Malignant News and Research

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Advancing diagnostic accuracy in soft tissue cytopathology through WHO guidelines

Soft tissue cytopathology plays a vital role in the diagnosis and management of soft tissue neoplasms, necessitating a standardized classification system to improve diagnostic accuracy and guide clinical decision-making.

18 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

AI tool predicts tumor aggressiveness using protein markers

As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment.

15 Jul 2025

Microplastics found to trigger cancer-linked changes in lung cells

Although the respiratory system is one of the main entry points for microplastics and nanoplastics (MNPs) from the air into the body, little is known about the effects of these tiny particles on the lungs.

15 Jul 2025

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

14 Jul 2025

Understanding the human brain architecture through gene coexpression analysis

In a comprehensive Genomic Press Interview published in Brain Medicine, Dr. Michael C. Oldham shares his unconventional journey from advertising executive to computational neuroscientist and his groundbreaking contributions to understanding the human brain's cellular and molecular architecture through gene coexpression analysis.

8 Jul 2025

AI assistance improves accuracy and consistency in skin cancer tissue analysis

Pathologists' examinations of tissue samples from skin cancer tumors improved when they were assisted by an AI tool. The assessments became more consistent and patients' prognoses were described more accurately.

4 Jul 2025

Probiotics improve ovarian damage in premature menopausal mice

Findings suggest probiotics could mitigate ovarian decline and improve microbiota in POI mice, paving the way for new treatments in women's health.

4 Jul 2025

Experimental medication sensitizes glioblastoma to treatment and blocks tumor spread

A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain cancer newly sensitive to both radiation and chemotherapy drugs, and blocks the cancer's ability to invade other tissue, a new study shows.

2 Jul 2025

Breakthrough study reveals killing power of CD4 T cells against cancer

In the fight against cancer, immunotherapy - which aims to boost the body's natural defences against cancer - is experiencing remarkable growth. Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells.

1 Jul 2025

AI system outperforms dermatologists in diagnosing facial pigmented lesions

A research team led by Haruyo Yamamoto, Chisa Nakashima, and Atsushi Otsuka from Department of Dermatology, Kindai University Faculty of Medicine, in collaboration with the Faculty of Engineering at Kindai University and other institutions, has developed a diagnostic system that uses artificial intelligence (AI) to accurately identify the type of facial pigmented lesions and support laser treatment decisions.

1 Jul 2025

Caltech researchers develop safer and smarter breast imaging technique

A Caltech-led team has developed a safe, effective, and painless breast imaging technique that incorporates machine learning to help differentiate between suspicious and healthy tissue.

30 Jun 2025

FAU researchers secure key grants to target new gene in the fight against glioblastoma

Florida Atlantic University researchers have secured two key grants to investigate targeting a gene for the first time as a new approach to treat glioblastoma, a very aggressive and fast-growing type of brain cancer.

30 Jun 2025

Risk factors associated with emergency presentations following malignant skin cancer

Emergency department (ED) presentations are associated with higher cancer mortality. This study aimed to investigate the prevalence, frequency, and risk factors in Australian patients diagnosed with malignant skin cancers.

27 Jun 2025

Organ chip technology accurately predicts chemotherapy response in esophageal adenocarcinoma patients

Esophageal adenocarcinoma (EAC), one of two major forms of esophageal cancer, is the sixth most deadly cancer worldwide for which no effective targeted therapy exists.

27 Jun 2025

Newly discovered target may re-energize exhausted immune cells in the fight against cancer

Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or "exhausted" immune cells in their fight against cancer.

27 Jun 2025

FAM111B identified as a key driver of glioma progression and therapeutic target

Gliomas are among the deadliest brain tumors, with limited treatment options and poor survival rates. Scientists from China identified FAM111B, a DNA-repair-associated protein, as a key driver of glioma progression.

27 Jun 2025

Meningiomas more common in older women than previously known

Tumors of the meninges are more common in older women than previously known. In a study from the University of Gothenburg, 2.7 percent of 70-year-old women had such tumors. The researchers emphasize that such findings should be treated with diligence and careful consideration.

26 Jun 2025

Lower post-meal blood sugar linked to reduced mortality risk

It is well known that preventing the onset of diabetes reduces the risk of death, and that managing blood glucose levels is key to preventing diabetes.

25 Jun 2025

TET1 identified as key regulator in cancer and chronic disease

Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases.

25 Jun 2025

Malignant News and Research

Advancing diagnostic accuracy in soft tissue cytopathology through WHO guidelines

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

AI tool predicts tumor aggressiveness using protein markers

Microplastics found to trigger cancer-linked changes in lung cells

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

Understanding the human brain architecture through gene coexpression analysis

AI assistance improves accuracy and consistency in skin cancer tissue analysis

Probiotics improve ovarian damage in premature menopausal mice

Experimental medication sensitizes glioblastoma to treatment and blocks tumor spread

Breakthrough study reveals killing power of CD4 T cells against cancer

AI system outperforms dermatologists in diagnosing facial pigmented lesions

Caltech researchers develop safer and smarter breast imaging technique

FAU researchers secure key grants to target new gene in the fight against glioblastoma

Risk factors associated with emergency presentations following malignant skin cancer

Organ chip technology accurately predicts chemotherapy response in esophageal adenocarcinoma patients

Newly discovered target may re-energize exhausted immune cells in the fight against cancer

FAM111B identified as a key driver of glioma progression and therapeutic target

Meningiomas more common in older women than previously known

Lower post-meal blood sugar linked to reduced mortality risk

TET1 identified as key regulator in cancer and chronic disease

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