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Novavax begins human clinical testing of novel pandemic flu vaccine

Novavax has announced that it has begun vaccinating healthy volunteers in the first human clinical trial of its virus-like particle ("VLP") based pandemic influenza vaccine.

1 Aug 2007

Active management of risk in pregnancy lowers Cesarean rates

At a time when national rates of cesarean delivery have climbed above 30%, a four-year study of patients receiving an alternative method of obstetric care experienced a significantly lower rate of cesarean births, according to a study published in the current issue of the Annals of Family Medicine .

1 Aug 2007

New TB vaccine could save over a million lives

Initial trials of a new tuberculosis (TB) vaccine mean the drug will now progress to phase II trials.

31 Jul 2007

New oral contraceptive means 365 period free days a year

Women in the United States can now access the first low-dose combination contraceptive pill which stops their periods.

31 Jul 2007

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Europe approves MIRCERA to treat anaemia

Roche has announced that the European Commission has approved its innovative drug MIRCERA to treat anaemia associated with chronic kidney disease (CKD).

27 Jul 2007

FDA statement on gene therapy trial

On July 24, 2007 the U.S. Food and Drug Administration (FDA) was informed by Targeted Genetics Corporation of Seattle about the death of a patient who received an investigational gene therapy product in a clinical trial for the treatment of active inflammatory arthritis.

27 Jul 2007

WHO announces China and India join clinical trial registry platform

The World Health Organisation (WHO) has announced the expansion of its clinical trial registry platform to include trial registers from China and India.

26 Jul 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Children with HIV early antiretroviral therapy study

Hundreds of thousands of babies around the world are born each year with HIV--more than half a million in 2006 alone.

26 Jul 2007

$Hip protectors do not reduce risk of hip fracture for nursing home residents$

Hip protectors do not reduce risk of hip fracture for nursing home residents

Use of an energy-absorbing hip protector did not provide a protective effect against hip fracture for nursing home residents, adding to increasing evidence that hip protectors, as currently designed, are not effective for preventing hip fractures, according to a study in the July 25 issue of JAMA.

25 Jul 2007

FDA advisory committee recommends that FDA wait for overall survival results from Satraplatin phase 3 trial

GPC Biotech AG has announced that the Oncologic Drugs Advisory Committee (ODAC) for the U.S. Food and Drug Administration (FDA) recommended (12-0) that the FDA should wait for the final survival analysis of the SPARC trial before deciding whether the satraplatin application is approvable for the treatment of hormone-refractory prostate cancer patients whose prior chemotherapy has failed.

25 Jul 2007

NSAIDs can reduce colorectal cancer risk

A study of Medicare patients with osteoarthritis provides additional evidence that non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin reduce the risk of colorectal cancer.

24 Jul 2007

New algorithm matches any tumor cells to best possible anti-cancer treatments

Cancer patients don't have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.

24 Jul 2007

Latest drugs improve survival for metastatic breast cancer

Newer drug therapies available since the 1990s, in particular aromatase inhibitors, improve the survival of women with metastatic breast cancer in the general population, according to a new study.

23 Jul 2007

IDM Pharma plans to amend NDA for Mifamurtide (L-MTP-PE) for the treatment of osteosarcoma

IDM Pharma, Inc. has announced that it has recently met with the U.S. Food and Drug Administration (FDA) and informed the FDA that the Company intends to take immediate action to supplement the data in its current New Drug Application (NDA) for mifamurtide (L-MTP-PE), formerly known as Junovan, which is being reviewed for the treatment of children and adolescents with non-metastatic osteosarcoma.

23 Jul 2007

EpiCept to conduct Phase III study of EpiCept NP-1 for treatment of chemotherapy induced peripheral neuropathy

EpiCept Corporation has announced that it will study EpiCept NP-1, its patented topical cream formulation of two FDA-approved drugs, 4% amitriptyline and 2% ketamine, for the treatment of chemotherapy induced peripheral neuropathy (CPN) in the ATTRACT-CPN Phase III Study (Assessment of Topical Treatment Response with Amitriptyline and Ketamine: Combination Trial in Chemotherapy Peripheral Neuropathy).

23 Jul 2007

Xenotransplantation from pigs getting closer

Experiments using pigs genetically engineered for compatibility with the human immune system have raised hopes that cross-species transplantation could soon become an option for patients with diabetes and other currently incurable diseases.

20 Jul 2007

Computers pass dosage test for thrombosis drugs

The largest ever study into the administration of blood thinning drugs like Warfarin has concluded that dosages calculated by computer are at least as safe and reliable as those provided by trained medical professionals.

From The University of Manchester 20 Jul 2007

Affiris alzheimer's vaccine in clinical trial

The Alzheimer's vaccine known as Affitope AD01 from Affiris has now entered the clinical phase of its development. All relevant regulatory and statutory approvals have been secured and this innovative treatment is now being tested on humans for the first time.

19 Jul 2007