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Tuberculosis fourfold the risk for Celiac sufferers

Swedish researchers are suggesting that people with celiac disease, also known as gluten intolerance, have an increased risk of developing tuberculosis (TB).

17 Oct 2006

Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

Researchers identify cell line that is resistant to retroviruses

Researchers at the University of Minnesota have identified a protein that enables viruses such as HIV to infect cells and spread through the body.

17 Oct 2006

Vaccine that protects mice against 1918 influenza virus developed

Federal scientists have developed a vaccine that protects mice against the killer 1918 influenza virus. They also have created a technique for identifying antibodies that neutralize this virus, a tool that could help contain future pandemic flu strains.

17 Oct 2006

Topical treatment for psoriasis, eliminates need for injections

Apollo Life Sciences, a Sydney-based biotechnology company, has announced that its topical psoriasis treatment has outperformed current market-leading drugs in preclinical studies.

17 Oct 2006

New test on hair can reveal eating disorders

All too often women with eating disorders cannot recognise they have a problem, or go to great lengths to disguise the problem from others.

17 Oct 2006

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.

16 Oct 2006

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

Efforts to treat cancer using genes and other oligonucleotides, such as short interfering RNA (siRNA), that turn off the biochemical processes that trigger malignancies have been hindered by difficulties in delivering nucleic acids to tumors.

16 Oct 2006

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

The interactions between proteins and nucleic acids play a critical role in some of life’s most crucial biochemical processes, including gene expression and protein production, and some promising anticancer agents exert their effects by interfering with these interactions.

16 Oct 2006

Lab-on-a-chip technology for determination of protein isoform profiles

A new microfluidics device that uses immobilized antibodies and carbon nanostrings as detection agents can identify slight variations in protein composition, known as protein isoforms, that could indicate the presence of cancer.

16 Oct 2006

Lower PSA in obese men could be a warning

Researchers in the U.S. say that obese men have lower levels of a protein used to screen for prostate cancer risk, and doctors should take weight into account when determining a man's risk.

10 Oct 2006

Photochemistry creates drug-trapping nanoparticles

Many of the most potent anticancer agents are poorly soluble in water, presenting a challenge for medicinal chemists who must develop methods of delivering these drugs in the watery environment of the human body.

9 Oct 2006

New York Times examines efforts to obtain FDA approval for Abraxane to treat earlier-stage cancer

The New York Times has examined efforts by the pharmaceutical company Abraxis BioScience to obtain FDA approval for its late-stage breast cancer drug Abraxane as a treatment for earlier-stage breast cancer.

5 Oct 2006

Built-in blocker - drug and antidote in the same molecule

In cases of serious side effects or overdoses of medications, it can be vital to have a fast-acting antidote on hand.

2 Oct 2006

Simultaneous synthesis and screening in a microfluidics device

In the quest for new methods to synthesize large numbers of drug leads, medicinal chemists are increasingly turning to microfluidics as a means of performing dozens of chemical reactions using minute quantities of chemical reagents.

From Siemens Healthineers 2 Oct 2006

Temperature-sensitive nanoparticle boosts drug antitumor activity

Using temperature-sensitive, lipid- and polymer-based nanoparticles with a polymer coating, researchers in Korea have created an anticancer drug delivery vehicle that may provide a significant boost to the therapeutic efficacy of anticancer agents, particularly when used in conjunction with hyperthermia.

2 Oct 2006

Smart nanoscale bioreactors for drug delivery

In a powerful demonstration of how to build a multifunctional, smart nanoscale drug delivery system, researchers at the University of Basel have created a drug-loaded nanocontainer that targets specific cells and releases its payload when receiving a specific physiological signal.

2 Oct 2006