Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Australian researchers make a quantum leap in understanding key cell structures

Researchers in Australia and the UK have made a world first discovery that will provide the most accurate understanding to date of the structure and function of the most important energy converting protein, critical to the function of all organs and a cause of disease when malfunctioning.

20 Oct 2011

Sam Houston State receives NIJ/FSF grant to investigate BKA designer drugs

In October 2011 the National Institute of Justice (NIJ) and the Forensic Science Foundation (FSF) funded a capstone project proposal in the Master of Forensic Science Program at Sam Houston State University to investigate the designer drugs known as "Bath Salts."

19 Oct 2011

Mass spectrometry reveals precise spatial distribution of drug within tissue

When a new drug is developed, the manufacturer must be able to show that it reaches its intended goal in the body's tissue, and only that goal. Such studies could be made easier with a new method now established at Lund University in Sweden.

18 Oct 2011

IRMS tracks course of designer 'legal high' drugs manufacture

Urgently needed tests which could help identify the manufacturers of designer 'legal high' drugs are being developed in research led at the University of Strathclyde in Glasgow.

14 Oct 2011

Bruker launches SHS-40 Automated Headspace Sampler

At the analytica AnaCon India conference in Mumbai, India, Bruker today announced the release of its newly developed SHS-40 Automated Headspace Sampler.

12 Oct 2011

Novel binding assay can simplify search for potential SERT inhibitors

Many psychiatric conditions are caused by aberrant metabolism of the neurotransmitter serotonin. Researchers in the Department of Pharmacy at LMU have now developed a new screening method, which will facilitate the search for new drugs that modulate the biological activity of serotonin.

1 Oct 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

Yale researchers use AB SCIEX's QTRAP technology to synthesize phosphoproteins

AB SCIEX, a global leader in life science analytical technologies, today announced that Yale University researchers used QTRAP technology to prove the validity of a new approach to synthesize phosphoproteins.

28 Sep 2011

CoPlex, Hawthorn sign license agreement for hawAD14 Alzheimer's drug

CoPlex Therapeutics has signed an exclusive global license agreement with Hawthorn Pharmaceuticals to develop and commercialize hawAD14, a preclinical oral small molecule candidate for the treatment of Alzheimer's and other neurodegenerative diseases.

23 Sep 2011

World's first permanent food safety lab opens

The U.S. Food and Drug Administration, University of Maryland, their Joint Institute for Food Safety and Applied Nutrition and Waters Corporation today opened the International Food Safety Training Laboratory, a groundbreaking public-private partnership that applies government, university and private industry expertise and resources to the global food safety challenge.

15 Sep 2011

Innovative UMD-based food safety program to launch on Sept. 15

Amid ongoing concerns about E. coli, Salmonella and other food-borne illnesses, a new facility will take a unique approach to make imports bound for the United States safer: Give foreign technicians who test those foods intensive, hands-on lab training in U.S. government methods, standards and technology, as well as acceptable alternatives.

8 Sep 2011

Study: Protein's structural arrangement can change its signaling function

In a joint study, scientists from the California and Florida campuses of The Scripps Research Institute have shown that changes in a protein's structure can change its signaling function and they have pinpointed the precise regions where those changes take place.

8 Sep 2011

Waters launches new single quadrupole mass detector at 2011 JAIMA Expo

Waters Corporation today introduced the Waters® SQ Detector 2, a new single quadrupole mass detector, at the 2011 JAIMA Expo.

6 Sep 2011

Bruker releases new amaZon speed ion trap mass spectrometers

At the HUPO 10th Annual World Congress in Geneva, Switzerland, and at the JAIMA Conference in Tokyo, Japan, Bruker this week announces the release of its new high-performance amaZon speed and amaZon speed ETD ion trap mass spectrometers (ITMS) to meet the increasing demands of the proteomics, research and applied markets.

6 Sep 2011

Inhibiting the ability of immune cells to use fatty acids slows MS progression

In a paper published today in the journal Scientific Reports, a pair of researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis.

3 Sep 2011

Researchers identify molecule that can stop the formation of amyloid fibrils

A molecule which can stop the formation of long protein strands, known as amyloid fibrils, that cause joint pain in kidney dialysis patients has been identified by researchers at the University of Leeds.

29 Aug 2011

Hutchinson Center to participate in NCI-funded proteome research consortium

The National Cancer Institute today announced that a team co-led by Fred Hutchinson Cancer Research Center and The Broad Institute in Cambridge, Mass., has been selected to participate in a National Cancer Institute-funded research consortium dedicated to understanding the molecular basis of cancer.

23 Aug 2011

Scientists uncover how human egg captures sperm to begin fertilisation process

Researchers have uncovered exactly how a human egg captures an incoming sperm to begin the fertilisation process, in a new study published this week in the journal Science.

19 Aug 2011

Bruker second quarter revenue increases 33% y-o-y to $401.2 million

Bruker Corporation today reported financial results for the three and six months ended June 30, 2011.

3 Aug 2011

New approach to overcome complexities of developing more effective drugs for treating diseases

Pharmaceutical scientists typically face a meager five percent success rate for anti-cancer drugs in clinical trials. To help improve this success rate, Japanese scientists, led by Dr. Tetsuya Terasaki, one of the top pharmaceutical scientists focused on drug transporters, have developed a new approach designed to overcome complexities of developing new, more effective drugs to treat diseases, including cancer.

3 Aug 2011