Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Monoamine neurotransmitters such as serotonin and dopamine play important roles in our cognitive and emotional functions.

5 Aug 2022

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution.

4 Aug 2022

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers.

4 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

To investigate the long-term benefit of hormone-lowering treatment, researchers at Karolinska Institutet in Sweden have done a 20-year follow-up of premenopausal women with breast cancer.

2 Aug 2022

Würzburg scientists are working on the development of new drugs to combat monkeypox

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows.

1 Aug 2022

What is the role of vitamin D in pandemic H1N1 influenza and SARS-CoV-2 infection?

A recent study published in Nutrients found that vitamin D is vital for lung protection from viral infection.

1 Aug 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Researchers describe the evolution of the SARS-CoV-2 non-structural protein 1 (NSP1).

28 Jul 2022

Innovative technology reveals new insights into cellular reservoirs of HIV

In a presentation today at AIDS 2022, the 24th International AIDS Conference in Montreal, scientists with the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC) and their collaborators described how their use of cutting-edge technology revealed new insights into cellular reservoirs of HIV and what those observations could mean for the next steps in HIV cure research. NIAID is part of the National Institutes of Health.

27 Jul 2022

Latest advancements in space health and medicine

When astronauts go to outer space, microgravity, intense cosmic radiation and extreme cold can have negative impacts on their bodies and health. Scientists want to better understand the intricate details of what happens to humans in space, and they're trying to come up with ways to counteract these effects.

25 Jul 2022

Gene Expression News and Research

Further Reading

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Research progress on the three-dimensional interaction between virus and host genome

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Terminally exhausted T cells may remain competent for transcription, researchers say

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Study provides new insight into the cellular and molecular biology of human heart failure

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

Würzburg scientists are working on the development of new drugs to combat monkeypox

What is the role of vitamin D in pandemic H1N1 influenza and SARS-CoV-2 infection?

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Innovative technology reveals new insights into cellular reservoirs of HIV

Latest advancements in space health and medicine

Using genome editing to expand the possibilities of entomological research

Study may help overcome some obstacles to the development of nanoparticle-based drugs

Pigment epithelium-derived factor ablations may lead to eye aging

Study offers insight into the basic cellular pathologies driving interstitial lung disease

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy