Cell Death News and Research

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Simple protocol rescues stressed liver cells

Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte quality and enables cells from a wider quality spectrum to be used in standard and advanced cell culture. The findings are published in Archives of Toxicology.

21 Dec 2018

Study reveals how Parkinson's disease protein 'buys time' for cell repair

Australian researchers have discovered how a protein linked to Parkinson's disease may protect cells such as neurons in the brain.

20 Dec 2018

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

The importance of research into the role of the immune system in the development and therapy of oncological diseases was emphasized by the Royal Swedish Academy, which recently named James Allison and Tasuku Honjo recipients of the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor.

20 Dec 2018

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even against dividing healthy cells.

18 Dec 2018

Immune cells explode themselves to inform about the danger of invading bacteria

Our immune systems are working overtime this time of year. Knowing that a bunch of dedicated immune cells are willing to explode themselves to inform other cells about the danger may offer a bit of consolation.

17 Dec 2018

Weakened metabolism of immune T cells may account for serious complications in elderly

The elderly suffer more serious complications from infections and benefit less from vaccination than the general population.

14 Dec 2018

New substance could improve efficacy of established breast cancer treatments

Physicians from Karl Landsteiner University of Health Sciences in Krems (Austria) demonstrate potential for clinical application, collaborating with research groups from Germany, the USA, and China.

13 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

Sacrificial immune cells alert body to infection

Scientists have discovered a new mechanism by which immune cells burst to alert the body to infection with Yersinia pestis.

11 Dec 2018

Researchers gain new insights into pediatric tumors

Peripheral nervous system tumors are one of the most common types of childhood tumors. While some of these tumors, known as neuroblastoma, disappear on their own without treatment, others will continue to grow even despite intensive treatment.

10 Dec 2018

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

Physician-scientists from Children's Hospital of Philadelphia presented updated efficacy and safety data on Kymriah--the first-ever U.S. Food and Drug Administration approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers at the 60th American Society of Hematology annual meeting, as well as first-of-its-kind research on overcoming CAR T-cell resistance.

5 Dec 2018

DFG is establishing 10 new Collaborative Research Centers to support top-level research in Germany

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing ten new Collaborative Research Centers (CRCs) to further support top-level research in Germany.

30 Nov 2018

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

From January 1, 2019, the German Research Foundation will be funding the new Collaborative Research Center 1361 on Regulation of DNA Repair & Genome Stability.

29 Nov 2018

Revolutionary new technology sheds light on why cancers form in specific cell types

While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms.

29 Nov 2018

New study solves longstanding mystery in innate immunity

UT Southwestern biochemist and Breakthrough Prize winner Dr. Zhijian "James" Chen's newest study answers a long-standing question in the field of innate immunity.

29 Nov 2018

Antibiotics can effectively target and eliminate senescent cells

ANTIBIOTICS have emerged as potentially lifespan-enhancing drugs, according to the results of new research carried out in the UK.

28 Nov 2018

Scientists identify key component of microscopic machinery that drives cell death

An important component of the microscopic machinery that drives cell death has been identified by Walter and Eliza Hall Institute scientists.

27 Nov 2018

Human brain may stay active for hours after death

One question that has baffled mankind is “after-death experience” or the experience after the heart stops beating.

25 Nov 2018

Researchers elucidate infection process of bacterial pathogen Clostridium difficile

Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells, thus destroying the protective mucosal barrier of the intestinal tract.

21 Nov 2018

Researchers discover new information on pathological mechanisms of Alzheimer's disease

Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer's disease.

20 Nov 2018

Cell Death News and Research

Simple protocol rescues stressed liver cells

Study reveals how Parkinson's disease protein 'buys time' for cell repair

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Immune cells explode themselves to inform about the danger of invading bacteria

Weakened metabolism of immune T cells may account for serious complications in elderly

New substance could improve efficacy of established breast cancer treatments

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

Sacrificial immune cells alert body to infection

Researchers gain new insights into pediatric tumors

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

DFG is establishing 10 new Collaborative Research Centers to support top-level research in Germany

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

Revolutionary new technology sheds light on why cancers form in specific cell types

New study solves longstanding mystery in innate immunity

Antibiotics can effectively target and eliminate senescent cells

Scientists identify key component of microscopic machinery that drives cell death

Human brain may stay active for hours after death

Researchers elucidate infection process of bacterial pathogen Clostridium difficile

Researchers discover new information on pathological mechanisms of Alzheimer's disease

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

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Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics