Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

16 Aug 2022

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases.

12 Aug 2022

Specific factors may affect physical and mental quality of life among people with multiple sclerosis

Quality of life is a measure of a person's level of comfort, health and happiness. For people with multiple sclerosis (MS), a new study has found there are specific factors that may affect a person's physical and mental quality of life.

10 Aug 2022

Leisure activities may help lower the risk of dementia

Leisure activities, such as reading a book, doing yoga and spending time with family and friends, may help lower the risk of dementia, according to a new meta-analysis published in the August 10, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

10 Aug 2022

Abnormal size or functioning in the heart's left atrium may increase dementia risk

Structural or functional abnormalities within the heart's left atrium, with or without symptoms, may increase a person's risk of developing dementia later in life by 35%, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Aug 2022

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Research led by Drs. Yuhai Zhao and Walter J Lukiw at the LSU Health New Orleans Neuroscience Center and the Departments of Cell Biology and Anatomy, Neurology and Ophthalmology, reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer's disease (AD).

9 Aug 2022

UNH researchers receive $2.8 million NIH grant to develop and test social assistive robots

Researchers at the University of New Hampshire will receive a five-year grant totaling $2.8 million from the National Institutes of Health (NIH) to develop and test social assistive robots to aid in the care of individuals with Alzheimer's disease and related dementia in the comfort of their own homes.

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

How do female sex hormones affect sleep, and memory?

Scientists describe the relationship between biological sex, memory, sleep, and hormones in relation to the risk of Alzheimer's disease and related dimentias.

7 Aug 2022

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (Aβ), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease Aβ plaque burden in AD patients, its effect on cognitive improvement is still controversial.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

Common viruses may play a role in some cases of Alzheimer's disease

Researchers from Oxford's Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer's disease (AD).

3 Aug 2022

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

3 Aug 2022

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

In a new study, researchers assessed the genetic variation among targets of Alzheimer's disease risk and anti-diabetic drugs.

3 Aug 2022

Novel age predictor helps investigate heterogeneity in brain aging

A new research paper was published in Aging (abbreviated as "Aging (Albany NY)" by Medline/PubMed and as "Aging-US" by Web of Science) on the cover of Volume 14, Issue 14, entitled, "Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease."

3 Aug 2022

Alzheimer's Disease News and Research

Further Reading

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Specific factors may affect physical and mental quality of life among people with multiple sclerosis

Leisure activities may help lower the risk of dementia

Abnormal size or functioning in the heart's left atrium may increase dementia risk

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

UNH researchers receive $2.8 million NIH grant to develop and test social assistive robots

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Researchers unravel a novel molecular target of eicosapentaenoic acid

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

How do female sex hormones affect sleep, and memory?

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

Common viruses may play a role in some cases of Alzheimer's disease

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Novel age predictor helps investigate heterogeneity in brain aging

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