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Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Scientists develop an improved biosensor with Cas12a-based CRISPR on-site rapid detection system and discuss its ability to detect SARS-CoV-2 VOCs.

7 Dec 2021

SARS-CoV-2 re-infection from new variant after natural infection

Researchers survey incidences of SARS-CoV-2 infection in both care home staff and residents early in the pandemic.

7 Dec 2021

Method for inactivation and direct RT-qPCR of SARS-CoV-2

Researchers from the University of Edinburgh have been exploring ways to optimize this process further, allowing RT-qPCR to work more efficiently by eliminating one of the key steps.

7 Dec 2021

Study suggests algal polysaccharide may be a promising anti-COVID-19 candidate

Researchers from the Rensselaer Polytechnic Institute have been investigating the potential of rhamnan sulfate as an antiviral agent.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

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5 Dec 2021

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

In this paper, a group of researchers from Harvard Medical School, McGill University, and Tianjin University describes an on-chip diagnostic technology for the direct detection of SARS-CoV-2 N protein in nasal samples that combines the advantages of hydrodynamic microfluidic filtration and sandwich immunoassay.

5 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

SARS-CoV-2 causes the pandemic coronavirus disease COVID-19, that is more harmful for elderly people, who show more severe symptoms and are at higher risk of hospitalization and death.

3 Dec 2021

New bioinformatics method for viral sgRNA analysis

A recent study discusses a bioinformatics method to help identify and explore sgRNAs uncovered in next-generation sequencing data.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

A recent study describes the association between time elapsed since the second dose of the Pfizer-BioNTech BNT162b2 vaccine and risk of COVID-19.

1 Dec 2021

SARS-CoV-2 transmission across age groups makes age-based interventions ineffective

Researchers review critically evaluated the transmission dynamics of SARS-CoV-2 across various ages in metropolitan France.

1 Dec 2021

Deactivating the cancer-causing protein by cutting off other proteins that activate it

In a line of dominos, if you take out a single piece, the last one will never fall. Similarly, a lot of pieces have to line up and be pushed at the same time in a cell to result in cancer.

1 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

New research examined SARS-CoV-2 transcripts in order to understand how it expresses its gene products in the infected host.

1 Dec 2021

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Natural infection with COVID-19 offered protection from reinfection when the gamma and delta variants predominated, according to a new University of Michigan study that also provides levels of antibodies needed to protect against reinfections.

30 Nov 2021

Scientists identify a new therapeutic target for HIV

Scientists in Montreal and London have identified the key role played by transcription factorRORC2 in HIV infection: the molecule attaches itself to parts of the virus's genome yet doesn't prevent it from replicating.

30 Nov 2021

Study shows that nucleic acid amplification tests more accurate in detecting SARS-CoV-2 than rapid antigen

Researchers use reference preparations from pooled swab samples to compare the analytical sensitivity of different SARS-CoV-2 assays

30 Nov 2021

Transcription News and Research

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

SARS-CoV-2 re-infection from new variant after natural infection

Method for inactivation and direct RT-qPCR of SARS-CoV-2

Study suggests algal polysaccharide may be a promising anti-COVID-19 candidate

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

New bioinformatics method for viral sgRNA analysis

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

SARS-CoV-2 transmission across age groups makes age-based interventions ineffective

Deactivating the cancer-causing protein by cutting off other proteins that activate it

Role of interferon type I-driven responses associated with disease control in COVID-19

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Scientists identify a new therapeutic target for HIV

Study shows that nucleic acid amplification tests more accurate in detecting SARS-CoV-2 than rapid antigen

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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