice, a research group at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has developed a strategy that will be tested as the first treatment for people with hereditary inclusion body myopathy (HIBM), a rare, degenerative muscle disease.

3 Jun 2007

Dietary vitamin B6. B12 and folate, may decrease pancreatic cancer risk among lean people

Researchers exploring the notion that certain nutrients might protect against pancreatic cancer found that lean individuals who got most of these nutrients from food were protected against developing cancer.

3 Jun 2007

Device to treat brain cancer shows promise

New early data showed that an investigational device that specifically targets rapidly growing cancer cells with intermediate frequency electrical fields -- called Tumor-Treating Fields (TTFields) -- more than doubled the median overall survival rates in patients with recurrent glioblastoma multiforme (GBM), the most common and aggressive type of malignant brain tumor.

1 Jun 2007

FDA approves Torisel (temsirolimus) for advanced kidney cancer

The U.S. Food and Drug Administration (FDA) hasapproved Torisel (temsirolimus) for the treatment of a certain type of advanced kidney cancer known as renal cell carcinoma.

1 Jun 2007

Temsirolimus, effective new treatment for advanced renal cell carcinoma

The results of a phase III, randomized clinical study involving patients with advanced renal cell carcinoma and poor prognostic features show temsirolimus improved overall survival when compared to the current treatment for this stage of disease.

1 Jun 2007

EASE - Exhale Airway Stents for Emphysema - trial

Researchers at Cedars-Sinai Medical Center have announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a new, minimally-invasive option for those suffering with advanced widespread emphysema.

1 Jun 2007

Good news for women who choose mastectomy over lumpectomy

Radiation therapy after lumpectomy for early-stage breast cancer can be safely delivered in higher daily doses to greatly reduce treatment time.

30 May 2007

Magnetic resonance-guided, focused ultrasound surgery relieves fibroid symptoms in women

A noninvasive ultrasound procedure effectively shrinks uterine fibroids and significantly relieves fibroid-related symptoms in women, according to the results of a multicenter clinical trial reported in the June issue of the journal Radiology.

30 May 2007

Extracorporeal photopheresis may be effective in treating Crohn's disease

Results from an international multi-center Phase II clinical trial suggest that extracorporeal photopheresis (ECP) may be effective in treating patients with clinically active (OR symptomatic) Crohn?s disease who cannot tolerate or are refractory to immunosuppressants and/or anti-TNF agents.

28 May 2007

Flu vaccine patch a disappointment

A flu vaccine administered via a skin patch has produced disappointing results at a phase 1 clinical trial.

28 May 2007

Daytrana provides significant effectiveness in both boys and girls with ADHD

Shire plc has announced that DAYTRANA (methylphenidate transdermal system), its Attention Deficit Hyperactivity Disorder (ADHD) patch, had significant efficacy in reducing the symptoms of ADHD in both male and female children aged 6 to 12 years, according to clinical trial results reported at the American Psychiatric Association (APA) annual meeting in San Diego.

24 May 2007