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CRISPR technology reveals essential noncoding RNAs in the human genome

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins.

7 Nov 2024

CHiTA assay identifies functional twister ribozymes

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, like DNA, RNA can carry genetic information, but, like a protein, it can also act as an enzyme, initiating or accelerating reactions.

5 Nov 2024

Machine learning identifies key genes linking rheumatoid arthritis and osteoporosis

Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

5 Nov 2024

descendantsDNA, Inc. engages Broad Clinical Labs and Fabric Genomics for genomic services to support human longevity

descendantsDNA, Inc. is pleased to announce a new agreement with Broad Clinical Labs (BCL) to advance human longevity through cutting-edge genomics.

From Fabric Genomics 30 Oct 2024

Researchers uncover the link between EVs and tissue damage

A landmark study led by WEHI and La Trobe University has found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our bodies.

29 Oct 2024

FDA funding fuels research on turkey parasite and potential treatments

As scientists learn more about a deadly parasite's ability to move from host to host in turkey flocks, a long-standing theory is in question and opens the door to new preventative measures.

22 Oct 2024

Study reveals complex role of polyploidy in cancer and treatment resistance

Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies.

21 Oct 2024

Polyploidy can be a double-edged sword in cancer

Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies.

21 Oct 2024

Sweden exceeds UNAIDS HIV goals but faces new challenges

Sweden has surpassed the UNAIDS 95-95-95 targets, with reduced HIV incidence and a steady increase in diagnosed and treated cases. However, challenges remain, especially among migrant populations and recent arrivals.

20 Oct 2024

Genetics identified as key factor in gout development

A major international study has found gout is a chronic illness where genetics is a major cause, rather than lifestyle choices of the sufferer.

15 Oct 2024

University of Michigan receives $30 million grant to enhance genetic data storage

The University of Michigan will dramatically boost the amount and type of genetic information stored in its massive TOPMed data center and used by researchers and healthcare providers around the world looking to genomes to treat disease.

14 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024

Umeå University discovers critical mechanisms in stem cell differentiation

A study led by Umeå University, Sweden, presents new discoveries about how stem cells develop and transition into specialised cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

12 Oct 2024

Researchers uncover new mechanism of stem cell differentiation linked to cancer progression

A study led by Umeå University, Sweden, have made new discoveries about how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

12 Oct 2024

Researchers uncover key bacteria driving success of fecal microbiota transplants

Fecal microbiota transplants, or FMTs, are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why.

9 Oct 2024

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

Epigenetic hallmarks of cancer unveiled in new research

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

1 Oct 2024

Scientists unravel the process of pore formation in cells

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of inflammatory messengers.

26 Sep 2024

CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) systems.

25 Sep 2024

New approach to B-ALL treatment reduces side effects and enhances survival

Clinical trial results from St. Jude Children's Research Hospital demonstrate benefits to using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL).

24 Sep 2024