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Estrogen therapy may increase risk for gallbladder disease

Dominic J. Cirillo, B.S., of the University of Iowa, Iowa City, and colleagues examined data from the Women’s Health Initiative (WHI), which were two randomized, double-blind, placebo-controlled trials conducted at 40 U.S. clinical centers.

19 Jan 2005

Alvesco now available for asthma sufferers in the United Kingdom

Altana AG has announced that Alvesco (Ciclesonide), a novel inhaled corticosteroid (ICS) for the treatment of adults (18+ years) suffering from persistent asthma is now available for the first time in the United Kingdom (UK).

17 Jan 2005

Scientists are a step closer to developing drug targets to treat fungal meningitis

Scientists are a step closer to developing drug targets to treat fungal meningitis -- the infection linked to at least three deaths on Vancouver Island -- thanks to the sequencing of two Cryptococcus genomes by an international team that included researchers at the University of British Columbia and the BC Cancer Agency's Michael Smith Genome Sciences Centre in Vancouver.

17 Jan 2005

Sex hormones modulate brain damage in multiple sclerosis

Abnormalities in sex hormone levels may contribute to the damage to brain tissue typical of multiple sclerosis, indicates research in the Journal of Neurology Neurosurgery and Psychiatry.

16 Jan 2005

Soy may reduce risk of cardiovascular disease

Every 34 seconds, an American man or woman dies of cardiovascular disease. Now, research suggests that a diet rich in soybean oil can help. Two new studies shed light on the power of alpha-linolenic acid (ALA) to reduce heart disease risk. Soybean oil provides an excellent source of ALA, as do leafy greens, some nuts and flax.

12 Jan 2005

First new guidelines in more than a decade for managing asthma during pregnancy

The report reflects new medications that have emerged and updates treatment recommendations for pregnant women with asthma based on a systematic review of data on the safety of asthma medications during pregnancy. An executive summary ("Quick Reference") of the guidelines is published in the January issue of the Journal of Allergy & Clinical Immunology.

12 Jan 2005

Scientists examine the role of small sputum macrophages in the widespread disease chronic obstructive bronchitis

COPD (chronic obstructive pulmonary disease) is one of the most common fatal diseases worldwide. In Germany alone, there are about 3-5 million patients affected. COPD includes both chronic obstructive bronchitis and emphysema. Both represent irreversible changes of the central and lower respiratory tract which are accompanied by coughing, mucus production and difficulty in breathing.

10 Jan 2005

Statins lower C-reactive protein (CRP), a major new risk factor for heart disease marked by inflammation

For years, doctors have believed that statin therapy lowers the risk of heart disease solely by lowering levels of cholesterol.

9 Jan 2005

Smaller lymph nodes seen on abdominal CT scans in "healthy" people are not clinically significant

Smaller lymph nodes commonly seen on abdominal CT scans in "healthy" people are not clinically significant and require no further imaging, a new study confirms. The study was performed because there is no standard as to what should be done about these patients so they often undergo additional testing to rule out inflammation, cancer or other diseases.

9 Jan 2005

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

A major cause of pain and disability, rheumatoid arthritis (RA) is also potentially the most treatable form of chronic arthritis. Researchers, doctors, and patients agree that a group of drugs called disease-modifying antirheumatic drugs (DMARDs) can effectively reduce joint pain and stiffness.

7 Jan 2005

Strong association between high levels of hyaluronic acid and severe osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention – before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

7 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

First program to apply RNA interference (RNAi) technology to asthma

Sirna Therapeutics, Inc. has announced the first program to apply RNA interference (RNAi) technology to asthma, a highly prevalent, chronic disease accounting for an estimated $13 billion in healthcare costs in the United States, a number which is forecast to grow considerably by the end of the decade.

7 Jan 2005

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes. Statins’ effects on both complex compounds appear beneficial in cutting patients’ cardiovascular risks.

6 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe, effective therapy for geriatric patients who can't be helped by medication alone, according to new research.

3 Jan 2005

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

Inflammation News and Research

Estrogen therapy may increase risk for gallbladder disease

Alvesco now available for asthma sufferers in the United Kingdom

Scientists are a step closer to developing drug targets to treat fungal meningitis

Sex hormones modulate brain damage in multiple sclerosis

Soy may reduce risk of cardiovascular disease

First new guidelines in more than a decade for managing asthma during pregnancy

Scientists examine the role of small sputum macrophages in the widespread disease chronic obstructive bronchitis

Statins lower C-reactive protein (CRP), a major new risk factor for heart disease marked by inflammation

Smaller lymph nodes seen on abdominal CT scans in "healthy" people are not clinically significant

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

Strong association between high levels of hyaluronic acid and severe osteoarthritis

Potential cure for lymphoma in HIV patients

First program to apply RNA interference (RNAi) technology to asthma

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

New hope for millions of patients suffering from liver damage (cirrhosis)

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

Indian curry may be the next Alzheimer's weapon

Seafood research will bring healthier lifestyle

Theory that could help to cure diseases including cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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