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A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

In a literature review article published in the Journal of Community Hospital Internal Medicine Perspectives, authors from the US performed a thorough investigation of previous studies and case reports of SARS-CoV-2 reinfection. This review discusses the role of natural immunity, vaccines, and SARS-CoV-2 variants in reinfection.

25 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

Using metal nanoparticles to fight SARS-CoV-2

A recent review article looks at the potential of nanotechnology in fighting severe acute respiratory syndrome 2 (SARS-CoV-2), with several possibilities of strategies in therapeutics, vaccines, and prevention.

25 Nov 2021

Study demonstrates effectiveness of two doses of BBV152 vaccine against COVID-19

In a study published in The Lancet Infectious Diseases, researchers investigated the effectiveness of the BBV152 vaccine among employees of the All India Institute of Medical Sciences.

25 Nov 2021

Breakthrough infections from SARS-CoV-2 Delta variant among vaccinated healthcare workers

A new study published on the medRxiv* preprint server employed in-silico techniques, combining genomic and epidemiological data, to determine possible Delta-variant transmission events between vaccinated healthcare workers (HCWs) in Indian hospitals.

25 Nov 2021

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

In this perspective, a new study published on the medRxiv* preprint server analyzed the clinical efficacy of two serum antigen tests to identify SARS CoV-2 infection and evaluate the kinetics of serum nucleocapsid (N) antigen in severe and non-severe patients for disease severity prediction.

24 Nov 2021

Can dexamethasone reduce prolonged COVID-19 symptoms?

A new study assesses hospitalized patients after recovering from COVID-19 by comparing the individuals before and after being treated with dexamethasone.

24 Nov 2021

Healthcare workers at increased SARS-CoV-2 infection risk during second wave

A new study evaluates the SARS-CoV-2 infection rates among healthcare workers during the second wave of the COVID-19 pandemic.

24 Nov 2021

Markers of SARS-CoV-2 shedding in vaccinated and unvaccinated individuals

The study uses serial mid-turbinate nasal specimens collected from a subset of incarcerated persons infected during this outbreak.

24 Nov 2021

Limited immune responses three months after Pfizer-BioNTech vaccination among elderly

In this study, published on the medRxiv* preprint server, the humoral response to SARS-CoV-2 was assessed before and after three months of administration of the BNT162b2 mRNA COVID-19 vaccination (Pfizer-BioNTech). In addition, elders' humoral responses were compared to those of a younger group, and a functional neutralization experiment against the Wuhan-Hu-1 (WH1) virus and the Delta variant was carried out.

23 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

An increase in the half-life of remdesivir for COVID-19 treatment

In this study, researchers analyzed several drug candidates to investigate their efficacy against a broad spectrum of coronaviruses in cell culture studies.

23 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

Success of covid antiviral pills hinges on access to speedy and accurate tests

Within a few weeks, perhaps before many Americans finish decorating for the holidays, the U.S. could have access to a new antiviral pill from Merck expected to alter the deadly trajectory of the covid-19 pandemic — with a second option from Pfizer to follow shortly after.

22 Nov 2021