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ASTRO and ACR release practice guidelines for new radiation treatments

The American Society for Radiation Oncology (ASTRO) and the American College of Radiology (ACR) have released practice guidelines for image guided radiation therapy (IGRT) and stereotactic body radiation therapy (SBRT) in the February issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO.

4 Feb 2010

BioMarin Pharmaceutical signs stock purchase agreement to acquire LEAD Therapeutics

BioMarin Pharmaceutical Inc. announced today that it has entered into a stock purchase agreement to acquire LEAD Therapeutics, Inc. (LEAD), a small private drug discovery and early stage development company with key compound LT-673, an orally available poly (ADP-ribose) polymerase (PARP) inhibitor for the treatment of patients with rare, genetically defined cancers.

4 Feb 2010

Study on the role of MCP-1 in obese patients with pancreatic cancer

The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to research conducted by scientists at the Jefferson Pancreatic, Biliary and Related Cancers Center. They presented their data at the 5th Annual Academic Surgical Congress, held in San Antonio.

4 Feb 2010

Researchers uncover new mechanism to protect individuals from serious complications of obesity

Although obesity is a risk factor for diabetes and coronary heart disease worldwide, only some obese individuals go on to develop these metabolic complications, while others are relatively protected. Defining these protective factors could help scientists prevent disease in the wider population.

4 Feb 2010

Anti-inflammatory plant derivative could play a role in cancer treatment, say MCG researchers

Medical College of Georgia researchers are seeking to refine cancer treatment with an anti-inflammatory plant derivative long used in Chinese medicine.

4 Feb 2010

Brentuximab vedotin-chemotherapy combination clinical trial for Hodgkin lymphoma announced

Seattle Genetics, Inc. and Millennium Pharmaceuticals, Inc.: The Takeda Oncology Company today announced that they have initiated a phase I clinical trial of brentuximab vedotin (SGN-35) in combination with chemotherapy for the treatment of newly diagnosed Hodgkin lymphoma patients. Brentuximab vedotin is an antibody-drug conjugate (ADC) that is also in single-agent clinical trials, including a pivotal trial for relapsed and refractory Hodgkin lymphoma and a phase II trial for systemic anaplastic large cell lymphoma.

4 Feb 2010

Iodoprovidone exhibits safety and efficiency in management of malignant pleural effusion

In the USA each year, 200,000 cancer patients suffer from a malignant pleural effusion - development of excessive fluid (pleural effusion) in the chest. Several litres of such fluid can accumulate, and many patients suffer from significant breathlessness and distress. One in four patients with lung cancer, one in every three with breast cancer and most of the patients with mesothelioma will develop a malignant effusion.

3 Feb 2010

TGen, Horizon Discovery partner in development of novel cancer cell-lines

The Translational Genomics Research Institute (TGen) and Horizon Discovery today announced plans to develop human disease models for use in TGen's cancer research.

3 Feb 2010

Baker's yeast promising against cancer

A researcher at Charles Drew University of Medicine and Science is investigating the potential use of non-pathogenic baker's yeast as a promising, natural therapy for cancer.

3 Feb 2010

News article on the evolving role of hyperthermia in cancer therapy

BSD Medical Corp. reports publication of a news article by the Journal of the National Cancer Institute on the evolving role of hyperthermia in cancer therapy titled, “International Study of Hyperthermia Spurs Hope in U.S.” (J. Natl. Cancer Inst. 2010 102: 79-81; doi:10.1093/jnci/djp530).

3 Feb 2010

10 new kits available for fast and simple isolation of nucleic acids from blood, plasma and serum

Norgen Biotek Corp., an innovative privately held Canadian biotechnology company focusing primarily on advancing powerful tools for nucleic acids (NA) and protein purification, today announced the launch of 10 new kits for the fast and simple isolation of nucleic acids from blood, plasma and serum, including circulating nucleic acids.

3 Feb 2010

Two young cancer patients receive grants from ProCure Cancer Foundation

Two young cancer patients from Virginia are the first recipients of grants from the ProCure Cancer Foundation, a new charitable organization that is providing financial assistance to families who cannot afford the nonmedical expenses associated with proton therapy.

