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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

AvantGen and ACROBiosystems sign vendor agreement

AvantGen Inc., a world-leading CRO for human and rabbit antibody discovery and optimization, and ACROBiosystems Inc., a global biotech company specializing in recombinant protein technology jointly announced the signing of a preferred vendor agreement between the parties.

From ACROBiosystems 7 Mar 2019

Bacteria from seawater provide new leads to treat malignant melanoma

Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads for an entirely new way to treat the disease.

7 Mar 2019

CAR-T cell therapy could be on the horizon for patients with lupus

Researchers have developed a novel CAR-T cell therapy that can reduce B cell numbers known to cause the inflammatory responses in lupus.

7 Mar 2019

Better regulation of the immune system may help manage preeclampsia

Boosting the body's levels of interleukin-4 (IL-4)--an immune system protein that controls inflammation--may help manage the pregnancy complication preeclampsia, according to a new rodent study.

7 Mar 2019

Study uses AI to analyze risk factors in type 1 diabetes

In combination with conventional statistical methods, artificial intelligence has now been used in a study of risk factors in type 1 diabetes. The objective was to identify the most important indicators of elevated risk for cardiovascular disease and death.

6 Mar 2019

Diabetes' sworn enemy could also be a protective asset

Montreal research team unravels an adaptive mechanism involved in controlling insulin action, showing that glucagon plays a crucial part in it and can thus be a protective asset.

6 Mar 2019

Fasting-mimicking diet changes gut microbiota to reduce IBD pathology in mice

Dietary modifications are frequently used to treat inflammatory bowel diseases.

6 Mar 2019

EAF4 module determines physicochemical, biophysical attributes of monoclonal antibodies

Postnova Analytics Inc. reports how its Electrical Asymmetrical Flow Field Flow Fractionation and Size Exclusion Chromatography modules have been used to determine the physicochemical and biophysical attributes of monoclonal antibodies.

From Postnova Analytics 6 Mar 2019

Discovery of protein, lipid connection could lead to new influenza therapies

The connection between an influenza virus surface protein and a host cell lipid has been discovered by researchers at the University of Maine and the National Institutes of Health. Confirmation of direct interaction between the protein and lipid could lead to new antiviral therapies.

6 Mar 2019

New mathematical method to map cell regulatory networks

Faster results. Lower costs. Fewer cells. A new mathematical method developed by researchers at Cincinnati Children's and New York University may soon make it much easier to conduct more of the complex data analysis needed to drive advances in the exploding field of personalized medicine.

6 Mar 2019

Low-calorie 'fasting-mimicking' diet has potential to treat people with IBD

What if a special diet could reduce inflammation and repair your gut? USC researchers provided evidence that a low-calorie "fasting-mimicking" diet has the potential to do just that.

6 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

New approach to creating 'theranostics' for targeting specific tumors, diseases

A City of Hope scientist and his colleagues have developed a user-friendly approach to creating "theranostics" - therapy combined with diagnostics - that target specific tumors and diseases.

6 Mar 2019

The presence of cancer-causing contaminant in popular foods

Acrylamide is described as 'extremely hazardous' and 'probably carcinogenic to humans'. Its presence in popular foods, including fried, baked, roasted and toasted potato and cereal products, as well as coffee, has become one of the most difficult issues facing the food industry, its supply chain, retailers and regulators.

5 Mar 2019

Colon cancer could be made more aggressive by common oral bacteria

Scientists have identified a common oral bacterium that accelerates colon cancer growth. The discovery could pave the way for new treatments.

5 Mar 2019

Study unravels microscopic mysteries in the brains of C. elegans

It's the small pieces that make the big picture, and in this case, the pieces can't be seen by the naked eye. New research at the Okinawa Institute of Science and Technology Graduate Universit used microscopy techniques to piece together the brain of the millimeter-long Caenorhabditis elegans, revealing that their neurons fire action potentials - a spike in voltage due to neurons sending sensory information in the cell membrane.

5 Mar 2019