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Scientists discover role for vitamin D in melanoma

A new study published in Cancer Research suggests that high levels of vitamin D may reduce the aggressive nature of melanoma cells and improve survival rates.

8 Nov 2019

New model could predict response of HIV-infected individuals to cancer immunotherapy

A group of researchers at UPF and the Marchuk Institute of Numerical Mathematics in Moscow, Russia, have designed a mathematical model to predict the response of HIV-infected individuals to a type of cancer immunotherapy.

7 Nov 2019

Scientists discover structure of novel RNA-modifying enzyme

RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme, ZCCHC4, and identified the mechanism that controls how this enzyme recognizes its substrate.

6 Nov 2019

New therapy has potential to repair cells damaged by noise, prevent hearing loss

More than 700 million people worldwide suffer from some degree of hearing loss, including an estimated 20 percent of Americans over the age of 12, according to medical experts.

6 Nov 2019

Study: Spherical exosomes could help in treating acute kidney injury

Like a swarm of construction workers in the aftermath of a destructive storm, cargo-filled, nanometer-sized spheres arrive on the scene following an acute kidney injury.

5 Nov 2019

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

The University of Texas MD Anderson Cancer Center and Takeda Pharmaceutical Company Limited today announced an exclusive license agreement and research agreement to develop cord blood-derived chimeric antigen receptor-directed natural killer (CAR NK)-cell therapies, 'armored' with IL-15, for the treatment of B-cell malignancies and other cancers.

5 Nov 2019

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

Eisai Co., Ltd. announced today that it has entered into an agreement to transfer the rights to receive royalties on the sales outside of Japan for an investigational anti-cancer agent tazemetostat (generic name) to Royalty Pharma.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Scientists capture elusive cancer-related protein in action

Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell.

4 Nov 2019

Some skin cancers originate in hair follicles, says new study

A new study published online in Nature Communicationson November 4, 2019, reports that some melanomas, which are among the deadliest skin cancers, originate in melanocyte stem cells that are located within the hair follicles.

4 Nov 2019

Good news, bad news: lower antibiotic use, more antibiotic resistance in UK

Public Health England (PHE) is cheering about a significant fall in the number of antibiotic prescriptions in England over the five years between 2014 and 2019, when it has dropped by 17%. However, with more and more bacterial infections showing antibiotic resistance every single year, there is no room for complacency.

31 Oct 2019

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

An international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differentiation of neurons.

30 Oct 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Scientists uncover how brain cells respond to and recover from lack of nutrition

We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly how early brain growth is affected by nutrition is not as well understood, especially on a cellular level.

25 Oct 2019

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Sarcomas - cancers that arise from transformed mesenchymal cells (a type of connective tissue) - are quite deadly. Gastrointestinal stromal tumors are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

Scientists take new step toward the goal of growing cell-based meat for human consumption

A team of Tufts University-led researchers exploring the development of cultured meat found that the addition of the iron-carrying protein myoglobin improves the growth, texture and color of bovine muscle grown from cells in culture.

22 Oct 2019

Link between pregnancy stress, immune activation, and postpartum depression

A new study presented at the Society for Neuroscience meeting on October 19, 2019, at Chicago, shows for the first time how postpartum depression could actually be due to abnormal immune system activation within the brain, which in turn is set off by chronic pregnancy stress. This is the earliest study to show this link in animals.

22 Oct 2019

Koalas protect their germline cells against retroviral attack

In a new study published in the journal Cell, scientists have found that koala DNA is protected against attack by retroviruses by a special type of immune response, which distinguishes foreign DNA from the host genome and destroys it before it can proliferate. This finding could help us understand both how koalas survive these infections, and the mechanics of adaptive gene change.

15 Oct 2019

Glycans in mucus are responsible for microbe-taming, study reveals

More than 200 square meters of our bodies -- including the digestive tract, lungs, and urinary tract -- are lined with mucus. In recent years, scientists have found some evidence that mucus is not just a physical barrier that traps bacteria and viruses, but it can also disarm pathogens and prevent them from causing infections.

14 Oct 2019

Proliferation News and Research

Scientists discover role for vitamin D in melanoma

New model could predict response of HIV-infected individuals to cancer immunotherapy

Scientists discover structure of novel RNA-modifying enzyme

New therapy has potential to repair cells damaged by noise, prevent hearing loss

Study: Spherical exosomes could help in treating acute kidney injury

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

Humanizing cell cultures

Scientists capture elusive cancer-related protein in action

Some skin cancers originate in hair follicles, says new study

Good news, bad news: lower antibiotic use, more antibiotic resistance in UK

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

New cellular immunotherapy for cancers

Scientists uncover how brain cells respond to and recover from lack of nutrition

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Scientists take new step toward the goal of growing cell-based meat for human consumption

Link between pregnancy stress, immune activation, and postpartum depression

Koalas protect their germline cells against retroviral attack

Glycans in mucus are responsible for microbe-taming, study reveals

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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