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SARS-CoV-2 Delta variant-induced antibody response largely focuses on class 1 and 2 antibody epitopes

A new study evaluated the specificity of antibody response elicited by the Delta variant of SARS-CoV-2.

18 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

New PCR test uses molecular beacons to identify the specific variant causing COVID-19 infection

After the start of the SARS-C0V-2 pandemic, investigators from ResearchPath LLC and their collaborators at Rutgers University quickly dedicated resources to develop accurate and reliable COVID-19 testing.

17 Mar 2022

Why does the SARS-CoV-2 Omicron variant escape immunity?

Researchers reveal the underlying mechanism associated with the Omicron variant’s increased transmissibility and ability to evade immunity.

17 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Researchers assessed the efficacy of vesicular stomatitis virus-based coronavirus disease 2019 vaccines in Syrian golden hamsters.

17 Mar 2022

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Researchers used molecular surveillance to identify cases of co-infection with SARS-CoV-2 variants of concern Delta and Omicron reported in Argentina during December 2021 and January 2022.

17 Mar 2022

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Researchers identify a gene that could prevent Parkinson’s disease

Parkinson's disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons.

17 Mar 2022

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

Researchers used a novel mathematical model to simulate SARS-CoV-2 dynamics inside the host.

17 Mar 2022

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Researchers assessed the safety profile and immunogenicity of a heterologous NVSI-06-08 boost against SARS-CoV-2 variants in individuals doubly vaccinated with the inactivated vaccine BBIBP-CorV.

17 Mar 2022

Novel oncogenic gene fusions identified in lung and pancreatic cancer

A Yale Cancer Center research team has identified novel oncogenic gene fusions in lung and pancreatic cancer, as well as sarcoma.

16 Mar 2022

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

Researchers determined the immune signature of the multisystem inflammatory syndrome in children among hospitalized children diagnosed with SARS‐CoV‐2 infection.

16 Mar 2022

Mason scientists receive DOD funding for breast cancer prevention and treatment research

George Mason University College of Science announced a $1.57 million dollar grant from the Department of Defense to fund a transformative approach for breast cancer treatment developed by scientists in Mason's Center for Drug Discovery for Rare Diseases.

15 Mar 2022

Study models SARS-CoV-2 M protein monomer and dimer 3D structures

Researchers presented new structural insights about the SARS-CoV-2 membrane protein.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

Researchers conducted an in vitro analysis to assess the efficacy of monoclonal antibodies against the SARS-CoV-2 Omicron BA.2 and BA.1 variants.

14 Mar 2022

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible.

12 Mar 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Mutation News and Research

SARS-CoV-2 Delta variant-induced antibody response largely focuses on class 1 and 2 antibody epitopes

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New PCR test uses molecular beacons to identify the specific variant causing COVID-19 infection

Why does the SARS-CoV-2 Omicron variant escape immunity?

Novel screening method detects new N501T SARS-CoV-2 variant

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers identify a gene that could prevent Parkinson’s disease

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Novel oncogenic gene fusions identified in lung and pancreatic cancer

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Study models SARS-CoV-2 M protein monomer and dimer 3D structures

Using mRNA to introduce gene editor into human muscle stem cells

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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