Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Concrete proof that public smoking bans work

At a major international conference in Edinburgh, Scotland, experts from around the world were given concrete proof that public smoking bans are effective when it comes to health benefits.

11 Sep 2007

New minimally-invasive coated vascular stent graft in use at Methodist DeBakey Heart Center

Surgeons at the Methodist DeBakey Heart Center in Houston were among the first in the U.S. to implant a new, less-invasive stent graft designed to reduce the risk of blood clots in patients treated for peripheral arterial disease (PAD), which affects as many as 12 million Americans over the age of 50.

11 Sep 2007

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Therapies leading to longer life for HIV patients have paradoxically increased the prevalence of this condition. Identifying biological markers for the development of HIV–associated dementia is critical both for diagnosing the disorder and for understanding its underlying mechanisms.

11 Sep 2007

Being overweight may independently increase risk for developing coronary heart disease

Being moderately overweight or obese appears to increase the risk for developing coronary heart disease events independent of traditional cardiovascular risk factors, according to a meta-analysis of previously published studies in the September 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11 Sep 2007

Nuclear medicine approach can be first choice for excluding pulmonary embolism in young women

Young women at risk of having a pulmonary embolism - a potential life-threatening blockage in a lung artery - should first undergo a ventilation/perfusion lung scan (V/Q scan) rather than a CT (computed tomography) angiogram, conclude authors in a paper published in the September Journal of Nuclear Medicine.

10 Sep 2007

Improved dosing formula for warfarin (Coumadin)

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients.

5 Sep 2007

Fat: An active player in the regulation of many processes in health and disease

Why should we be interested in doing obesity-related research? Emphasis is put on this type of research simply because of the fact that the epidemiological data and predictions are alarming. Worldwide it is estimated that one person in every eight is overweight and more than 300 millions are obese

3 Sep 2007

OPTIMIST: The Outcome of PCI for stent-ThrombosIs MultIcentre STudy

Stent thrombosis is a recognized complication occurring in 1-2% of patients with coronary artery disease treated by percutaneous coronary intervention (PCI) with stent implantation. Its occurrence is expected to increase with the number of stent implantation procedures done worldwide. Moreover, stent thrombosis is a hot topic in the cardiology community.

3 Sep 2007

Genetic-based dosing in orthopedic patients beginning warfarin therapy

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients. But now the process can be faster and safer, thanks to research conducted at Washington University School of Medicine in St. Louis.

3 Sep 2007

Patent foramen ovale (PFO) and atrial septal defect (ASD) closure

A PFO and an ASD are congenital structural heart diseases characterized by a communication between heart chambers at the level of the wall (septum) separating them. These chambers are the left and right atrium as shown on the picture below. The right atrium receives (dark) oxygen-depleted blood from the great veins, while the left atrium receives (red) oxygen-rich blood from the lungs.

3 Sep 2007

Immediate emergency angioplasty can save the lives of those experiencing MI

We have demonstrated that patients who have an acute myocardial infarction and are admitted to a hospital which has no possibility to perform direct angioplasty, benefit from being transferred immediately after having received thrombolytics to a hospital where angioplasty (percutaneous coronary intervention, PCI, often including stent implantation) can be immediately performed.

3 Sep 2007

How to optimally prepare a patient for planned coronary angiography and subsequent angioplasty?

A Czech study compared two anti-clotting treatment regimens, currently used before coronary angiography / angioplasty to find the optimal balance between preventing ischemic versus bleeding complications of these procedures. The study was conducted in five Czech tertiary cardiology centers.

3 Sep 2007

DES: friend or foe?

The current FDA approved stents (CYPHER and TAXUS) have been associated with late stent thrombosis (LST) (>30days following implantation) however, the mechanisms predictive of LST are poorly understood. Pathologic studies are one of the best methods for detailed analysis of morphologic changes that occur after placement of Drug Eluting Stents to determine the causes of LST.

3 Sep 2007

Long term follow up of additional Swedish registry data does not indicate an increased

Four years of follow up including additional patients in the Swedish Coronary angiography and angioplasty registry (SCAAR) does no longer indicate any increased mortality in patients treated with drug eluting stents compared to patients treated with bare metal stents.

2 Sep 2007

New evidence links discontinuation of statin therapy to increased death rates in stroke survivors

Patients who stop taking cholesterol-lowering drugs within a year of surviving a stroke had a two-fold increased risk of death, researchers reported in Stroke: Journal of the American Heart Association.

30 Aug 2007

Inhaling nitric oxide helps transplant success

Administering inhaled nitric oxide (NO) during surgery helps protect liver transplant patients from organ failure, according to a new study from researchers at the University of Alabama at Birmingham (UAB).

30 Aug 2007

Protein on the surface of platelets plays a key role in cancer-induced platelet aggregation

Scientists have provided new details about how cancer cells spread by surrounding themselves with platelets – the blood cells needed for blood clotting.

30 Aug 2007

Stroke outcome improves when patients continue taking cholesterol-lowering drugs

A new study has illustrated the risks involved when statin treatment is discontinued after a stroke and shows an increased risk of death or dependency is present for up to 90 days.

29 Aug 2007

FDA approves Evithrom (human thrombin)

The U.S. Food and Drug Administration has approved Evithrom (human thrombin), a blood-clotting protein used to help control bleeding during surgery.

28 Aug 2007

Statin drugs should be continued after stroke

People who stopped taking cholesterol-lowering drugs after being hospitalized for a stroke are at greater risk of death or dependency within three months of the stroke, according to a study published in the August 28, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

28 Aug 2007

Blood Clot News and Research

Further Reading

Concrete proof that public smoking bans work

New minimally-invasive coated vascular stent graft in use at Methodist DeBakey Heart Center

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Being overweight may independently increase risk for developing coronary heart disease

Nuclear medicine approach can be first choice for excluding pulmonary embolism in young women

Improved dosing formula for warfarin (Coumadin)

Fat: An active player in the regulation of many processes in health and disease

OPTIMIST: The Outcome of PCI for stent-ThrombosIs MultIcentre STudy

Genetic-based dosing in orthopedic patients beginning warfarin therapy

Patent foramen ovale (PFO) and atrial septal defect (ASD) closure

Immediate emergency angioplasty can save the lives of those experiencing MI

How to optimally prepare a patient for planned coronary angiography and subsequent angioplasty?

DES: friend or foe?

Long term follow up of additional Swedish registry data does not indicate an increased

New evidence links discontinuation of statin therapy to increased death rates in stroke survivors

Inhaling nitric oxide helps transplant success

Protein on the surface of platelets plays a key role in cancer-induced platelet aggregation

Stroke outcome improves when patients continue taking cholesterol-lowering drugs

FDA approves Evithrom (human thrombin)

Statin drugs should be continued after stroke

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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