Animal Model News and Research

RSS

Use of anti-inflammatory drugs by children may be associated with dental enamel defects

A study conducted at the University of São Paulo in Brazil and described in an article published in the journal Scientific Reports shows that anti-inflammatory drugs commonly taken by children may be associated with dental enamel defects (DEDs), currently seen in about 20% of children worldwide.

20 Dec 2022

Probiotic bacterium prevents neurodegeneration in animal model of ALS

A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).

20 Dec 2022

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

An experimental therapy showed promise as treatment for an aggressively spreading type of colorectal cancer in preclinical models, according to a new study by Weill Cornell Medicine investigators.

16 Dec 2022

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

An international research team led by Dr Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into the mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

12 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

Study provide new insights into why cholestasis causes cognitive issues

Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline.

6 Dec 2022

Mpox virus from Clade 2b is the least virulent strain according to new study

Researchers used the CAST/EiJ mouse model to test whether genetic differences between clades 1, 2a, and 2b of the monkeypox virus contribute to changes in transmission and virulence of the disease.

5 Dec 2022

The potential of grape consumption to modulate UV-induced skin erythema

A recent Antioxidants study evaluated the effect of grape consumption on reducing UV-induced skin erythema.

2 Dec 2022

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

A Phase 2 clinical trial has started of DS-1211 in individuals with Pseudoxanthoma Elasticum (PXE), a rare multisystem genetic disease that causes calcium deposits in soft tissue resulting in considerable morbidity.

1 Dec 2022

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.

30 Nov 2022

Newly discovered material can aid healing of hard-to-treat diabetic wounds

Scientists have discovered a new material that can be applied to diabetic wounds to heal them faster with just one application.

29 Nov 2022

How does quinoa affect the gut microbiome of men?

Although a high intake of whole grain foods reduces the risk of cardiometabolic diseases, obesity, type 2 diabetes, and certain types of cancers, the underlying mechanism behind this occurrence is unclear. Whole grain foods tend to be healthier due to their high dietary fiber and phytoconstituents, typically lost during refining.

28 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

Scientists develop preclinical model of scrub typhus disease

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis, and immune responses. The study has been published in the journal PLOS Neglected Tropical Diseases.

27 Nov 2022

Animal Model News and Research

Use of anti-inflammatory drugs by children may be associated with dental enamel defects

Probiotic bacterium prevents neurodegeneration in animal model of ALS

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

Low-intensity ultrasound therapies may help rebuild stronger knees

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Study provide new insights into why cholestasis causes cognitive issues

Mpox virus from Clade 2b is the least virulent strain according to new study

The potential of grape consumption to modulate UV-induced skin erythema

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Newly discovered material can aid healing of hard-to-treat diabetic wounds

How does quinoa affect the gut microbiome of men?

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

Scientists develop preclinical model of scrub typhus disease

Combination of ultrasound and nanobubbles enables the removal of tumors without surgery

Why we should all eat Kimchi and other Korean fermented foods

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

High-intensity aerobic exercise can cut metastatic cancer risk by 72%

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News