Clinical Trial News and Research

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New anti-rejection medication 6-month results for heart transplant recipients to be released

New clinical trial results for heart transplant patients will be released at the upcoming International Society for Heart and Lung Transplantation (ISHLT) 27th Annual Meeting and Scientific Sessions at the Hilton San Francisco, April 25-28, 2007.

20 Apr 2007

New research may help identify patients most likely to benefit from cisplatin treatment

Researchers at the Massachusetts General Hospital (MGH) Cancer Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors.

20 Apr 2007

AstraZeneca addresses lack of ethnically diverse patients in clinical trials

To address the lack of ethnically diverse patients in clinical trials across the U.S., AstraZeneca has announced, in collaboration with the National Medical Association (NMA) and the Interamerican College of Physicians and Surgeons (ICPS), new efforts to increase ethnically diverse physician investigator participation in clinical trials.

20 Apr 2007

Viventia Biotech announces results of Proxinium antibody in combinaton with chemotherapy and radiation

Viventia Biotech has announced results of in vitro cytotoxicity and in vivo pharmacokinetic studies conducted to evaluate the potential for combining its phase III anti-cancer antibody therapeutic, Proxinium, with first-line standard of care therapy for squamous cell carcinoma of the head & neck (SCCHN).

19 Apr 2007

Protalix BioTherapeutics receives FDA approval to initiate a phase III trial of prGCD

Protalix BioTherapeutics, Inc. has announced that it has received written notice from the United States Food and Drug Administration (FDA) that it may initiate a Phase III clinical trial in the United States of its lead product candidate, prGCD, a proprietary plant cell expressed recombinant form of human Glucocerebrosidase (GCD), for the treatment of Gaucher Disease, a lysosomal storage disorder in humans.

19 Apr 2007

Placebo effect in the pharmacologic treatment of patients with lower urinary tract symptoms

All physicians involved in the treatment of PBS/IC understand that the placebo effect likely plays a major role in treatment, and is important when evaluating drug trials.

19 Apr 2007

Jefferson participates in global study to extend effectiveness of drug for Parkinson's

After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls muscle movement by replacing lost dopamine, they begin to experience motor complications that include a shortened response to each dose of L-dopa.

19 Apr 2007

Emergency contraception does not reduce unintended pregnancy rate

The morning after pill, may be a good option for individual women in crisis, but advance access to emergency contraception is no antidote for the national problem of unintended pregnancy.

19 Apr 2007

Drop in HRT use linked to decrease in breast cancer rates

According to the latest report the drop in the use of hormone replacement therapy (HRT) in mid-2002, following the results of the Women's Health Initiative study (WHI), is linked with a steep decline in new breast cancer diagnoses.

19 Apr 2007

FDA approves new Actonel dose

The U.S. Food and Drug Administration (FDA) approved a new dose for Actonel (risedronate sodium tablets) that will give patients the option of taking one Actonel 75 mg tablet on two consecutive days, for a total of two tablets monthly, to treat and prevent their postmenopausal osteoporosis.

18 Apr 2007

Review of all major studies involving anti-depressants in children

Today, the Journal of the American Medical Association (JAMA) published a review of all major studies involving anti-depressants in children and adolescents by a team of researchers from Western Psychiatric Institute in Pittsburgh.

18 Apr 2007

OncoGenex Technologies announces data from a Phase II clinical trial of OGX-011

The primary objective of this study was to assess the objective response rates (reduction in tumor size) when OGX-011 is combined with docetaxel in patients with metastatic or locally recurrent breast cancer.

18 Apr 2007

North Shore-LIJ seeks participants for liver tumor and new chemo trial

The North Shore-LIJ Health System has announced it is seeking participants for a new clinical trial that will test a new chemotherapy option for patients with liver tumors.

18 Apr 2007

Risks and benefits of antidepressant treatment for children with depression

According to a new study, conducted by the Center for Innovation in Pediatric Practice (CIPP) at Columbus Children's Hospital and published in the April 18 issue of The Journal of the American Medical Association (JAMA), there is more information for parents about the risks and benefits of antidepressant treatment for children with depression and anxiety disorders.

18 Apr 2007

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center.

18 Apr 2007

New vaccine strategy for head and neck cancers

Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer.

18 Apr 2007

Towards universal access: scaling up priority HIV/AIDS interventions in the health sector

Access to antiretroviral therapy for advanced HIV infection in low- and middle-income countries continued to grow throughout 2006, with more than 2 million people living with HIV/AIDS receiving treatment in December 2006, a 54% increase over the 1.3 million people on treatment one year earlier in these countries.

18 Apr 2007

Scientists tackle cancer with different approaches

Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.

18 Apr 2007

Tests predict outcome of antibiotic therapy for infections in persons with diabetes

Researchers from the University of Washington, Rosalind Franklin University of Medicine and Science, Merck Laboratories, and Mount Sinai School of Medicine have released a study suggesting that specific laboratory and clinical tests can predict outcome of antibiotic therapy for infections in persons with diabetes.

18 Apr 2007

Cell Genesys reports data from clinical trials of GVAX immunotherapy for prostate cancer

Evaluation of antibody responses in patients with advanced prostate cancer from these studies shows that the GVAX cell-based immunotherapy induces antibody responses to a broad array of prostate cancer- associated antigens, including some not previously known to be associated with prostate cancer.

18 Apr 2007

Clinical Trial News and Research

New anti-rejection medication 6-month results for heart transplant recipients to be released

New research may help identify patients most likely to benefit from cisplatin treatment

AstraZeneca addresses lack of ethnically diverse patients in clinical trials

Viventia Biotech announces results of Proxinium antibody in combinaton with chemotherapy and radiation

Protalix BioTherapeutics receives FDA approval to initiate a phase III trial of prGCD

Placebo effect in the pharmacologic treatment of patients with lower urinary tract symptoms

Jefferson participates in global study to extend effectiveness of drug for Parkinson's

Emergency contraception does not reduce unintended pregnancy rate

Drop in HRT use linked to decrease in breast cancer rates

FDA approves new Actonel dose

Review of all major studies involving anti-depressants in children

OncoGenex Technologies announces data from a Phase II clinical trial of OGX-011

North Shore-LIJ seeks participants for liver tumor and new chemo trial

Risks and benefits of antidepressant treatment for children with depression

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

New vaccine strategy for head and neck cancers

Towards universal access: scaling up priority HIV/AIDS interventions in the health sector

Scientists tackle cancer with different approaches

Tests predict outcome of antibiotic therapy for infections in persons with diabetes

Cell Genesys reports data from clinical trials of GVAX immunotherapy for prostate cancer

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