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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New gene therapy vector developed for transferring therapeutic DNA to a cell's nucleus

A research report featured on the cover of the September 2009 print issue of The FASEB Journal describes how Australian scientists developed a new gene therapy vector that uses the same machinery that viruses use to transport their cargo into our cells. As a result of this achievement, therapeutic DNA can be transferred to a cell's nucleus far more efficiently than in the past, raising hopes for more effective treatment of genetic disorders and some types of cancers.

1 Sep 2009

GenoCAD project receives financial support from NSF

The National Science Foundation (NSF) has awarded a three-year $1,421,725 grant to Jean Peccoud, associate professor at the Virginia Bioinformatics Institute at Virginia Tech, to develop GenoCAD - a web-based Computer Assisted Design environment for synthetic biology.

1 Sep 2009

Tel Aviv University researcher devises mathematical formula for protecting the genetic privacy

Last year, after a published paper found serious security holes in the way DNA data is made publicly available, health institutes in the United States and across the world removed all genetic data from public access.

1 Sep 2009

ChromoCure releases development plan for CS300 Chromosomal Scanner

ChromoCure, Inc. (PINKSHEETS: KKUR) released today its development plan for its next generation of chromosomal scanners. The new system has been given the name "CS300" as the next iteration of its current CS200 Chromosomal Scanner design.

1 Sep 2009

Study provides insights into genes that help maintain youthfulness of the skin

In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome."

1 Sep 2009

Natural food compounds may play a vital role in cancer treatment

Research in the Linus Pauling Institute at Oregon State University suggests that some natural food compounds, which previously have been studied for their ability to prevent cancer, may be able to play a more significant role in treating it - working side-by-side with the conventional drugs that are now used in chemotherapy.

1 Sep 2009

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene.

31 Aug 2009

Nuevolution partners with Novartis for drug research

Nuevolution A/S today announced that it has entered into a drug discovery collaboration with Novartis.

31 Aug 2009

New radiotherapy treatment devised for treating women with metastatic ovarian cancer

In the future, women with metastatic ovarian cancer could be treated with a radioactive substance that can seek and destroy tumour cells. An initial study in patients conducted jointly by the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital has found that the treatment has no unwanted side-effects.

31 Aug 2009

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Geneuity Clinical Research Services announces the recent validation and use in clinical trials of two human biomarker assays that play a key role in the early detection of kidney damage.

29 Aug 2009

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

The National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $11.2 million grant to study the impact of damage to DNA on aging and disease. Research funded by this grant, and conducted by a consortium of scientists, could reveal the role of genome maintenance systems in delaying aging and will begin to explore novel interventions to maintain health in old age.

28 Aug 2009

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

Abbott announced today that it has entered into an agreement with Pfizer Inc to develop a molecular diagnostic test intended to screen non-small cell lung cancer (NSCLC) tumors for the presence of gene rearrangements.

28 Aug 2009

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

Cardium Therapeutics today reported that a recent medical journal article highlights the challenges facing healthcare providers with respect to finding optimal treatments for patients with non-healing wounds.

28 Aug 2009

CRi's Oosight imaging system used for developing a gene transfer technique to prevent inherited diseases

U.S. researchers using CRi's Oosight(TM) imaging system have developed a gene transfer technique that has potential to prevent inherited diseases passed on from mothers to their children through mutated DNA in cell mitochondria.

28 Aug 2009

Chk1 and Fbx6 play an important role for the regulation of response to chemotherapy

Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.

28 Aug 2009

HLA-Cw*0602 gene variation detected as a high risk for psoriasis

A specific genetic region that has been increasingly identified as the strongest genetic link to psoriasis has an even more significant role in the chronic skin disease than has been suspected, University of Utah medical researchers show in a new study.

27 Aug 2009

Fluidigm manufactures more than 250 million microscopic NanoFlex valves at its Singapore biochip factory

Fluidigm today announced that its Singapore biochip factory has manufactured and shipped more than 250 million microscopic NanoFlex™ valves. The 250 million valves built into Fluidigm’s integrated fluidic circuits (IFCs) would be equivalent to the number of valves required for all the conventional plumbing – both residential and commercial – in a metropolitan region the size of the San Francisco Bay Area.

27 Aug 2009

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

A novel electronic sensor array for more rapid, accurate and cost-efficient testing of DNA for disease diagnosis and biological research has been developed by scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN).

27 Aug 2009

Nanogap sensor array for ultra-sensitive detection of human DNA

Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. Such tests are done for criminal investigation, disease diagnosis, and other purposes.

27 Aug 2009

Research study reveals that high-fructose corn syrup is used as a sweetener in beverages

Researchers have established the conditions that foster formation of potentially dangerous levels of a toxic substance in the high-fructose corn syrup (HFCS) often fed to honey bees.

27 Aug 2009

DNA News and Research

Further Reading

New gene therapy vector developed for transferring therapeutic DNA to a cell's nucleus

GenoCAD project receives financial support from NSF

Tel Aviv University researcher devises mathematical formula for protecting the genetic privacy

ChromoCure releases development plan for CS300 Chromosomal Scanner

Study provides insights into genes that help maintain youthfulness of the skin

Natural food compounds may play a vital role in cancer treatment

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Nuevolution partners with Novartis for drug research

New radiotherapy treatment devised for treating women with metastatic ovarian cancer

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

CRi's Oosight imaging system used for developing a gene transfer technique to prevent inherited diseases

Chk1 and Fbx6 play an important role for the regulation of response to chemotherapy

HLA-Cw*0602 gene variation detected as a high risk for psoriasis

Fluidigm manufactures more than 250 million microscopic NanoFlex valves at its Singapore biochip factory

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

Nanogap sensor array for ultra-sensitive detection of human DNA

Research study reveals that high-fructose corn syrup is used as a sweetener in beverages

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