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CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016

Advances in the field of MPI: an interview with Professor Kannan Krishnan

In around 2004, there was a Phillips paper that discussed a new imaging technique called MPI. At that time, I had an eager, promising graduate student named Matt Ferguson who wanted a project, so I asked him to take a look.

From Bruker BioSpin Group 1 Mar 2016

Cryo-electron microscopy helps analyze infection mechanisms of coronaviruses in detail

High-resolution cryo-electron microscopy and supercomputing have now made it possible to analyze in detail the infection mechanisms of coronaviruses. These viruses are notorious for attacking the respiratory tract of humans and animals.

27 Feb 2016

Rockefeller research reveals vital new component of system responsible for regulating food intake

The molecular intricacies of hunger and satiety, pivotal for understanding metabolic disorders and the problem of obesity, are not yet fully understood by scientists. However, new research from The Rockefeller University reveals an important new component of the system responsible for regulating food intake: a hormone called amylin, which acts in the brain to help control consumption.

27 Feb 2016

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer's patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.

27 Feb 2016

Ground-breaking discovery could lead to new treatments for diabetes

Why would a bacteria-killing protein be present in an area of the body that is not normally exposed to bacteria, like the pancreas? Researchers at The Ottawa Hospital and the University of Ottawa puzzled over this question for some time, until they eventually discovered that the protein in question was doing something entirely unexpected - it was actually helping the pancreas regenerate and produce insulin.

25 Feb 2016

Unique cardiovascular disease risk calculator for black adults may not be necessary: Study

Although cardiovascular disease risk prediction models are developed with predominantly white populations, application of models to a large black population finds that they work well in black individuals and are not easily improved on, suggesting that a unique risk calculator for black adults may not be necessary, according to a study published online by JAMA Cardiology.

25 Feb 2016

Parvus' novel therapeutic approach employing nanomedicines published in Nature

Parvus Therapeutics today announced the publication in Nature of a seminal paper describing the discovery and applications of a novel therapeutic approach employing nanomedicines, referred to as "Navacims"TM, to reprogram white blood cells to become regulatory cells capable of blunting autoimmune responses and restoring the equilibrium of the immune system.

19 Feb 2016

Findings offer new approach to treating metabolic disorders

A new research study has revealed an important relationship between proteins secreted by the heart and obesity, glucose intolerance, and insulin resistance. The findings, published today in Obesity, offer a new approach to treating metabolic disorders, including type 2 diabetes, by targeting the pathway that controls the proteins' concentration in the blood.

18 Feb 2016

More phase II success for CGRP migraine prevention strategy

Another antibody targeting the calcitonin gene-related peptide pathway has proved successful against episodic migraine in a phase II trial.

18 Feb 2016

Study provides new paradigm for understanding role of immune system in type 1 diabetes

Researchers from The University of Colorado, in collaboration with St Vincent’s Institute of Medical Research in Melbourne, have identified what may be the initial target of the immune response that causes type 1 diabetes.

18 Feb 2016

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

A small peptide dubbed TAxI is living up to its name. Recent studies show it to be an effective vehicle for shuttling functional proteins, such as active enzymes, into the spinal cord after a muscle injection.

17 Feb 2016

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is frequently mutated in children on the autism spectrum. In older men and women, ADNP expression in the blood is correlated with cognition and further altered in Alzheimer's disease.

11 Feb 2016

Penn investigators explore new treatment option for cocaine dependence

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence.

11 Feb 2016

Older people could be at greater risk for negative consequences of consuming high-salt diet

Aging is associated with a number of changes that cause the body to function less efficiently, including the way the body controls water and sodium levels. Research has shown that as humans and animals age, they are less able to regulate sodium and water retention, urine concentration and thirst compared to their younger counterparts.

9 Feb 2016

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

"You must remember this: a kiss is just a kiss, a sigh is just a sigh." Contrary to the words immortalized by the piano singer in "Casablanca," a sigh is far more than a sigh. Heaving an unconscious sigh is a life-sustaining reflex that helps preserve lung function.

9 Feb 2016

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels.

8 Feb 2016

Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Cerapedics, a privately-held orthobiologics company, announced today results from a pivotal FDA Investigational Device Exemption (IDE) clinical trial for i-FACTOR Peptide Enhanced Bone Graft in anterior cervical discectomy and fusion (ACDF) procedures have been electronically published in the peer-reviewed journal Spine.

8 Feb 2016

Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Björn Wängler

Interview conducted with Professor Björn Wängler, Professor for Molecular Imaging and Radiochemistry from Heidelberg University.

From Bruker BioSpin Group 4 Feb 2016

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.

29 Jan 2016

Peptides News and Research

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

Advances in the field of MPI: an interview with Professor Kannan Krishnan

Cryo-electron microscopy helps analyze infection mechanisms of coronaviruses in detail

Rockefeller research reveals vital new component of system responsible for regulating food intake

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

Ground-breaking discovery could lead to new treatments for diabetes

Unique cardiovascular disease risk calculator for black adults may not be necessary: Study

Parvus' novel therapeutic approach employing nanomedicines published in Nature

Findings offer new approach to treating metabolic disorders

More phase II success for CGRP migraine prevention strategy

Study provides new paradigm for understanding role of immune system in type 1 diabetes

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Penn investigators explore new treatment option for cocaine dependence

Older people could be at greater risk for negative consequences of consuming high-salt diet

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Björn Wängler

Researchers develop new painkiller as strong as morphine but not addictive

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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