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G-CSF therapy does not induce chromosomal instability in healthy stem cell donors

According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug that releases stem cells from the bone marrow into the blood, is unlikely to put healthy stem cell donors at risk for later development of abnormalities involving loss or gains of chromosomes that have been linked to hematologic disorders such as myelodysplastic syndromes (MDS) and acute myeloid leukemia.

12 Aug 2011

Radiofrequency ablation safe and effective for treatment of dysplastic Barrett's esophagus

Radiofrequency ablation (RFA) is a safe and effective option for the treatment of dysplastic Barrett's esophagus that attains lasting response, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Progression of disease, which can precede cancer, was rare in patients who underwent RFA treatment, and there was no procedure- or cancer-related mortality.

12 Aug 2011

Pacira second quarter total revenues increase to $3.6 million

Pacira Pharmaceuticals, Inc., an emerging specialty pharmaceutical company, today announced financial results for the second quarter ended June 30, 2011, provided an update on the execution of its pre-commercial and launch strategies for EXPAREL, and updated its 2011 financial guidance.

11 Aug 2011

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division.

11 Aug 2011

FUS Foundation awards $112,002 grant to Harvard brain researcher

The Focused Ultrasound Surgery Foundation has announced its latest Research Award recipient is Nathan McDannold, Ph.D. The $112,002 award will support McDannold's efforts to increase the regions in the brain that can be safely targeted by MR-guided focused ultrasound, an innovative, noninvasive medical technology being championed by the Foundation.

11 Aug 2011

New treatment uses lasers to stimulate stem cells and reduce heart scarring

After a heart attack or stroke, heart scarring can lead to dangerously paper-thin heart walls and a decreased ability to pump blood through the body. Although the heart is unable to completely heal itself, a new treatment developed at Tel Aviv University uses laser-treated bone marrow stem cells to help restore heart function and health.

11 Aug 2011

Study suggests link between gene variant and Proteus syndrome

Orthopaedic surgeons from Children's National Medical Center are part of a team of researchers that has identified the genetic mutation causing Proteus syndrome, a rare disorder in which tissue and bone grow massively out of proportion.

11 Aug 2011

Researchers helps explain how the adult brain cleans out dead brain cells and produces new ones

Adult brains generate thousands of new brain cells called neurons each day; however only a small fraction of them survive. The rest die and are consumed by scavenger cells called phagocytes. Until now, scientists have not fully understood how this process works, which phagocytes are unique in the brain, and how the removal of dead neurons influences the production of new neurons.

10 Aug 2011

Biomarker may signal whether common back pain treatment will work

A new study from researchers at the Stanford University School of Medicine has identified a unique protein complex that can be used to predict whether an epidural steroid injection will help relieve pain caused by a herniated disc in the lower spine.

10 Aug 2011

NCI, Genesis Biopharma sign CRADA agreement to develop cancer immunotherapies

Genesis Biopharma, Inc., a biotechnology company developing targeted cancer immunotherapies, today announced it has signed a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute.

10 Aug 2011

Pre-operative education programme can reduce hospital stay for knee replacement patients

Potential to reduce NHS costs while offering more effective rehabilitation for knee replacement patients has been identified following a 20 month study carried out by academics at Northumbria University in conjunction with Gateshead Health NHS Foundation Trust.

10 Aug 2011

House Dem supports lawsuit against Medicare regarding physician pay

The action, which is being brought by the Center for Primary Care in Georgia, takes issue with the way Medicare sets its reimbursement rates for specialists and primary care physicians.

10 Aug 2011

Transaxillary thyroid robotic surgery removes nodules with no visible scar

As the rate of thyroid cancer continues to climb, doctors are urging patients to be more cautious about thyroid nodules, a common disorder that is responsible for a small but growing number of thyroid cancer cases.

10 Aug 2011

Young blacks with kidney disease more likely to die on dialysis than whites

For years, medical studies have reached the same conclusion: African-American patients do better on kidney dialysis than their white counterparts. But new Johns Hopkins research, published in the Journal of the American Medical Association, shows that younger blacks - those under the age of 50 - actually do much worse on dialysis than equally sick whites who undergo the same blood-filtering process.

10 Aug 2011

BIDMC researchers receive PCF Challenge Awards for novel prostate cancer study

Beth Israel Deaconess Medical Center (BIDMC) researchers Martin Sanda, MD, and Steven Balk MD, PhD, have been awarded Challenge Awards of $1 million each from the Prostate Cancer Foundation (PCF) to lead two cross-disciplinary teams of investigators in their pursuit of new treatments for patients with advanced prostate cancer.

10 Aug 2011

Erythromycin can prevent and treat aseptic loosening of total joint replacement

Total joint replacement surgeries can help relieve joint pain common in people with conditions like osteoarthritis. But sometimes, the debris from prosthetic joints leads to aseptic loosening, or disintegration of surrounding bones.

10 Aug 2011

Nearly half of men expect better recovery from side-effects of prostate cancer surgery

Nearly half of men undergoing surgery for prostate cancer expect better recovery from the side effects of the surgery than they actually attain one year after the operation, a University of Michigan Comprehensive Cancer Center study finds.

10 Aug 2011

Health Canada approves Boston Scientific's WallFlex Biliary RX Fully Covered Stent

Boston Scientific Corporation's WallFlex Biliary RX Fully Covered Stent has received Health Canada approval for the treatment of benign biliary strictures, which supplements its current indication for management of malignant biliary strictures.

10 Aug 2011

Toilet training for young children

Parents often ask their doctors for advice on toilet training young children, and a new article in CMAJ summarizes current approaches and evidence to help physicians respond to these queries.

9 Aug 2011

Acute Care Emergency Surgical Service linked with 15% reduction in decision time

The use of Acute Care Emergency Surgical Service (ACCESS) in emergency departments (EDs) can lead to significant reductions in key patient measures, such as length of stay, surgical decision-making time and "time-to-stretcher", according to a study published in the August issue of the Journal of the American College of Surgeons.

9 Aug 2011

Surgery News and Research

G-CSF therapy does not induce chromosomal instability in healthy stem cell donors

Radiofrequency ablation safe and effective for treatment of dysplastic Barrett's esophagus

Pacira second quarter total revenues increase to $3.6 million

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

FUS Foundation awards $112,002 grant to Harvard brain researcher

New treatment uses lasers to stimulate stem cells and reduce heart scarring

Study suggests link between gene variant and Proteus syndrome

Researchers helps explain how the adult brain cleans out dead brain cells and produces new ones

Biomarker may signal whether common back pain treatment will work

NCI, Genesis Biopharma sign CRADA agreement to develop cancer immunotherapies

Pre-operative education programme can reduce hospital stay for knee replacement patients

House Dem supports lawsuit against Medicare regarding physician pay

Transaxillary thyroid robotic surgery removes nodules with no visible scar

Young blacks with kidney disease more likely to die on dialysis than whites

BIDMC researchers receive PCF Challenge Awards for novel prostate cancer study

Erythromycin can prevent and treat aseptic loosening of total joint replacement

Nearly half of men expect better recovery from side-effects of prostate cancer surgery

Health Canada approves Boston Scientific's WallFlex Biliary RX Fully Covered Stent

Toilet training for young children

Acute Care Emergency Surgical Service linked with 15% reduction in decision time

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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