Immune System News and Research

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Immune system produces neutralizing antibodies capable of blocking HIV, says study

Scientists seeking to understand how to make an AIDS vaccine have found the cause of a major roadblock. It turns out that the immune system can indeed produce cells with the potential to manufacture powerful HIV-blocking antibodies - but at the same time, the immune system works equally hard to make sure these cells are eliminated before they have a chance to mature.

16 Dec 2009

Infectious virus particles can bind to the surface of red blood cells: MHRP researchers

Free infectious HIV-1 is widely thought to be the major form of the virus in the blood of infected persons. U.S. Military HIV Research Program (MHRP) researchers, however, have demonstrated that essentially all of the infectious virus particles can bind to the surface of red blood cells isolated from each of 30 normal (non-infected) human donors.

16 Dec 2009

Drug monitoring may provide alternative treatments for patients with severe H1N1

An international team of Canadian and Spanish scientists have found the first potential immunological clue of why some people develop severe pneumonia when infected by the pandemic H1N1 virus.

16 Dec 2009

University of Missouri researchers work on immune-strengthening vaccine for newborns

As soon as babies are born, they are susceptible to diseases and infections, such as jaundice and e-coli. For up to a month, their immune systems aren't adequately developed to fight diseases. Although these infections are often minor, they can lead to serious problems if left untreated.

16 Dec 2009

U.S. patent for new bioadhesive drug delivery system awarded to SRI International

SRI International, an independent nonprofit research and development organization, announced today the award of U.S. patent 7,592,021 for a new bioadhesive drug delivery system that enables enhanced release of drugs through the human body's mucous membranes.

16 Dec 2009

Dendritic cell changes suggest new strategy to identify and treat debilitating lung disease

A new study links chronic obstructive pulmonary disease, or COPD, with increased activity of cells that act as sentinels to activate the body's immune system.

15 Dec 2009

Advaxis to collaborate with GOG in Phase II clinical trial of ADXS11-001

Advaxis, Inc., the live, attenuated Listeria monocytogenes (Lm) vaccine company, will collaborate with the Gynecologic Oncology Group (GOG), a collaborative research group of the National Cancer Institute (NCI), in a multicenter, Phase II clinical trial of the Company’s lead drug candidate, ADXS11-001 in the treatment of advanced cervix cancer in women who have failed prior cytotoxic therapy.

15 Dec 2009

Encouraging results from DAVANAT in combination with chemotherapies and biologics

Pro-Pharmaceuticals, Inc. today announced that the Brussels Branch of the Ludwig Institute of Cancer Research is testing the ability of DAVANAT® to stop Galectin-3 from blocking the immune system’s action on cancer cells. Peer reviewed studies have demonstrated that Galectin-1 and Galectin-3 induce apoptosis (cell death) in immune system T cells (“Galectins,” Chapter 7, Wiley, 2008).

15 Dec 2009

Cellular and subcellular effects of PACE technology presented

SANUWAVE Health, Inc., (www.sanuwave.com), an emerging medical technology company focused on the development and commercialization of non-invasive, biological response activating devices in the regenerative medicine area, announced that the cellular and subcellular effects of PACE™ technology were described during a lecture presented this past weekend.

15 Dec 2009

Lytix Biopharma AS receives approval to commence Phase I clinical trials of Oncopore

The Norwegian pharmaceutical company Lytix Biopharma AS today announced approvals from the Norwegian Medicines Agency (”Statens legemiddelverk”) and the Swedish Medical Products Agency (”Läkemedelverket”) to commence Phase I clinical trials of OncoporeTM (LTX-315) for the treatment of cancer.

15 Dec 2009

Freie Universität professor receives ERC grant for bacterial biofilm formation study

Prof. Dr. Regine Hengge at the Department of Biology, Chemistry, and Pharmacy at Freie Universität Berlin has been awarded funding from the European Research Council (ERC) for her research project to investigate the formation of bacterial biofilms. Hengge will receive an ERC Advanced Investigator Grant in an amount of up to two million euros.

15 Dec 2009

Supplements boost immune system and offer protection against seasonal flu

Accompanied by a chorus of coughs and sniffles, the winter season has arrived. "Protecting your health during this year's winter season should be a top priority for people," said Tom Tolworthy, CEO and Chief Health Enthusiast for The Vitamin Shoppe. "Many of our customers are being proactive in boosting their immune systems this time of year."

