Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Campus voices: Should student health centers offer abortion pills?

Forty-five years after Roe v. Wade made abortions legal, a growing number of states — and the federal government — are restricting access to them.

12 Mar 2018

Ibuprofen intake could be leading to male infertility

According a new study that appeared this week in the journal Proceedings of the National Academy of Sciences, simple pain reliever, Ibuprofen, could be having a problematic effect on the testes of young men. Ibuprofen is taken almost routinely by young athletes for injuries and pain.

9 Jan 2018

Stopping opioid addiction at one key source: The hospital

It may not be rocket science, but a group of surgeons at the University of Michigan's Michigan Medicine have devised a strategy to curb the nation's opioid epidemic — starting at their own hospital.

6 Dec 2017

Guidelines to control opioid prescribing for post-surgery pain

A recent study, conducted at Dartmouth-Hitchcock Medical Center in Lebanon, NH, suggests that more vigilant prescribing guidelines could reduce the number of opioid pills a patient receives after surgery, whilst still meeting pain management needs.

1 Dec 2017

New study tests pain treatment in humans

Nerve growth factor signals through receptors of the tropomyosin-related kinase (Trk) family, and research in animals has shown that inhibitors of Trks A, B, and C can reduce pain.

27 Nov 2017

One in 20 children still receiving codeine to treat pain despite warning from federal regulators

A new study shows as many as one in 20 children were still receiving codeine to treat pain after tonsil and adenoid surgery, two years after federal regulators warned doctors that prescribing the opioid to kids after the routine surgeries could be fatal.

16 Nov 2017

Review looks into conventional versus new treatment modalities in orthodontic pain management

Patients experience pain and discomfort during active orthodontic treatment with fixed appliances. It can vary from person to person and is influenced by certain factors such as age, gender, previous pain experiences, stress or anxiety, and type of appliance.

16 Nov 2017

New drug offers hope for osteoarthritis patients suffering from debilitating hand pain

Osteoarthritis is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function.

13 Nov 2017

Scientists to investigate potential role of airborne pollutants as triggers of Parkinson's disease

The Department of Defense has awarded a multi-institutional team of scientists a series of grants totaling $4.37 million to investigate the potential role of airborne pollutants as triggers of Parkinson's disease via the nose.

9 Nov 2017

Gut bacteria composition could predict toxicity of chemotherapy drugs in cancer patients

Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal cancer.

1 Nov 2017

Sanford Health to evaluate effectiveness of non-opioid medications

Sanford Health is one of three sites in the U.S. to launch a study to determine if non-opioid medications are as effective in managing pain after carpal-tunnel surgery.

30 Oct 2017

Bariatric surgical patients may be vulnerable to opioid dependence

Nearly 9 percent of bariatric surgical patients--or about one in 12--who did not take opioid pain medications until their weight-loss operation, or the month before it, report that they are still using prescription opioids one year postoperatively, according to new research findings.

24 Oct 2017

Opioid-free anesthesia reduces postoperative nausea, study finds

Opioid-free general anesthesia is safe, effective and dramatically decreases postoperative nausea, according to a single-center study of more than 1,000 patients being presented at the ANESTHESIOLOGY 2017 annual meeting.

24 Oct 2017

Fever in first trimester of pregnancy increases risk for birth defects, study shows

Fevers in a mother's first trimester of pregnancy increase the baby's risk for some heart defects and facial deformities such as cleft lip or palate, but exactly how this happens is unclear. Scientists have debated whether a virus or other infection causes the defects, or if fever alone is the problem.

12 Oct 2017

Clinical trial tests frankincense as potential breast, colon cancer treatment

Cancer surgeon and researcher Nancy DeMore is leading a clinical trial using frankincense to try to treat breast and colon cancer at the Medical University of South Carolina. The study was inspired by a research specialist in DeMore's lab.

11 Oct 2017

Duke researchers unravel how fever in early pregnancy increases risk for heart, facial birth defects

Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is unclear. Scientists have debated whether a virus or other infection source causes the defects, or if fever alone is the underlying problem.

10 Oct 2017

Experts advise new measures to combat antimicrobial resistance

An expert panel was formed in the United States to advise the government on how to deal with the problem of antimicrobial resistance (AMR), a growing menace. This panel has now come up with a set of recommendations that could help reduce AMR in humans and animals. Recommendations include development of new vaccines against infections, development of better diagnostic tools to detect the infections early and also new therapies to handle the infections.

22 Sep 2017

Antidepressants used for chronic pain relief come with significant side effects

Chronic pain negatively impacts a person's quality of life. Often, over the counter pain medication, such as ibuprofen or aspirin, are ineffective in alleviating chronic pain. In these instances, a surprising choice is often a drug used to treat an entirely different condition - depression.

5 Sep 2017

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

The long-term use of over-the-counter (OTC) anti-inflammatory drugs can inhibit muscle growth in young, healthy individuals engaging in weight training, according to a new study from Karolinska Institutet, reporting on the effects of ibuprofen on the skeletal muscles and published in Acta Physiologica.

28 Aug 2017

NSAIDs may not be safe for arthritis patients with cardiovascular risk, study shows

Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to late-breaking results from the PRECISION-ABPM study presented today in a Hot Line Session at ESC Congress and published in EHJ.