3 Feb 2010

Canary Foundation researcher awarded $11.5M NIH POCRC SPORE grant for early detection ovarian cancer research

Canary Foundation announces its first researcher, Nicole Urban, Sc.D., and collaborators are awarded 5 years of renewed funding from the National Institutes of Health (NIH) for the Pacific Ovarian Cancer Research Consortium (POCRC) Specialized Programs of Research Excellence (SPORE). The SPORE grant will allow Dr. Urban and fellow researchers to continue work in locating tumor markers and developing blood tests to identify and assess risk and early detection of ovarian cancer. The Listwin Family Foundation and Canary Foundation have been funding Dr. Urban's research since 2002.

3 Feb 2010

GenSpera’s G-115 anti-cancer drug awarded US patent

GenSpera, Inc. announced that its patent application, entitled “Tumor Activated Prodrugs,” has been issued by the United States Patent and Trademark Office (USPTO) as US Patent 7,635,682. The patent covers the composition and potential uses of G-115, GenSpera’s second anti-cancer drug in development.

2 Feb 2010

Spectrum Pharmaceuticals signs co-development and commercialization agreement with TopoTarget A/S

Spectrum Pharmaceuticals, a commercial-stage biotechnology company with a primary focus in oncology, today announced that it has entered into a co-development and commercialization agreement with TopoTarget A/S for Belinostat, a novel histone deacetylase (HDAC) inhibitor.

2 Feb 2010

Gene mutation can trigger preterm births, says study

Mutation of a gene that helps protect the body from genetic instability leads to cellular and molecular changes in the pregnant uterus that trigger premature birth, according to a study appearing online Feb. 1 in the Journal of Clinical Investigation.

2 Feb 2010

Findings could lead to new therapeutic strategies for obesity

Peptides that target blood vessels in fat and cause them to go into programmed cell death (termed apoptosis) could become a model for future weight-loss therapies, say University of Cincinnati (UC) researchers.

2 Feb 2010

Scientists develop potential new treatment against ovarian cancer

Scientists at Georgia Tech and the Ovarian Cancer Institute have further developed a potential new treatment against cancer that uses magnetic nanoparticles to attach to cancer cells, removing them from the body.

2 Feb 2010

IMRT and extensive safety measures can prevent radiation injuries in cancer patients, says oncology expert

Recent media stories have reported isolated cases of cancer patients who were injured by incorrect doses from intensity-modulated radiation therapy (IMRT).

2 Feb 2010

New research shows tumor suppressor p53 prevents cancer progression in cells

Cells missegregate a chromosome approximately once every hundred divisions. But don't be too alarmed: new research in the Journal of Cell Biology shows that the tumor suppressor p53 limits the growth of cells with incorrect numbers of chromosomes and prevents their progression toward cancer.

2 Feb 2010

Tumor News and Research

ASTRO and ACR release practice guidelines for new radiation treatments

BioMarin Pharmaceutical signs stock purchase agreement to acquire LEAD Therapeutics

Study on the role of MCP-1 in obese patients with pancreatic cancer

Researchers uncover new mechanism to protect individuals from serious complications of obesity

Anti-inflammatory plant derivative could play a role in cancer treatment, say MCG researchers

Brentuximab vedotin-chemotherapy combination clinical trial for Hodgkin lymphoma announced

Iodoprovidone exhibits safety and efficiency in management of malignant pleural effusion

TGen, Horizon Discovery partner in development of novel cancer cell-lines

Baker's yeast promising against cancer

News article on the evolving role of hyperthermia in cancer therapy

10 new kits available for fast and simple isolation of nucleic acids from blood, plasma and serum

Two young cancer patients receive grants from ProCure Cancer Foundation

Canary Foundation researcher awarded $11.5M NIH POCRC SPORE grant for early detection ovarian cancer research

GenSpera’s G-115 anti-cancer drug awarded US patent

Spectrum Pharmaceuticals signs co-development and commercialization agreement with TopoTarget A/S

Gene mutation can trigger preterm births, says study

Findings could lead to new therapeutic strategies for obesity

Scientists develop potential new treatment against ovarian cancer

IMRT and extensive safety measures can prevent radiation injuries in cancer patients, says oncology expert

New research shows tumor suppressor p53 prevents cancer progression in cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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