15 Dec 2009

RORalpha protein revealed as an essential regulator of inflammatory factors

How do the brain cells called astrocytes ensure the protection of neurons? By studying the protagonists in the protection and satisfactory functioning of neurons, scientists at the Laboratoire Neurobiologie des Processus Adaptatifs (CNRS/UPMC) have found a mechanism that clarifies the role of astrocytes.

15 Dec 2009

New highly sensitive CFSE T cell proliferation assays launched by ProImmune

ProImmune Ltd, a leader in epitope discovery, immunogenicity and immune monitoring products and services, has launched CFSE T cell proliferation assays for immunogenicity risk assessment. The new highly sensitive assays form part of ProImmune’s REVEAL Immunogenicity System, a suite of tools used in the design and selection of biological drug leads at the preclinical stage.

15 Dec 2009

Researchers to receive more than $4.5 million in grants to study Sudden Infant Death Syndrome

Researchers at the Los Angeles Biomedical Research Institute (LA BioMed) expect to receive more than $4.5 million in grants from the American Recovery and Reinvestment Act (Recovery Act.), including nearly $1 million from the highly competitive Challenge Grant program for a study that seeks to reduce the number of children who die from Sudden Infant Death Syndrome, it was announced today.

15 Dec 2009

AIDS develops more rapidly in individuals who express HLA B*35-Px, shows study

Immune proteins called HLA molecules help to activate killer T cell responses against pathogens. But according to a study that will be published online on December 14th in the Journal of Experimental Medicine (www.jem.org), one particular group of HLA molecules cripples this activation, perhaps explaining why HIV-infected individuals who express these HLAs progress to AIDS more rapidly than others.

15 Dec 2009

Modified blood adult stem-cell transplant regimen reverses sickle cell disease

A modified blood adult stem-cell transplant regimen has effectively reversed sickle cell disease in 9 of 10 adults who had been severely affected by the disease, according to results of a National Institutes of Health study in the Dec. 10 issue of the New England Journal of Medicine.

13 Dec 2009

Clinical trial of 2009 H1N1 influenza vaccine

HIV-infected adults currently are being recruited to participate in a clinical trial of 2009 H1N1 influenza vaccine. The study, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health, will enroll approximately 240 men and women between the ages of 18 and 64.

13 Dec 2009

New data suggests bisphosphonate drug may play a role in reducing recurrent breast cancer

Bisphosphonates are routinely given to women with postmenopausal breast cancer, but new data suggests that these agents may play a role in reducing recurrent breast cancer as well.

11 Dec 2009

NCKUH and NHRI sponsor virology lab in Vietnam Children’s Hospital

A Virology Lab in Children’s Hospital No. 1 (CH1), Ho Chi Minh City, Vietnam, sponsored by National Cheng Kung University Hospital (NCKUH) and National Health Research Institutes (NHRI) in Taiwan was launched on November 11th, 2009.

11 Dec 2009

Immune System News and Research

Immune system produces neutralizing antibodies capable of blocking HIV, says study

Infectious virus particles can bind to the surface of red blood cells: MHRP researchers

Drug monitoring may provide alternative treatments for patients with severe H1N1

University of Missouri researchers work on immune-strengthening vaccine for newborns

U.S. patent for new bioadhesive drug delivery system awarded to SRI International

Dendritic cell changes suggest new strategy to identify and treat debilitating lung disease

Advaxis to collaborate with GOG in Phase II clinical trial of ADXS11-001

Encouraging results from DAVANAT in combination with chemotherapies and biologics

Cellular and subcellular effects of PACE technology presented

Lytix Biopharma AS receives approval to commence Phase I clinical trials of Oncopore

Freie Universität professor receives ERC grant for bacterial biofilm formation study

Supplements boost immune system and offer protection against seasonal flu

RORalpha protein revealed as an essential regulator of inflammatory factors

New highly sensitive CFSE T cell proliferation assays launched by ProImmune

Researchers to receive more than $4.5 million in grants to study Sudden Infant Death Syndrome

AIDS develops more rapidly in individuals who express HLA B*35-Px, shows study

Modified blood adult stem-cell transplant regimen reverses sickle cell disease

Clinical trial of 2009 H1N1 influenza vaccine

New data suggests bisphosphonate drug may play a role in reducing recurrent breast cancer

NCKUH and NHRI sponsor virology lab in Vietnam Children’s Hospital

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