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Ethanol treatment may be instrumental in fighting IV-based infections

Inserted through the skin and into a vein, long-term intravascular devices such as IV catheters deliver to patients a range of life-saving medications, nutrition and fluids, among other uses.

11 Aug 2005

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Postmenopausal women who took a bone-building drug for one year followed by a year on a standard drug that fights bone loss experienced greater increases in bone density than has been reported from any other drug regimen, an NIH-sponsored study has found. Bone density is the standard predictor of fracture risk associated with osteoporosis.

11 Aug 2005

FDA approval sought for Pfizer's new cancer drug

Drug company Pfizer has announced it has submitted a New Drug Application (NDA) for its cancer drug Sutent, to the U.S. Food and Drug Administration (FDA).

11 Aug 2005

Majority of Americans believe that vaccines are the best hope for controlling the global AIDS epidemic

But while most of those surveyed felt it personally important to help support HIV vaccine research, a majority expressed reluctance to support a friend or family member's participation in an HIV vaccine clinical trial.

9 Aug 2005

Cognitive therapy can have a preventive effect for depression

Three years ago, Terry Tuton was laid off from his job as project manager at a large technology firm, leaving him limited insurance coverage at a time when he was suffering from overpowering feelings of hopelessness and depression - and not for the first time in his life.

4 Aug 2005

Successful visceral leishmaniasis vaccine trial in dog

Visceral leishmaniasis, which is the most severe form of that group of diseases, affects 500 000 people in the world each year. It is caused by a protozoan, Leishmania infantum, transmitted by sand fly bites.

2 Aug 2005

Living Cell Technologies announces results for treating Huntington's disease

Living Cell Technologies announced pre-clinical results today showing its brain protection product, NeurotrophinCell (NtCell) produces a marked reduction in the size of brain lesions in a Huntington's disease (HD) model.

2 Aug 2005

MediciNova starts phase II clinical trial of MN-166 for multiple sclerosis

MediciNova today announced the enrollment of patients in a Phase II clinical study with MN-166 for the treatment of multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. MN-166 is an orally administered drug with a novel mechanism of action that includes the inhibition of phosphodiesterase IV.

2 Aug 2005

Link between peritoneum closure and fewer adhesions

A controversial surgical procedure that has lost favor among medical professionals may benefit women who have had caesarean sections. So say researchers at the Stanford University School of Medicine, who have found that closing the parietal peritoneum, a multi-layered membrane that lines the abdomino-pelvic walls, substantially decreases the likelihood of scarring that can make future C-sections more difficult.

1 Aug 2005

Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Beta-blockers 'blot out memories' for sufferers with post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) affects around one in three of people caught up in such events, as the London bombings, and memories can be triggered just by a sound or smell.

29 Jul 2005

Breakthrough in stem cells research with pigs - exciting news for heart patients

In exciting news for heart patients, researchers say they have successfully used stem cells to treat heart attack tissue damage in pigs.

27 Jul 2005

Cancer vaccine combined with hormone-deprivation therapy can help patients with recurrence of prostate cancer

A new study finds that a cancer vaccine combined with hormone-deprivation therapy can help patients with recurrence of prostate cancer. The results of this clinical trial, led by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, appear in the August 2005 issue of the Journal of Urology.

26 Jul 2005

Analysis of the Phase I/II clinical trial of HIV drug candidate PA-457

V.I. Technologies (Vitex) and collaborators at the University at Buffalo's School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY, today presented a detailed analysis of the Phase I/II clinical trial of its HIV drug candidate PA-457 at the 3rd International AIDS Society (IAS) Conference on HIV Pathogenesis and Treatment in Rio de Janeiro, Brazil.

26 Jul 2005

Investigational vaccine against Clostridium difficile

Acambis has announced that earlier this month it started a Phase I clinical trial of its investigational vaccine against Clostridium difficile (C. difficile).

26 Jul 2005

Mixture of 8 bacteria (VSL#3) for 6 weeks helps ulcerative colitis

A mixture of bacteria developed in part by University of Alberta researchers has been proven highly effective in treating people suffering from ulcerative colitis.

25 Jul 2005

Testosterone patch may produce modest increases in sexual desire

A testosterone patch may produce modest increases in sexual desire and frequency of satisfying sexual experiences in women who develop distressful, low sexual desire following hysterectomy and removal of the fallopian tubes and ovaries, according to a study in the July 25 issue of Archives of Internal Medicine.

25 Jul 2005