Clinical Trial News and Research

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Brief course of chemotherapy after surgery should be the new standard of care around the world

A Canadian national clinical trial has found that chemotherapy following surgery for early-stage non-small cell lung cancer significantly improves survival for the disease over just surgery alone.

27 Jun 2005

Tricirbine may help fight cancers

H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate.

27 Jun 2005

Wearing a continuous positive airway pressure device helps heart failure patients with obstructive sleep apnea get a good night's rest

Wearing a continuous positive airway pressure (CPAP) device not only helps heart failure patients with obstructive sleep apnea get a good night's rest, it lowers blood pressure and heart rate well into the morning, apparently, by reducing sympathetic nervous system activity, according to a new study (PDF) in the June 21, 2005, issue of the Journal of the American College of Cardiology.

21 Jun 2005

Bipolar disorder more prevalent and costly than believed

The incidence of bipolar disorder in the general population is considerably higher than earlier studies have indicated, resulting in significantly less productivity and more days lost from work compared to the better known major depressive disorder, according to preliminary findings from a national survey presented today at the Sixth International Conference on Bipolar Disorder.

19 Jun 2005

Neurocrine Biosciences issued new U.S. patent

Neurocrine Biosciences announced today the issuance of U.S. Patent No. 6,903,106 covering a novel polymorphic form (different crystal structure) of its proprietary compound indiplon for the treatment of insomnia.

16 Jun 2005

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Treating babies who have sickle cell disease (SCD) with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude Children's Research Hospital.

16 Jun 2005

Antifungal drug could improve lives of thousands of asthmatics

Researchers in the UK say that antifungal drugs could be the key to improving the lives of thousands of asthmatics.

From The University of Manchester 16 Jun 2005

Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

15 Jun 2005

Promising new tuberculosis drug enters clinical trial

A promising new drug candidate that may be effective against both actively dividing and slow-growing Mycobacterium tuberculosis (M. tb) has begun testing in humans, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced this week.

15 Jun 2005

Report on Hispanics and genes, culture, and medicines highlights the rise of individualized medicine

"The FDA's review today of BiDil could make it the first drug approved specifically for African Americans and marks the end of 'one-size-fits-all' medicine," said Dr. Jane L. Delgado, President and CEO of the National Alliance for Hispanic Health (the Alliance), the nation's leading Hispanic health advocacy group.

15 Jun 2005

Abstinence education programs increased youth's support for abstinence

The initial findings from a one-year followup of 2,310 students participating in an evaluation of four abstinence-only education programs show that the programs increased support for abstinence.

15 Jun 2005

Panel advise limited use of heart drug Natrecor

An independent panel of experts say heart-failure drug Natrecor should be restricted and only used with acutely ill hospitalized patients.

15 Jun 2005

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.

15 Jun 2005

Chase those monthly blues away with a diet rich in calcium and vitamin D

U.S. researchers say that a diet rich in calcium and vitamin D might very well help banish pre-menstrual syndrome (PMS).

14 Jun 2005

Chemokine Therapeutics granted new U.S patent

Chemokine Therapeutics has announced that it has been granted U.S. Patent No. 6,875,738 relating to the use of its anti-cancer compound, CTCE-9908, in the treatment of cancer and inhibition of angiogenesis. CTCE-9908 is designed to block CXCR4, a receptor found on the surface of cancer cells.

14 Jun 2005

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Eli Lilly and Company today announced encouraging results from a one-year pilot study examining the effect of ruboxistaurin mesylate in persons with type 2 diabetes and kidney disease (also known as "diabetic nephropathy").

12 Jun 2005

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Diabetic retinopathy has been found in nearly 8 percent of pre-diabetic participants in the Diabetes Prevention Program (DPP), according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Schering-Plough announced today that the European Commission has granted approval of Temodal (temozolomide) Capsules for first-line use for the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), the most common and aggressive form of primary brain cancer.

10 Jun 2005

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Digital mammography provides no clear-cut improvements over traditional film X-rays in the ability to detect cases of breast cancer, says a new technology assessment report. The technology does, however, offer other benefits, including slightly lower radiation doses for patients, that may prompt its increasing use despite its much higher costs.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Clinical Trial News and Research

Brief course of chemotherapy after surgery should be the new standard of care around the world

Tricirbine may help fight cancers

Wearing a continuous positive airway pressure device helps heart failure patients with obstructive sleep apnea get a good night's rest

Bipolar disorder more prevalent and costly than believed

Neurocrine Biosciences issued new U.S. patent

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Antifungal drug could improve lives of thousands of asthmatics

Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

Promising new tuberculosis drug enters clinical trial

Report on Hispanics and genes, culture, and medicines highlights the rise of individualized medicine

Abstinence education programs increased youth's support for abstinence

Panel advise limited use of heart drug Natrecor

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

Chase those monthly blues away with a diet rich in calcium and vitamin D

Chemokine Therapeutics granted new U.S patent

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

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