Clinical Trial News and Research

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Silicone breast implants make a comeback in Canada

The Canadian government has reversed a partial ban placed more than 13 years ago over health concerns linked to silicone breast implants.

23 Oct 2006

Important first step towards designing new therapies for shingles

A team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), has identified a human protein that helps varicella-zoster virus, the cause of chickenpox and shingles, spread from cell to cell within the body.

20 Oct 2006

NC State researchers receive $3.5 million to tackle HIV

Researchers at North Carolina State University have received a $3.5 million grant from the National Institute of Allergy and Infectious Disease (NIAID) to develop mathematical and statistical models that will aid in designing new treatment strategies for HIV patients.

19 Oct 2006

New technique allows partial-match cell transplants for children with most resistant leukemia

Clinicians at St. Jude Children's Research Hospital have successfully demonstrated an improved technique for blood stem cell transplantations in children that shows promise for those most likely to fail standard treatment for leukemia.

16 Oct 2006

Roche asks European Medicines Agency for authorization to market Herceptin

Roche on Friday announced it has submitted an application with the European Medicines Agency to market its breast cancer drug Herceptin as a treatment for women living with an aggressive form of advanced-stage breast cancer, called HER2-positive, and hormone receptor-positive breast cancer, AFX/Forbes reports (AFX/Forbes, 10/13).

16 Oct 2006

Updates on pandemic flu vaccine trials to be presented at 44th Annual IDSA meeting

Preliminary results from clinical trials testing two different pandemic flu vaccine approaches - one a prime-boost strategy using different subtypes of H5N1 vaccines, the other an H5N1 vaccine delivered into the skin (intradermal) rather than the muscle - will be presented at the 44th Annual Meeting of the Infectious Diseases Society of America.

16 Oct 2006

New York Times examines efforts to obtain FDA approval for Abraxane to treat earlier-stage cancer

The New York Times has examined efforts by the pharmaceutical company Abraxis BioScience to obtain FDA approval for its late-stage breast cancer drug Abraxane as a treatment for earlier-stage breast cancer.

5 Oct 2006

California agency releases 10-year plan for spending $3B on embryonic stem cell research

The California Institute for Regenerative Medicine -- which is in charge of implementing the 10-year, $2.95 billion state human embryonic stem cell research program approved under Proposition 71 -- on Wednesday released a draft spending plan that "sets a strikingly modest tone" for outcomes of the research.

5 Oct 2006

Progesterone improves outcomes for victims of traumatic brain injury

A new study suggests that giving progesterone to victims with Traumatic Brain Injury (TBI) shortly following brain injury may reduce the risk of death and the degree of disability, and appears to be safe.

3 Oct 2006

Sunshine Heart awarded $2.15m grant to support development of heart assist device

Sunshine Heart, Inc., today announced it has been awarded a second Commercial Ready Grant (CRG) from the Australian Government to help fund further development of its revolutionary C-Pulse heart assist device.

21 Sep 2006

Nicotinamide may help people with multiple sclerosis

Researchers have found a possible way to protect people with multiple sclerosis (MS) from severe long-term disability: increase nervous-system levels of a vital compound, called nicotinamide adenine dinucleotide (NAD), by giving its chemical precursor - nicotinamide, a form of vitamin B3.

19 Sep 2006

MRI tracks survival of pancreatic islets after transplantation

Magnetic resonance imaging (MRI) with an approved contrast agent may provide a practical way of monitoring the survival of transplanted pancreatic islets.

12 Sep 2006

Kenya approves first clinical trial of herbal product used to treat HIV/AIDS

The Kenyatta National Hospital Ethics and Research Board recently approved the first human clinical trial in Kenya of an herbal product to treat HIV/AIDS, Kenya's Nation reports.

11 Sep 2006

Drug can quickly mobilize angiogenic cells to repair injury

To speed healing at sites of injury - such as heart muscle after a heart attack or brain tissue after a stroke - doctors would like to be able to hasten the formation of new blood vessels.

7 Sep 2006

Protein test on lung cancer cells predicts who will benefit from chemo

European researchers say a test can predict whether chemotherapy will help patients with lung cancer live longer after surgery.

7 Sep 2006

Diabetes risk down three times with newer hypertension drugs

According to researchers patients given a mix of modern blood pressure drugs are one-third less likely to develop diabetes than those on older pills.

7 Sep 2006

FDA approves limited use of artificial heart

The Food and Drug Administration (FDA) in the United States has given approval for limited use of an artificial heart.

6 Sep 2006

One of the largest Japanese cardiovascular trials confirms angiotensin receptor blockade protects people who have a wide range of cardiovascular diseases

The first controlled large-scale intervention trial of angiotensin receptor blockade in Japanese patients has confirmed that the cardiovascular protective effects of the drug valsartan is greater than to those seen with other therapies giving the same level of blood pressure control.

5 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

U.S. Army to trial of Glypromate to reduce brain injury from cardiac arrest

Neuren Pharmaceuticals today announced that physicians from Madigan Army Medical Center (Madigan) in Tacoma, Washington, will conduct an investigator- initiated Phase 2 trial to determine the safety and efficacy of Glypromate in reducing brain injury caused by out of hospital cardiac arrest.

4 Sep 2006

Clinical Trial News and Research

Silicone breast implants make a comeback in Canada

Important first step towards designing new therapies for shingles

NC State researchers receive $3.5 million to tackle HIV

New technique allows partial-match cell transplants for children with most resistant leukemia

Roche asks European Medicines Agency for authorization to market Herceptin

Updates on pandemic flu vaccine trials to be presented at 44th Annual IDSA meeting

New York Times examines efforts to obtain FDA approval for Abraxane to treat earlier-stage cancer

California agency releases 10-year plan for spending $3B on embryonic stem cell research

Progesterone improves outcomes for victims of traumatic brain injury

Sunshine Heart awarded $2.15m grant to support development of heart assist device

Nicotinamide may help people with multiple sclerosis

MRI tracks survival of pancreatic islets after transplantation

Kenya approves first clinical trial of herbal product used to treat HIV/AIDS

Drug can quickly mobilize angiogenic cells to repair injury

Protein test on lung cancer cells predicts who will benefit from chemo

Diabetes risk down three times with newer hypertension drugs

FDA approves limited use of artificial heart

One of the largest Japanese cardiovascular trials confirms angiotensin receptor blockade protects people who have a wide range of cardiovascular diseases

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

U.S. Army to trial of Glypromate to reduce brain injury from cardiac arrest

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