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Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team of researchers at the Salk Institute.

18 May 2016

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

A vaccine against one of the most dangerous hospital germs may soon be available. Scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universität Berlin have developed a substance that elicits an immune response against the gut bacterium Clostridium difficile.

13 May 2016

Synthetic heart valve one step closer to reality

The quest for a synthetic heart valve that faithfully mimics the original is a step closer to its goal with the Rice University find that a natural polymer called hyaluronan, one of the chief components of skin and connective tissue, can serve as a versatile template for growing spongiosa, the middle tissue layer in the valve's leaflets.

12 May 2016

New UHPLC columns and solvents provide advanced separation power, speed of analysis

Researchers working with complex samples can now benefit from new UHPLC columns and solvents that are designed to provide advanced separation power, speed of analysis and throughput.

From Thermo Fisher Scientific Inc. 12 May 2016

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Researchers at Tufts University have stabilized blood samples for long periods of time without refrigeration and at high temperatures by encapsulating them in air-dried silk protein.

11 May 2016

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

A promising approach for watching cell signaling processes in their physiological context: Scientists visualize apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.

11 May 2016

Osaka University researchers find way for early detection of AD

Kichitaro Nakajima, a graduate student at the Graduate School of Engineering Science, Hirotsugu Ogi, Associate Professor at the Graduate School of Engineering Science, and Yuji Goto, Professor at Institute for Protein Research, Osaka University succeeded in increasing the velocity constant for a reaction in which proteins causing Alzheimer disease (AD) turn into toxic substances to 1,000 times by using optimum frequency of ultrasonic irradiation.

11 May 2016

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors, and could significantly impact treatment management.

10 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

T cell gives precise mechanical tugs to detect friends and foes

T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.

6 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Doctors have long known that men with low testosterone are at greater risk for developing type 2 diabetes. For the first time, researchers have identified how testosterone helps men regulate blood sugar by triggering key signaling mechanisms in islets, clusters of cells within the pancreas that produce insulin. The findings, co-authored by Tulane University researchers, are published in the journal

29 Apr 2016

New study reveals increased risk of dementia in patients with rosacea

A new study has uncovered an increased risk of dementia--in particular Alzheimer's disease--in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

28 Apr 2016

Little and often gives exercise benefits in Type 2 diabetes

Sedentary, overweight adults with Type 2 diabetes can improve their cardiometabolic profile by engaging in very brief but regular periods of light walking or resistance exercise, research suggests.

28 Apr 2016

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin -- usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS, according to a new study from the Perelman School of Medicine at the University of Pennsylvania published online this month in Molecular Psychiatry in advance of the print issue.

27 Apr 2016

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

27 Apr 2016

Soy peptides, isoflavones can be more effective antimicrobial agent

Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.

26 Apr 2016

Peptides News and Research

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

Synthetic heart valve one step closer to reality

New UHPLC columns and solvents provide advanced separation power, speed of analysis

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

Osaka University researchers find way for early detection of AD

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

Scientists develop new technology that helps visualize translation of mRNA into proteins

Researchers find way to selectively deliver drugs to placenta without harming fetus

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

T cell gives precise mechanical tugs to detect friends and foes

Human milk hormones may play vital role in shaping healthy infant microbiome

Study helps discover new treatments for type 2 diabetes in men with low testosterone

New study reveals increased risk of dementia in patients with rosacea

Little and often gives exercise benefits in Type 2 diabetes

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Derivatives of female sex hormones can influence natural melanin production, study suggests

Soy peptides, isoflavones can be more effective antimicrobial agent

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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