Clinical Trial News and Research

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New Symbicort single inhaler asthma treatment gives much better asthma control

A new asthma treatment regimen promises to deliver a great improvement in key measures of asthma control and should simplify the management of the disease compared with other treatments.

23 May 2005

International Committee of Medical Journal Editors updates requirements for clinical trials registry

The International Committee of Medical Journal Editors (ICMJE) today issued a follow-up joint editorial regarding its goal to foster a comprehensive, publicly available database of clinical trials. The joint editorial by 11 ICMJE member journals is published online simultaneously today and is posted on the JAMA website. It will also appear in print in the June 15 issue of JAMA.

23 May 2005

Risks outweigh benefits of shark cartilage as anti-cancer treatment

As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance.

23 May 2005

Australian-New Zealand hormone therapy trial good news for prostate cancer patients

Results of a major trial of hormone therapy on men with locally advanced prostate cancer announced today were a significant development and would be welcomed by patients and oncologists world-wide, according to The Cancer Council Australia.

23 May 2005

New product for advanced treatment of chronic wounds

Insense Ltd, a UK biotechnology company, announced successful clinical trial results for "Oxyzyme", a new product for advanced treatment of chronic wounds.

23 May 2005

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

Researchers said that developing brain stimulation techniques such as transcranial magnetic stimulation (TMS), vagal nerve stimulation and deep brain stimulation are emerging as significant treatment options for the millions of patients "poorly served" by existing therapies.

23 May 2005

Study finds benefits, less organ rejection using immunosuppressive combination for heart transplants

A new study led by researchers at the UCLA Heart Transplant Program showed that one particular combination using tacrolimus (TAC or PrografÒ also known as FK506) had significant anti-rejection benefits for heart transplant patients over other combinations.

22 May 2005

Proof that chiropractic treatment helps migraine sufferers

Seventy-two per cent of migraine sufferers in a clinical trial experienced either 'substantial' or 'noticeable' improvement after a period of chiropractic treatment, defying historical skepticism of chiropractics by some medical practitioners.

22 May 2005

Exercise programme is as beneficial as spinal surgery in treating lower back pain

The largest ever clinical trial of surgery versus exercise treatments for chronic low back pain has found that patients may obtain as much benefit from an intense physical exercise programme as from spinal surgery.

22 May 2005

Novel way of administering an anti-cancer drug to bone-marrow transplant patients using continuous infusion

The new method achieves more predictable, stable drug levels in patients than the current method and could eventually allow doctors to more accurately adjust doses to accommodate individual differences in metabolism, thus increasing treatment effectiveness while avoiding side effects, said University of North Carolina at Chapel Hill researchers.

20 May 2005

New kidney test better elder mortality predictor

A study at the San Francisco VA Medical Center (SFVAMC) has found that a test of kidney function that measures blood levels of cystatin C -- a protein produced by most cells in the body -- is a far more accurate predictor of mortality risk in elderly people than the current standard kidney function test, which measures levels of the protein creatinine.

20 May 2005

New study questions benefits of aspirin for the over 70s

The benefits of giving low dose aspirin to healthy people from the age of 70 to prevent heart disease are offset by increased cases of serious bleeding, argue researchers in a study published online by the BMJ this week.

19 May 2005

Australia to establish a national clinical trials register

For the first time, medical researchers, doctors and the general public will have information about clinical trials happening across the country in all areas of health, with the announcement of a national on-line register of all types of clinical trials.

18 May 2005

Advanced breast cancer drug appears effective on multiple targets

An experimental breast cancer drug that simultaneously attacks five tumor targets has halted progression of the disease in a clinical trial for patients with advanced disease.

18 May 2005

Breast cancer chemotherapy regimen associated with life-threatening complications

The chemotherapy regimen of doxorubicin plus docetaxel, used to treat breast cancer in a clinical trial, was associated with an increased risk of serious complications, resulting in the premature termination of the trial, according to a study in the May 18 issue of JAMA.

17 May 2005

Jefferson researcher’s results show promise for metastatic eye melanoma

But now, by simultaneously revving up the immune system and choking off the tumor’s oxygen supply, oncologists at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia may have found a better way to battle this deadly cancer.

17 May 2005

Rifaximin is effective in preventing attacks of diarrhea

An antibiotic can be safely used to prevent attacks of diarrhea that plague millions of globe-trotting vacationers and business travelers, a Houston research team reports this week in the Annals of Internal Medicine.

17 May 2005

Vitamin D, taxotere combination promising for advanced prostate cancer

Results of a new study strongly suggest that DN-101, a new high-dose calcitriol pill designed specifically as a cancer therapy, given in combination with docetaxel (Taxotere) extends the lives of men with advanced prostate cancer.

17 May 2005

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Antibody combined with cancer drug shows promise against breast tumors

An antibody that targets the blood vessels nourishing tumors significantly reduced breast cancer formation and growth in mice when combined with a current cancer drug, according to researchers at UT Southwestern Medical Center.

16 May 2005

Clinical Trial News and Research

New Symbicort single inhaler asthma treatment gives much better asthma control

International Committee of Medical Journal Editors updates requirements for clinical trials registry

Risks outweigh benefits of shark cartilage as anti-cancer treatment

Australian-New Zealand hormone therapy trial good news for prostate cancer patients

New product for advanced treatment of chronic wounds

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

Study finds benefits, less organ rejection using immunosuppressive combination for heart transplants

Proof that chiropractic treatment helps migraine sufferers

Exercise programme is as beneficial as spinal surgery in treating lower back pain

Novel way of administering an anti-cancer drug to bone-marrow transplant patients using continuous infusion

New kidney test better elder mortality predictor

New study questions benefits of aspirin for the over 70s

Australia to establish a national clinical trials register

Advanced breast cancer drug appears effective on multiple targets

Breast cancer chemotherapy regimen associated with life-threatening complications

Jefferson researcher’s results show promise for metastatic eye melanoma

Rifaximin is effective in preventing attacks of diarrhea

Vitamin D, taxotere combination promising for advanced prostate cancer

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Antibody combined with cancer drug shows promise against breast tumors

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