Clinical Trial News and Research

RSS

Byproduct of cholesterol metabolism blocks heart health benefits of estrogen

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

17 Sep 2007

Byproduct of cholesterol interferes with the beneficial effects of estrogen on the heart

A new study possibly offers a biological reason why hormone replacement therapy (HRT) fails to protect some postmenopausal women from heart disease.

17 Sep 2007

IMPACT: Increasing clinical trial participation

Before a new treatment for a disease like cancer becomes available, physician-researchers must recruit hundreds or thousands of patients to participate in clinical research trials.

14 Sep 2007

Phase 3 study on novel oral direct thrombin inhibitor

Boehringer Ingelheim has announced that the September 15 issue of The Lancet will publish results from the RE-NOVATE study, which investigated dabigatran etexilate as a potential therapy for patients undergoing total hip replacement surgery.

13 Sep 2007

Gallbladder removed through vagina

Surgeons at the University of California, San Diego Medical Center have performed the first clinical trial surgery in the Southwest to evaluate the safety and effectiveness of performing abdominal procedures through the body's natural openings, virtually eliminating scarring.

From Evident Corporation - Life Sciences 13 Sep 2007

Vibrating catheters break through clogged arteries

A new vibrating catheter breaks through clogged arteries like a jackhammer, obliterating total blockages in patients with dangerous chronic total occlusions (CTOs).

13 Sep 2007

GlaxoSmithKline responds to Journal of the American Medical Association articles

GlaxoSmithKline believes that conclusions drawn from the most recent meta-analyses published by Drs. Nissen et. al. and Furberg et. al. in the Journal of the American Medical Association do not confirm a difference in the safety profile of Avandia (rosiglitazone) and Actos (pioglitazone).

12 Sep 2007

Generic prostate drug finasteride helps find high-risk cancers early

Men now have another good reason to consider taking finasteride, a well-known generic drug that shrinks an enlarged prostate and reduces the risk of getting prostate cancer by 25 percent.

12 Sep 2007

Customized virus kills brain tumor stem cells that drive lethal cancer

A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.

12 Sep 2007

Link between nicotine and atherosclerosis

It's well known that smoking cigarettes increases risk for a host of serious health problems from cancer to heart disease. Now a new study from Weill Cornell Medical College in New York City looks at how they do their dirty work by contributing to atherosclerosis, or hardening of the arteries. The evidence points to nicotine, the addictive chemical in cigarettes.

11 Sep 2007

Tangerine peel extract kills certain cancer cells

Research presented at the British Pharmaceutical Conference (BPC) in Manchester, shows that a compound extracted from tangerine peel can kill certain human cancer cells.

11 Sep 2007

Most chronic sinusitis cases are from fungal-induced inflamma

Accentia Biopharmaceuticals announces evidence that most, if not all cases of chronic sinusitis (CS), are due to a fungal-induced inflammation as originally proposed by investigators at the Mayo Clinic.

11 Sep 2007

Eight things you need to know about ovarian cancer

Ovarian cancer doesn't get the kind of attention breast cancer gets. It's not as common, and because survival rates are poor, it does not produce an army of survivors to raise awareness.

11 Sep 2007

Most comprehensive recommendations related to lung cancer

New evidenced-based guidelines from the American College of Chest Physicians (ACCP) recommend against the use of low-dose computed tomography (LDCT) for the general screening of lung cancer.

11 Sep 2007

Antidepressant citalopram shows promise in treating symptoms of dementia

Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia.

11 Sep 2007

Two drugs equally effective for heart patients undergoing angioplasty

In lifesaving procedures to open blocked heart arteries a key question has persisted for years: Is use of the more expensive drug, abciximab, justified over use of the less-expensive eptifibatide

11 Sep 2007

Innovative liquid crystal technology offers promise of new drugs

A partnership between Kent State University, Summa Health System and IC-MedTech Inc. has yielded an innovative liquid crystal technology that offers the promise of new drugs which may more effectively manage cancer and other diseases.

10 Sep 2007

Laser technology detects cancer by scanning surface veins

A new technology for cancer detection that eliminates the need for drawing blood has been developed by Purdue University researchers.

5 Sep 2007

Ovation Pharmaceuticals advances development pipeline with new phase III epilepsy study

OVATION Pharmaceuticals, Inc. announced the initiation of a pivotal Phase III clinical trial evaluating clobazam, a unique 1,5 benzodiazapine with significant anticonvulsant properties, as adjunctive treatment for patients with Lennox-Gastaut syndrome (LGS), one of the most severe forms of childhood epilepsy that frequently persists into adulthood.

5 Sep 2007

Ibuprofen effective in slowing down lung disease in children with cystic fibrosis

The results of a clinical trial, published in late August in the Journal of Pediatrics, indicates that, when used as part of routine therapy, high-dose ibuprofen is safe, and effective in slowing down lung disease in children with cystic fibrosis (CF).

5 Sep 2007