DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Early genomic profiling improves cancer treatment outcomes

New real-world data from Providence, Illumina, and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient's diagnosis, leads to better personalized treatment and patient outcomes.

12 Nov 2024

New blood test detects early lung damage in cancer patients on targeted therapy

New study introduces a simple blood test to detect early lung damage in cancer patients receiving novel therapy with antibody-drug conjugates (ADCs), which can sometimes cause serious, even fatal, lung disease (ILD).

12 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024

Next-generation metagenomic sequencing test quickly detects any kind of pathogen

Next-generation metagenomic sequencing test developed at UCSF proves its effectiveness in quickly diagnosing almost any kind of pathogen.

12 Nov 2024

Imbalances in NET homeostasis linked to portal vein thrombosis in CHB-related decompensated cirrhosis

Portal vein thrombosis (PVT) is a challenging complication in liver cirrhosis, with no currently available sensitive diagnostic markers.

12 Nov 2024

Scientists uncover a previously unrecognized tumor suppression mechanism

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role in disease.

12 Nov 2024

MethylGPT unlocks DNA secrets for age and disease prediction

Researchers developed MethylGPT, a powerful transformer-based model that identifies DNA methylation patterns, enabling advanced age and disease prediction with clinical potential.

11 Nov 2024

Revolutionary AI predicts aging and disease from DNA patterns

Researchers developed CpGPT, a novel foundation model for DNA methylation analysis that captures sequence, positional, and epigenetic context to predict aging and disease risks. This model offers breakthroughs in imputing missing data and improving mortality and morbidity predictions.

11 Nov 2024

Study shows how a single defective BRCA1 gene accelerates cancer development

People inherit two copies of each gene - one from each parent - an evolutionary fail-safe to ensure survival even when one of them doesn't function.

11 Nov 2024

Gut microbiome changes linked to onset of rheumatoid arthritis among at-risk individuals

Findings indicate gut microbiome diversity changes precede rheumatoid arthritis, offering insights into microbial indicators for early disease detection.

11 Nov 2024

Progress in early detection and screening methods for pancreatic cancer

The evolution of pancreatic cancer screening technologies is pivotal for early detection, addressing key challenges to enhance survival rates and patient care.

11 Nov 2024

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

Breakthrough research reveals how to target malignant DNA in aggressive cancers

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

9 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

New research explores the secrets behind human culture's uniqueness

Why is human culture - the shared body of knowledge passed down across generations - so much more powerful than animal cultures?

8 Nov 2024

Advancements in liquid biopsy for detecting pancreatic incidentalomas

In recent research published in eGastroenterology, Dr. J-Matthias Löhr and colleagues provide an in-depth review of diagnostic methods for pancreatic incidentaloma - incidental findings often detected during imaging scans intended for other conditions.

8 Nov 2024