Antigen News and Research

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Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Low-cost, non-invasive device uses light and saliva to quickly test Covid-19 patients

A team of researchers from ICFO and IrsiCaixa report on the development of a low-cost, portable, non-invasive device that uses light and saliva to test Covid-19 patients in less than 30 min.

22 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Every kind of T cell has a job to do. A healthy immune system makes sure no T cell oversteps.

22 Feb 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

Study explores the decline in viral load and immune response in COVID-19 patients

Researchers described the changes in viral ribonucleic acid the decline in viral load, and the immune response of SARS-CoV-2-infected patients, in a new preprint study.

22 Feb 2022

Widely utilized SARS-CoV-2 rapid antigen detection tests continue to perform as expected despite Omicron mutations

A recent study evaluated the performance of three at-home COVID-19 rapid antigen tests commonly used in the US against the SARS-CoV-2 Omicron variant.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Researchers evaluated the host immune responses to SARS-CoV-2 and its prolonged symptoms.

21 Feb 2022

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Researchers examined the detailed mechanisms of ‘cytokine storm’ that induces ARDS, often resulting in the death of severely ill COVID-19 patients.

21 Feb 2022

Full schedule of CoronaVac vaccine shown to be highly effective in children

A recent study on vaccine effectiveness showed that a complete primary immunization with CoronaVac effectively protects against severe coronavirus disease 2019 (COVID-19) for children and adolescents between 6 and 16 years of age – consistent with the results from phase 2 clinical trials. The paper is currently available on the Preprints with The Lancet* server while it undergoes peer review.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The emergence of the SARS-CoV-2 Delta and Omicron variants caused severe disease and hospitalizations among children and adolescents.

20 Feb 2022

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers.

18 Feb 2022

Exercise program offers psychological benefits during active surveillance for prostate cancer

In men undergoing active surveillance as an alternative to immediate treatment for prostate cancer, a supervised exercise program can reduce anxiety and fear of cancer progression, reports a study in The Journal of Urology, an Official Journal of the American Urological Association.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Antigen News and Research

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Low-cost, non-invasive device uses light and saliva to quickly test Covid-19 patients

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Study explores the decline in viral load and immune response in COVID-19 patients

Widely utilized SARS-CoV-2 rapid antigen detection tests continue to perform as expected despite Omicron mutations

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Full schedule of CoronaVac vaccine shown to be highly effective in children

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

Four times as many children hospitalized during Omicron COVID wave compared to Delta

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

Exercise program offers psychological benefits during active surveillance for prostate cancer

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

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