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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers identify tumor-suppressing genes to diagnose the phase of laryngeal cancer

Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards.

8 Oct 2009

Family and population based approaches sheds new light on the potential roles of common and rare forms of human genetic variation

In one of the first studies of its kind, an international team of researchers has uncovered a single-letter change in the genetic code that is associated with autism. The finding, published in the October 8 issue of the journal Nature, implicates a neuronal gene not previously tied to the disorder and more broadly, underscores a role for common DNA variation.

8 Oct 2009

NCI awards $11.5 million grant to UAB for cervical cancer research

The University of Alabama at Birmingham (UAB) Comprehensive Cancer Center has won an $11.5 million grant from the National Cancer Institute (NCI) to explore groundbreaking cervical cancer research, prevention and treatment.

8 Oct 2009

New apoptosis detection kit for monitoring chromatin condensation

Enzo Biochem, Inc.’s Enzo Life Sciences division today announced the addition of a new apoptosis detection kit for monitoring chromatin condensation to its rapidly expanding CELLestial™ product line for live cell analysis.

7 Oct 2009

NHGRI awards Geospiza a SBIR grant to develop software systems for detecting rare mutations

Geospiza, Inc., the market leading developer of genetic analysis software, today announced the receipt of a Phase I SBIR grant for “Software Systems for Detecting Rare Mutations” from the National Human Genome Research Institute (1R43HG005297-01).

7 Oct 2009

Idera Pharmaceuticals commences phase 1 IMO-2125 clinical trial for chronic HCV infection

Idera Pharmaceuticals, Inc. today announced that patient treatment has been initiated in a phase 1 clinical trial evaluating IMO-2125 in combination with ribavirin in treatment-naive patients with chronic hepatitis C virus (HCV) infection. IMO-2125 is a novel agonist of Toll-like Receptor (TLR) 9.

7 Oct 2009

Research study to determine association of CYP2D6 variation with tamoxifen therapy

Among women with early stage breast cancer, genetic variation of a certain enzyme appears to be associated with clinical outcomes for women treated with tamoxifen, according to a study in the October 7 issue of JAMA.

7 Oct 2009

Study reveals large structural differences between natural prions and man-made synthetic analogs

A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions and the closest synthetic analogs that scientists have created in the lab.

7 Oct 2009

Scientists develop new molecule that can deliver genetic-based drugs into cells

Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati have developed a new molecule that can travel into cells, deliver genetic cargo, and packs a beacon so scientists can follow its movements in living systems.

7 Oct 2009

Call for new policies on access to biobanked children's DNA

Scientists look for clues about therapies and cures for life-threatening childhood illnesses in children's DNA -- it seems only logical to do so. But the decision as to who should have access to DNA samples from children provides a unique ethical conundrum, says a Tel Aviv University researcher in a recent publication for the esteemed journal Science, co-authored by colleagues from The Netherlands and Canada.

7 Oct 2009

Clinical Genomics extends collaboration with CSIRO

Sydney-based Clinical Genomics Pty Ltd and CSIRO have entered into a new phase in their collaboration to develop improved diagnostics for cancers of the colon and rectum (bowel cancer).

7 Oct 2009

Researchers show that DNA methylation plays a crucial role for cancer stem cells

During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation.

7 Oct 2009

AOAC Research Institute certifies Idaho's E.coli O157:H7 test

Idaho Technology, Inc. (ITI) has been granted Performance Tested Methods Status by the AOAC Research Institute (Certificate No. 100901) for its E.coli O157:H7 test used with the R.A.P.I.D.® LT Food Security System (FSS). The assay uses real-time PCR technology to identify the presence of E.coli O157:H7 in raw ground beef and uncooked spinach food samples.

7 Oct 2009

Gene mutation linked to age-related hearing loss

Patients who exhibited a certain genetic mutation of anti-oxidant enzymes are three times more likely to develop age-related hearing loss (ARHL), according to new research presented at the 2009 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in San Diego, CA.

7 Oct 2009

Researchers make breakthrough in finding a vaccine against horse disease strangle

A research group at the Department of Microbiology, Swedish University of Agricultural Sciences (SLU) in Uppsala, Sweden has - in collaboration with J-I Flock's research group at the Karolinska Institutet medical university in Stockholm, the pharmacological company Intervacc AB, Stockholm and the Animal Health Trust in the UK - after many years of research made a breakthrough in finding a vaccine against the horse disease strangle.

7 Oct 2009

Scientists expand their fleet of genomic next-generation sequencing technology to study about cancer

Scientists from the Baylor College of Medicine Human Genome Sequencing Center (HGSC) are expanding their fleet of advanced genomic next-generation sequencing technology from Applied Biosystems, part of Life Technologies Corporation to accelerate their studies of the genetic underpinnings of cancer and other complex human diseases.

6 Oct 2009

Hepatitis B Foundation calls for consistent monitoring and referral of HBV infected children

An expert panel of nationally recognized pediatric liver specialists convened by the Hepatitis B Foundation is calling for more consistent monitoring and referral of children chronically infected with the hepatitis B virus (HBV). The panel's recommendations for pediatricians and other primary care practitioners stress the need for routine monitoring of children with chronic HBV infections, and timely consultation with a pediatric liver specialist.

6 Oct 2009

Study reveals information about molecular structure of prions

6 Oct 2009

Researchers identify that KLF17 gene with Id1 gene can regulate breast cancer metastasis

Researchers at The Wistar Institute have identified a key gene (KLF17) involved in the spread of breast cancer throughout the body. They also demonstrated that expression of KLF17 together with another gene (Id1) known to regulate breast cancer metastasis accurately predicts whether the disease will spread to the lymph nodes.

6 Oct 2009

Two-thirds of tonsil tumour samples show evidence of HPV-16 gene: Study

It is estimated that more than 7,000 people are diagnosed with head and neck cancer each year in the UK and approximately 3,500 cases result in death. These cancers include tumours of the mouth, lips, throat and voice-box, and some have been linked to the sexually transmitted infection, HPV-16. Scientists at Liverpool analysed the DNA of more than 90 cancerous tissue samples to look for genes that indicated infection.

6 Oct 2009

DNA News and Research

Further Reading

Researchers identify tumor-suppressing genes to diagnose the phase of laryngeal cancer

Family and population based approaches sheds new light on the potential roles of common and rare forms of human genetic variation

NCI awards $11.5 million grant to UAB for cervical cancer research

New apoptosis detection kit for monitoring chromatin condensation

NHGRI awards Geospiza a SBIR grant to develop software systems for detecting rare mutations

Idera Pharmaceuticals commences phase 1 IMO-2125 clinical trial for chronic HCV infection

Research study to determine association of CYP2D6 variation with tamoxifen therapy

Study reveals large structural differences between natural prions and man-made synthetic analogs

Scientists develop new molecule that can deliver genetic-based drugs into cells

Call for new policies on access to biobanked children's DNA

Clinical Genomics extends collaboration with CSIRO

Researchers show that DNA methylation plays a crucial role for cancer stem cells

AOAC Research Institute certifies Idaho's E.coli O157:H7 test

Gene mutation linked to age-related hearing loss

Researchers make breakthrough in finding a vaccine against horse disease strangle

Scientists expand their fleet of genomic next-generation sequencing technology to study about cancer

Hepatitis B Foundation calls for consistent monitoring and referral of HBV infected children

Study reveals information about molecular structure of prions

Researchers identify that KLF17 gene with Id1 gene can regulate breast cancer metastasis

Two-thirds of tonsil tumour samples show evidence of HPV-16 gene: Study

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