Nitric Oxide News and Research

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New drug offers hope for preserving brain cells for a time after stroke

After 50 years of research and the testing of over 1,000 drugs, there is new hope for preserving brain cells for a time after stroke.

21 Feb 2020

New understanding of neurovascular coupling

A new study published in the journal Nature in February 2020 reports the discovery of a control mechanism in mouse brains, which makes it possible to sensitively regulate the flow of blood to different areas of the brain, to supply enough to more active areas.

19 Feb 2020

Long-term consumption of lingonberry juice lowers high blood pressure, study finds

An experimental study found that long-term consumption of lingonberry juice lowers high blood pressure and improves the function of blood vessels.

3 Jan 2020

Study shows abnormal cardiovascular response to nitroglycerin in migraine patients

A clinical investigation recently published in the journal Cephalalgia, the official journal of the International Headache Society, suggests that migraine patients may exhibit a systemic pathophysiological alteration.

28 Dec 2019

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Only few nutritional supplements provide protection against cardiovascular disease

Store shelves are filled with nutritional supplements that promise to help with everything from joint pain to lowering cholesterol. Despite those claims, only three supplements have been shown to provide some protection against cardiovascular disease.

27 Nov 2019

Research finds particular subclass of 'bad cholesterol' is a much better predictor of heart attacks

New research at Ohio University shows that a particular subclass of low-density lipoproteins (LDL), also known as "bad cholesterol," is a much better predictor of potential heart attacks than the mere presence of LDL, which is incorrect more often than not.

18 Nov 2019

High-salt diet may trigger dementia

We’ve all heard that taking too much salt can damage your blood vessels, and now a new study published in the journal Nature on October 23, 2019, says it’s true – a diet rich in salt reduces the levels of nitric oxide, which in turn alters the tau protein within the neuron, triggering a fall in cognitive processing by the brain.

24 Oct 2019

High levels of dietary salt can activate a brain pathway to cause cognitive impairment

High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, which was published in Nature, shows that this effect is not due to a loss in blood flow to the brain as originally thought, but rather to clumps of a protein linked to several forms of dementia in humans.

23 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

New link between two important products of nitric oxide discovered

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.

4 Oct 2019

Researchers create pain mediator profile for pancreatic diseases

In a recent study, a team at the Technical University of Munich (TUM) discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the nerves of the organ in high concentrations.

2 Oct 2019

Mouthwash impacts the effects of exercise

Scientists have long known that the blood pressure drops after exercise but the mechanism has not been fully elucidated. A new study shows that bacteria in the mouth, which produce nitrite, is key to the whole process. The use of mouthwash to reduce the number of these bacteria prevents the expected benefit of exercise on the blood pressure.

4 Sep 2019

Ohio University scientists win $1.7 million grant for research on non-melanoma skin cancers

The National Institute of Environmental Health Sciences has awarded Ohio University scientists Shiyong Wu and Lingying Tong a five-year $1.7 million grant to advance research on a potential prevention and treatment for non-melanoma skin cancers.

20 Aug 2019

New study finds increase in erectile function after consumption of nuts

A recent study, partially supported by the INC and published in the journal Nutrients, observed a significant increase in erectile function after the consumption of 60 g/day of nuts.

29 Jun 2019

New discovery may explain some forms of stroke

Scientists from the University of Sheffield have discovered a novel behavior of the blood vessels of the brain in zebrafish that may explain some forms of stroke in humans.

23 Jun 2019

Researchers develop NO-scavenging hydrogel for treatment of rheumatoid arthritis

Nitric oxide (NO) prevents high blood pressure and artery plaque build-up in our body. However, its duplicity is shown when it causes serious inflammatory disease such as systemic lupus erythematosus, Cronh's disease, and rheumatoid arthritis.

4 Jun 2019

The two-hit model can lead to better understanding of heart failure

Nearly half of current hospital admissions for heart failure are caused by a type of the disease with no treatment options. Cardiology researchers at UT Southwestern Medical Center are changing that reality with a fresh approach, recently published in Nature.

12 Apr 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019