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Micro RNA plays a key role in melanoma metastasis

Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly.

9 Feb 2009

Anti-HIV vaginal gel shows promise

An investigational vaginal gel intended to prevent HIV infection in women has demonstrated encouraging signs of success in a clinical trial conducted in Africa and the United States.

9 Feb 2009

New understanding of blinding degenerative eye conditions

Though based on mouse studies, the research bolsters the idea that humans suffering from these and other eye conditions may be able to help preserve function by adding antioxidants to their diet, and explains why this would work.

8 Feb 2009

Healthcare reform

Faced with a barrage of pressing issues, the Obama administration has placed health-care reform high on its agenda.

8 Feb 2009

Medicines sold in Sweden cause serious environmental harm in India

Many of the substances in our most common medicines are manufactured in India and China.

8 Feb 2009

New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease

The inactivity or "silence" of certain genes plays a fundamental role in the prognosis of acute lymphoblastic leukemia as well as in response to treatment, according to the results of research involving a team made up of specialists from the University Hospital of Navarra and the Center for Applied Medical Research at the same University of Navarra, as well as the Reina Sofía Hospital in Cordoba, Andalusia.

8 Feb 2009

Idenix Pharmaceuticals and GSK sign agreement for novel NNRTI for treatment of HIV

Idenix Pharmaceuticals, Inc. and GlaxoSmithKline (GSK) today announced the execution of a license agreement granting GSK exclusive worldwide rights to IDX899.

8 Feb 2009

Cognitive training can alter the biochemistry of the brain

Researchers at the Swedish medical university Karolinska Institutet have shown for the first time that the active training of the working memory brings about visible changes in the number of dopamine receptors in the human brain.

8 Feb 2009

New research may lead to new pharmacologic approaches to treating obesity

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.

5 Feb 2009

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

What's the ideal relationship between the drug industry, health professionals and patients?

The relationship between the drug industry, academia, healthcare professionals, and patients is widely believed to be at an all time low.

3 Feb 2009

Major malaria breakthrough

A team of Monash University researchers led by Professor James Whisstock has made a major breakthrough in the international fight against malaria, which claims the life of a child across the world every 30 seconds.

3 Feb 2009

Robot scientist promises to dig up new drugs

A robot scientist that can make informed guesses about how effective different chemical compounds will be at fighting different diseases could revolutionise the pharmaceutical industry by developing more effective treatments more cheaply and quickly than current methods.

3 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Recent reports regarding mercury and high fructose

ChemRisk, a leading scientific consulting firm, was asked by the Corn Refiners Association (CRA) to examine the recent publication by Institute for Agriculture and Trade Policy (IATP), "Not So Sweet: Missing Mercury and High Fructose Corn Syrup," and the Environmental Health journal publication "Mercury from chlor-alkali plants: measured concentrations in food product sugar," by Dufault et al, 2009, and to offer our comments and analysis.

2 Feb 2009

New CDC study assesses impact of genetic testing on health outcomes

Some genomic tests developed to personalize medical decisions about cancer care are beneficial, while for others the evidence is uncertain and reliance on the test might even lead to poorer medical management of cancer in some cases, according new recommendation statements from an expert panel.

2 Feb 2009

Internet program helps reduce depressive symptoms in teens

An Internet program helps to reduce depressive symptoms and prevent episodes of clinical depression in adolescent patients at risk, reports a study in the February issue of the Journal of Developmental & Behavioral Pediatrics.

2 Feb 2009

New compound shows potential as tuberculosis drug

Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks.

2 Feb 2009

New imaging technique catches arthritis early

You come into a doctor's office with severe knee pain. The physician orders an MRI, which reveals substantial loss of cartilage - osteoarthritis, that is - in your knee joint. At this point, not much can be done beyond gulping down palliatives and trying to keep your weight off the joint. But the damage may have started building as much as 20 years earlier, possibly due to a traumatic injury to the affected joint.

29 Jan 2009

Research finds more than 100 gene variations linked with response to leukemia treatment

Scientists from St. Jude Children's Research Hospital and the Children's Oncology Group (COG) have discovered in children with acute lymphoblastic leukemia (ALL) scores of inherited genetic variations that clinicians might be able to use as guideposts for designing more effective chemotherapy for this cancer.

29 Jan 2009