Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.

New nanomedicine device is effective for treating glioblastoma multiforme

A micro-sized polymeric net wrapping around brain tumors, just like a fishing net around a shoal of fish: this is the microMESH, a new nanomedicine device capable to conform around the surface of tumor masses and efficiently deliver drugs.

20 Apr 2021

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

20 Apr 2021

Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients

Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer.

19 Apr 2021

An ion pump tested as a possible method to treat malignant brain tumors

Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumors.

15 Apr 2021

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

April 29 marks a pivotal moment in cancer research when the world's brightest minds come together to discuss how to translate the success of CAR T-cell therapies for blood cancers into successful cell and gene therapies for the most complex and deadly solid tumor cancers.

15 Apr 2021

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer.

12 Apr 2021

Giving chemotherapy in the morning can extend survival of glioblastoma patients

An aggressive type of brain cancer, glioblastoma has no cure. Patients survive an average of 15 months after diagnosis, with fewer than 10% of patients surviving longer than five years.

31 Mar 2021

Study reveals the structure of key enzyme that may advance cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type of enzyme known as a protease.

30 Mar 2021

Novel gene therapy reprograms glioma cells into functional neurons

Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades.

24 Mar 2021

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of brain cancer.

23 Mar 2021

Doctors found jet fuel in veteran’s lungs. He can’t get full benefits.

The lungs Bill Thompson was born with told a gruesome, harrowing and unmistakable tale to Dr. Anthony Szema when he analyzed them and found the black spots, scarring, partially combusted jet fuel and metal inside.

19 Mar 2021

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life changing success of CAR-T therapies for blood cancers, the organization is now focused on the urgent need to translate this success into therapies to fight more types of cancer, such as solid tumor cancers.

19 Mar 2021

UAB researchers find potential new pathway to treating radiation-resistant glioblastoma

Researchers at the University of Alabama at Birmingham have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer.

15 Mar 2021

Immune-modified ex vivo platform can measure treatment response of ovarian cancer

KIYATEC, Inc researchers demonstrated that their immune-modified ex vivo platform can measure treatment response through direct interaction between a patient's cancer and infiltrating immune cells, and immuno-oncology agents.

12 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

Three projects from University of Colorado Cancer Center receive grants for brain tumor research

Three projects from University of Colorado Cancer Center researchers have received grants from the Denver-based Michele Plachy-Rubin Fund for Pilot Grants in Brain Cancer Research. Receiving $40,000 each to fund their work around brain cancer are Sujatha Venkataraman, PhD; and the teams of Philip Reigan, PhD, and Michael Graner, PhD; and Natalie Serkova, PhD, and Nicholas Foreman, MD, MBChB.

10 Mar 2021

ACGT awards $500,000 to advance immunotherapy approach for treating solid tumors

A scientific team led by Brian Brown, PhD, Professor of Genetics and Genomic Sciences and Associate Director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai (New York, New York), has been awarded $500,000 from Alliance for Cancer Gene Therapy to advance a promising immunotherapy approach to fight lung cancer and other solid tumor cancers.

1 Mar 2021

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