Clinical Trial News and Research

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Evaluating how hospitals deliver medical care standardizes practices and improves care

In recent years, American hospitals have made significant improvements on standardized, evidence-based measures of clinical performance for several medical conditions, including heart attacks, heart failure, and pneumonia.

20 Jul 2005

Spontaneous contractions suppressed in late-term rat pregnancy

A long-time aim of obstetrical research has been to find agents that could delay or diminish pre-term labor because even today pre-term birth is a leading cause of infant mortality and morbidity.

19 Jul 2005

Results demonstrate the safety and tolerability of ABthrax treatment for Anthrax infection

Human Genome Sciences has announced that results published in the current issue of Clinical Infectious Diseases demonstrate that the first investigational agent against anthrax infection to be evaluated in a clinical study since the 2001 anthrax attacks in the United States, is safe, well tolerated and achieves the blood levels predicted by relevant animal models as necessary to afford significant protection from the lethal effects of the anthrax toxin

19 Jul 2005

Vagal nerve stimulation, an innovative therapy for depression

The Saint Louis University Health Sciences Center medical team involved in the research and development of an innovative therapy for depression - vagal nerve stimulation (VNS) - is starting a new clinic for patients who have treatment-resistant depression.

19 Jul 2005

Regular yoga practice may help prevent middle-age spread

A new study led by researchers at Fred Hutchinson Cancer Research Center has found that regular yoga practice may help prevent middle-age spread in normal-weight people and may promote weight loss in those who are overweight.

19 Jul 2005

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

The findings, which appear in the July issue of the journal Molecular Cancer Therapeutics, could lead to a treatment that provides an effective option to surgically removing the cancer, helping patients preserve vital organs involved in speech and swallowing.

18 Jul 2005

Nebivolol may help control high blood pressure

According to research presented at ISHIB2005, nebivolol was shown to be statistically significantly better than placebo in reducing systolic and diastolic blood pressure among African-American hypertensive patients in a multicenter, randomized, double-blind, placebo-controlled study.

18 Jul 2005

Chemical sealant - poloxamer 188 can repair damage to cardiac muscle cell membrane

A common chemical used in the manufacturing and pharmaceutical industries can repair damage to cardiac muscle cell membranes and prevent heart failure in mice with the genetic mutation that causes Duchenne muscular dystrophy, according to scientists at the University of Michigan Medical School.

18 Jul 2005

Scientists have begun to clarify how one of the body's molecules controls the trafficking of T cells through the blood

...lymph nodes and on to tissues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own tissues and causing autoimmune diseases.

17 Jul 2005

New compound ruboxistaurin may decrease vision loss in diabete

A multicenter international study chaired by a Joslin Diabetes Center investigator and reported in the July issue of the American Diabetes Association's journal Diabetes brings hopeful news to the 18 million people in the United States -- and millions more worldwide -- with type 1 or type 2 diabetes.

15 Jul 2005

Desire more important than therapy for quitting alcohol

The positive outcomes of therapy for alcoholism may have less to do with the therapy itself and more to do with participants' determination to quit.

13 Jul 2005

Australian product promotes healing in venous stasis ulcers

Novogen has announced the results of a Phase II clinical trial of its investigational wound healing compound, Glucoprime, in venous stasis ulcers.

13 Jul 2005

Acupuncture no help for fibromyalgia sufferers

Fibromyalgia is a condition that causes pain and tenderness in the head, shoulders, upper back, thighs, and abdomen and sufferers also often have headaches, fatigue, anxiety, depression, and sleep problems.

7 Jul 2005

Neurological complication may result from rapid withdrawal from pregabalin

A report in the July Annals of Neurology describes a serious adverse event experienced by a participant in a clinical trial that may raise a new caution about the use of antiepileptic drugs for conditions other than epilepsy.

6 Jul 2005

Vitamin E supplements do not protect healthy women against heart attacks and stroke

Vitamin E supplements do not protect healthy women against heart attacks and stroke, according to new results from the Women's Health Study, a long-term clinical trial of the effect of vitamin E and aspirin on both the prevention of cardiovascular disease and of cancer.

5 Jul 2005

New drug candidate against HIV-infection

As a part of a research collaboration, scientists at the Sahlgrenska Academy at Gotenborg University, Sweden, have developed a new drug candidate against HIV-infection. The new substance, named alphaHGA, will be tested on patients this year.

30 Jun 2005

Myriad Genetics issued new patent under license

Myriad Genetics has announced the issuance of Patent No. 6,911,466 entitled, "AB42 Lowering Agents". Myriad holds exclusive rights to the patent under a licensing agreement with Mayo Clinic. The patent covers methods of using a broad class of compounds known as selective amyloid beta 42 lowering agents (SALAs) to lower levels of the toxic peptide.

29 Jun 2005

Major study says for diabetics with high blood pressure diuretics are the best option

A major new study has found that for people with type 2 diabetes and high blood pressure, cheaper diuretic medications may be the most cost-effective option in reducing hypertension.

29 Jun 2005

Tetracycline antibiotic shows promise for treating osteoarthritis

A tetracycline antibiotic, doxycycline, has been successfully used to treat a wide-range of bacterial infections. In addition to its effects as an antibiotic, doxycycline has other actions as a drug and, in laboratory studies with animals and with human tissue, can inhibit the degradation of cartilage in a way that could be useful for the treatment of osteoarthritis (OA).

28 Jun 2005

Diuretics work better than newer and more costly medicines for diabetics with high blood pressure

Diuretics (water pills) work better than newer and more costly medicines in the treatment of high blood pressure and prevention of some forms of heart disease in people with type 2 diabetes, according to results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

28 Jun 2005

Clinical Trial News and Research

Evaluating how hospitals deliver medical care standardizes practices and improves care

Spontaneous contractions suppressed in late-term rat pregnancy

Results demonstrate the safety and tolerability of ABthrax treatment for Anthrax infection

Vagal nerve stimulation, an innovative therapy for depression

Regular yoga practice may help prevent middle-age spread

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

Nebivolol may help control high blood pressure

Chemical sealant - poloxamer 188 can repair damage to cardiac muscle cell membrane

Scientists have begun to clarify how one of the body's molecules controls the trafficking of T cells through the blood

New compound ruboxistaurin may decrease vision loss in diabete

Desire more important than therapy for quitting alcohol

Australian product promotes healing in venous stasis ulcers

Acupuncture no help for fibromyalgia sufferers

Neurological complication may result from rapid withdrawal from pregabalin

Vitamin E supplements do not protect healthy women against heart attacks and stroke

New drug candidate against HIV-infection

Myriad Genetics issued new patent under license

Major study says for diabetics with high blood pressure diuretics are the best option

Tetracycline antibiotic shows promise for treating osteoarthritis

Diuretics work better than newer and more costly medicines for diabetics with high blood pressure

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