Lungs News and Research

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SARS-CoV-2 omicron variant shown to replicate less efficiently in human lungs

A new study revealed that the omicron variant replicates more effectively in the human bronchus than other SARS-CoV-2 variants, yet this new variant has lower replication competence in the lungs.

2 Feb 2022

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

Using best practice guidelines, they developed a mixed-effects deep learning model to classify images as healthy or COVID-19 accurately.

2 Feb 2022

Children are more exposed to microplastics than adults, says expert

Plastic breaks down into microplastics and even smaller nanoplastics. These plastics can be found almost everywhere around the globe.

1 Feb 2022

New RNA therapies for the treatment of heart failure and organ fibrosis

RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based compounds is far from being fully tapped, as RNA allows for entirely new therapeutic approaches.

1 Feb 2022

Patients with severe COVID-19 may have lower oxygen requirements than previously believed

A new study, led by researchers at Uppsala University, shows that all individual patients suffering from severe COVID-19 may have lower oxygen requirements than was formerly believed. The study was conducted at a Swedish district hospital during the first wave of the pandemic in 2020.

1 Feb 2022

Scientists discover new insights about lymphangioleiomyomatosis

Researchers have discovered new insights about lymphangioleiomyomatosis (LAM), a rare lung disease, which affects about 1 in 200,00 Americans and commonly features the growth of abnormal cells in different tissues and organs, including the lungs.

1 Feb 2022

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

31 Jan 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

In a new study, a team of researchers developed YF-S0, an exceptionally potent COVID-19 vaccine candidate using live-attenuated yellow fever vaccine YF17D as a vector.

31 Jan 2022

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Scientists have recently detected and analyzed viral PrDs in the S protein of SARS-CoV-2, which are the novel regulators of virion assembly.

31 Jan 2022

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Minks may be a suitable animal model for testing severe COVID-19 infections, finds a recent bioRxiv* preprint study. While mice and ferrets are used in preclinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is currently no model specific to severe disease.

30 Jan 2022

Review highlights lack of research data on health effects of nano- and microplastics on fetuses, newborns

A new, international review conducted by researchers reveals that there is not enough research data on what kind of health effects nano- and microplastics have on newborn babies, or during pregnancy and childhood.

29 Jan 2022

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

A new study investigates the association between the immune system and respiratory complications post-COVID-19 infection.

28 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear.

27 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

The analysis of more than 3,000 lung transplants in the U.S. between Aug. 1, 2020, and Sept. 30, 2021, showed that during the pandemic, 7% of the nation's lung transplants were performed to treat severe, irreversible lung damage caused by COVID-19. More than half of these patients needed ventilators or extracorporeal membrane oxygenation, or ECMO, before their transplant.

27 Jan 2022

Lungs News and Research

SARS-CoV-2 omicron variant shown to replicate less efficiently in human lungs

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

Assessing an intranasal lentiviral booster against COVID-19 variants

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

Children are more exposed to microplastics than adults, says expert

New RNA therapies for the treatment of heart failure and organ fibrosis

Patients with severe COVID-19 may have lower oxygen requirements than previously believed

Scientists discover new insights about lymphangioleiomyomatosis

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Researchers identify genetic cause of rare interstitial lung disease in a young child

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Review highlights lack of research data on health effects of nano- and microplastics on fetuses, newborns

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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