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Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A new multicenter study has shown that blinded crossover and continued follow-up of trial participants can help assess vaccine durability and potential delayed enhancement of disease.

18 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

Positive results from additional analyses of PRIDE-HD and Open-HART trials with pridopidine published in a peer-reviewed journal, The Journal of Huntington's Disease.

17 Dec 2020

Intensive interventions in type 2 diabetes reduce risk of cardiovascular autonomic neuropathy

Intensive interventions to reduce blood glucose and blood pressure levels in type 2 diabetes reduce the risk of developing cardiovascular autonomic neuropathy (CAN), a frequent but underdiagnosed complication of diabetes that can be life-threatening.

17 Dec 2020

Oral hormone therapy significantly alters the metabolome of postmenopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women.

16 Dec 2020

BAT advances COVID-19 vaccine candidate into phase-I clinical trial

The COVID-19 vaccine candidate (KBP-COVID-19; NCT04473690) will become one of a number of potential vaccines to have progressed beyond pre-clinical testing.

16 Dec 2020

Combination of baricitinib and remdesivir could benefit some COVID-19 patients

The combination of baricitinib, an anti-inflammatory drug, and remdesivir, an antiviral, reduced time to recovery for people hospitalized with COVID-19, according to clinical trial results published in the New England Journal of Medicine.

11 Dec 2020

Combination therapy places no greater burden on early-stage breast cancer patients

Adding an immune checkpoint inhibitor to the standard chemotherapy regimen for patients with early-stage breast cancer places no greater burden on patients' ability to perform day-to-day activities than chemotherapy alone, new research by Dana-Farber/Brigham and Women's Cancer Center investigators shows.

10 Dec 2020

Fan therapy may offer relief for patients with advanced cancer experiencing breathlessness

Blowing air from a fan into the face of patients with advanced cancer experiencing breathlessness, and other nonpharmacologic interventions, may offer symptom relief, according to new research directed by Johns Hopkins Kimmel Cancer Center investigators.

10 Dec 2020

Hydroxychloroquine found ineffective as post-exposure SARS-CoV-2 prophylaxis

Now, a study on the utility of hydroxychloroquine as prophylaxis against COVID-19, has been released in the latest issue of Annals of Internal Medicine.

10 Dec 2020

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

As part of its Wave 1 Pipeline Market Opportunity Call, Takeda Pharmaceutical Company Limited provided an update on its pipeline portfolio, which has the potential to contribute significantly to revenue growth for the company over the next decade.

From Takeda 10 Dec 2020

Researchers examine effectiveness of treating acute infectious diarrhea with probiotics

There is no evidence that probiotics are effective in treating acute infectious diarrhoea, state the authors of this Cochrane review update. Previous editions of the review had suggested they were; but a review update of the evidence, which included new trials, has overturned the review's previous findings.

9 Dec 2020

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

Despite the encouraging news of potentially successful COVID-19 vaccine trials, there is not yet an FDA-approved vaccine available. Research into other effective coronavirus vaccines continues, including at UC Davis Health.

8 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Secukinumab for treatment of plaque psoriasis in children: Added benefit not proven

The monoclonal antibody secukinumab is approved for the treatment of moderate to severe plaque psoriasis in children and adolescents from the age of six years who are candidates for systemic therapy.

5 Dec 2020

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Affecting almost 600,000 people worldwide every year, and with only a 50% survival rate, oral squamous cell carcinoma (OSCC) is one of the more common and deadly forms of cancer.

4 Dec 2020

New antiviral drug completely suppresses SARS-CoV-2 transmission within 24 hours

Treatment of SARS-CoV-2 infection with a new antiviral drug, MK-4482/EIDD-2801 or Molnupiravir, completely suppresses virus transmission within 24 hours, researchers in the Institute for Biomedical Sciences at Georgia State University have discovered.

3 Dec 2020

Medically active component of cannabis does not impact driving ability, study shows

A landmark study on how cannabis affects driving ability has shown that cannabidiol (CBD), a cannabis component now widely used for medical purposes, does not impair driving, while moderate amounts of the main intoxicating component tetrahydrocannabinol (THC) produce mild driving impairment lasting up to four hours.

1 Dec 2020

KU Leuven vaccine candidate works against yellow fever and SARS-CoV-2 infection

Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate against Covid-19 based on the yellow fever vaccine, which as a result also works against yellow fever. Results published today in Nature show that the vaccine protects hamsters from infection with the SARS-CoV-2 coronavirus after a single dose.

1 Dec 2020

Marinomed plans a clinical trial with Carragelose nasal spray as COVID-19 prophylaxis

Marinomed Biotech AG, a globally operating biopharmaceutical company, is pleased to announce today that the Swansea University Medical School plans a clinical trial with Iota-/kappa-carrageenan nasal spray as a COVID-19 Prophylaxis for Healthcare Professionals (ICE-COVID).

30 Nov 2020

Placebo News and Research

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A protein may be responsible for triggering lung scarring in scleroderma patients

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

Intensive interventions in type 2 diabetes reduce risk of cardiovascular autonomic neuropathy

Oral hormone therapy significantly alters the metabolome of postmenopausal women

BAT advances COVID-19 vaccine candidate into phase-I clinical trial

Combination of baricitinib and remdesivir could benefit some COVID-19 patients

Combination therapy places no greater burden on early-stage breast cancer patients

Fan therapy may offer relief for patients with advanced cancer experiencing breathlessness

Hydroxychloroquine found ineffective as post-exposure SARS-CoV-2 prophylaxis

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

Researchers examine effectiveness of treating acute infectious diarrhea with probiotics

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Secukinumab for treatment of plaque psoriasis in children: Added benefit not proven

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

New antiviral drug completely suppresses SARS-CoV-2 transmission within 24 hours

Medically active component of cannabis does not impact driving ability, study shows

KU Leuven vaccine candidate works against yellow fever and SARS-CoV-2 infection

Marinomed plans a clinical trial with Carragelose nasal spray as COVID-19 prophylaxis

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