Genetic News and Research

RSS

Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

Researchers used drug-target Mendelian randomization to test whether genetically proxied activation of GLP1R and GIPR influences alcohol-related behaviors. They found that GIPR, especially when combined with GLP1R, was linked to lower binge and heavy drinking, healthier food preferences, improved liver markers, and reduced coronary artery disease risk.

15 Sep 2025

Smoking raises the risk of all subtypes of type 2 diabetes

The characteristics of type 2 diabetes vary from patient to patient and it has been proposed that the condition is made up of four subtypes. Now, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that smoking increases the risk of the condition, regardless of subtype.

13 Sep 2025

Rice University team develops tool to track protein aggregation hot spots

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

13 Sep 2025

Unlocking hidden soil microbes for new antibiotics

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

13 Sep 2025

Simple AI model matches dermatologist expertise in assessing squamous cell carcinoma

A simple AI model has been shown to perform on a par with experienced dermatologists when assessing the aggressiveness of a common form of skin cancer, squamous cell carcinoma. The research was headed by the University of Gothenburg.

13 Sep 2025

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.

13 Sep 2025

Blocking immune brake protein boosts defense against Aspergillus fumigatus

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus.

11 Sep 2025

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes.

11 Sep 2025

New genetic test redefines diagnosis and management of hereditary pancreatitis

A new genetic test developed at Mayo Clinic is redefining how clinicians diagnose and manage hereditary pancreatitis.

11 Sep 2025

Mapping the evolutionary trajectory of meningiomas at single-cell resolution

Meningiomas are the most common primary brain tumors, accounting for nearly one-third of all central nervous system (CNS) tumors.

11 Sep 2025

CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

11 Sep 2025

Infection or stressful events during pregnancy may increase anxiety risk in offspring

Increased risk for anxiety may begin before birth, shaped by infection or stressful events during pregnancy, according to a new preclinical study from researchers at Weill Cornell Medicine.

11 Sep 2025

New funding opportunities aim to advance bipolar disorder research

Today, Breakthrough Discoveries for thriving with Bipolar Disorder (BD²) announced the opening of a fourth round of funding opportunities for the Discovery Research program. BD² invites scientists across all disciplines to apply for up to $4.5 million per grant.

11 Sep 2025

Genes play an active role in shaping the gut bacteria, study finds

New research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.

10 Sep 2025

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

10 Sep 2025

Chronic insomnia linked to faster cognitive decline and brain changes

People with chronic insomnia may experience faster declines in memory and thinking skills as they age-along with brain changes that can be seen on imaging scans-than people who do not have chronic insomnia, according to a study published in the September 10, 2025, issue of Neurology, the medical journal of the American Academy of Neurology.

10 Sep 2025

Targeting telomere damage offers new path to boost cancer immunotherapy

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

10 Sep 2025

Rare ABCA7 gene variants linked to Alzheimer’s risk

A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to the development of Alzheimer's in some of the people who carry it.

10 Sep 2025

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of Nature that tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy

10 Sep 2025

Long-read sequencing uncovers massive DNA elements shaping human oral microbiome

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection.

10 Sep 2025