Clinical Trial News and Research

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Potential new weight-loss wonder drug

More than 60 percent of American women are overweight, with nearly a third falling into the category of obese and at greater risk of cancer, heart disease and diabetes.

27 Sep 2007

Survey reveals ignorance and confusion about cancer amongst seniors

Barcelona, Spain: Elderly Spaniards have very poor knowledge about cancer, its causes, treatment and prevention according to research carried out amongst people living in and around Barcelona.

26 Sep 2007

fMRI helps identify early brain marker of Alzheimer's disease

Researchers using functional magnetic resonance imaging (fMRI) have found a new marker which may aid in early diagnosis of Alzheimer's disease, according to a study published in the October issue of Radiology.

26 Sep 2007

New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas

Childhood brainstem gliomas (BSGs) are rare but can be very difficult to treat successfully and they tend to have poor survival rates.

26 Sep 2007

BRCA1 gene plays significant role in non-small cell lung cancer

Barcelona, Spain: Researchers have found that the breast cancer susceptibility gene, BRCA1, plays a significant role in non-small cell lung cancer (NSCLC).

25 Sep 2007

Simple, personalized interventions improve colorectal cancer screening rates

Different types of personalized interventions can improve colorectal cancer (CRC) screening rates in primary care practices, according to a new study.

25 Sep 2007

Novel strategy to tackle acute myelogenous leukemia

A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say.

25 Sep 2007

New topical lotion safely treats nail fungus without side effects

A new topical lotion that penetrates the skin deeply enough to target and eliminate serious skin infections, but without being systemically absorbed, has shown a high degree of safety and tolerability in patients with onychomycosis, or toenail fungus, a new study has shown.

25 Sep 2007

Diet and medications may assist prevention of prostate cancer

Recent investigations of medications, diet and the molecular understanding of prostate cancer are defining potential prevention strategies for the disease, and herald a new stage in the management of this cancer, according to a new review.

25 Sep 2007

Acupuncture effective for treating low back pain

Six months of acupuncture treatment appears to be more effective than conventional therapy in treating low back pain, according to a study in the September 24 issue of Archives of Internal Medicine, although the study suggests that both sham acupuncture and traditional Chinese verum acupuncture appear to be effective in treating low back pain.

25 Sep 2007

Prana completes enrolment in phase IIa trial of PBT2 in Alzheimer's disease patients

Prana Biotechnology Limited today announced it has completed patient enrollment in its Phase IIa clinical trial of PBT2 in patients with early Alzheimer's disease.

24 Sep 2007

Past clinical trials of vitamin E fatally flawed

Generations of studies on vitamin E may be largely meaningless, scientists say, because new research has demonstrated that the levels of this micronutrient necessary to reduce oxidative stress are far higher than those that have been commonly used in clinical trials.

24 Sep 2007

AIDS Vaccine Advocacy Coalition voices disappointment in trial results for MRK-Ad5 AIDS vaccine candidate

The AIDS Vaccine Advocacy Coalition (AVAC) released the following statement from Executive Director Mitchell Warren about the announcement that vaccinations have been discontinued in the STEP Study, a test-of-concept trial of the MRK-Ad5 AIDS vaccine candidate developed by the Merck Research Laboratories.

23 Sep 2007

Diets rich in rapidly-digested carbohydrates may cause fatty liver

Diets rich in rapidly-digested carbohydrates not only expand waistlines, but may also cause fatty liver, a condition that can lead to liver failure and death, finds a new study in mice.

21 Sep 2007

Stereotactic body radiation therapy reduces length of prostate cancer treatment

Breihan Bridgewater suffers from emphysema. He sleeps on his side because when he lays flat on his back it feels like there's a boulder resting on his chest.

20 Sep 2007

Re-engineered human T cells effectively target and kill cancerous B cells

Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

18 Sep 2007

Sanofi Pasteur's new H5N1 vaccine shows promise

Sanofi pasteur, the vaccines division of sanofi-aventis Group, has announced data showing that its new investigational H5N1 pandemic influenza vaccine containing a proprietary adjuvant achieved a high immune response at the lowest dose of H5N1 antigen reported to date.

18 Sep 2007

Circulating fats kill transplanted pancreas cells

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

18 Sep 2007

Digibind offers new hopes for pre-eclampsia cure

Researchers at the University of Texas Medical Branch at Galveston are trying to determine whether a drug already available to heart patients can also be used to delay delivery in expectant mothers with severe preeclampsia.

17 Sep 2007

Evista (raloxifene hydrochloride) approved for breast cancer

The U.S. Food and Drug Administration today approved Evista (raloxifene hydrochloride) for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

17 Sep 2007