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MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

The Muscular Dystrophy Association today announced the award of 34 new grants totaling more than $9.9 million for its summer round of funding. These new grants represent a continued commitment by MDA to fund groundbreaking research that will accelerate treatments and cures for the more than 40 diseases in its program.

24 Aug 2018

Study provides new clues to connection between aging and neurodegeneration

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases.

23 Aug 2018

Electrical stimulation of the brain may help treat symptoms of neurodegenerative ataxias

Electrical stimulation of the brain and spinal cord may help treat the symptoms of rare movement disorders called neurodegenerative ataxias, according to a study published in the August 22, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Aug 2018

Researchers discover new subtype of multiple sclerosis

Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis, providing a better understanding of the individualized nature of the disease.

22 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Researchers reveal insights into how body clock controls inflammatory response

Researchers at RCSI and Trinity College Dublin have revealed insights into how the body clock controls the inflammatory response, which may open up new therapeutic options to treat excess inflammation in conditions such as asthma, arthritis and cardiovascular disease.

21 Aug 2018

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

Seeking solutions to treat scleroderma

It begins with cold hands. Not just put-on-some-gloves cold. Instead, the fingers overreact to cold by turning white or blue and may become numb or tingly.

17 Aug 2018

Study shows link between thinning of the retina and early sign of Parkinson's disease

The eyes may be a window to the brain for people with early Parkinson's disease. People with the disease gradually lose brain cells that produce dopamine, a substance that helps control movement.

16 Aug 2018

‘No one is ever really ready’: Aid-in-dying patient chooses his last day

In the end, it wasn't easy for Aaron McQ to decide when to die. The 50-year-old Seattle man — a former world traveler, triathlete and cyclist — learned he had leukemia five years ago, followed by an even grimmer diagnosis in 2016: a rare form of amyotrophic lateral sclerosis, or ALS.

14 Aug 2018

Long-term cannabinoid exposure impairs memory, study shows

A new study led by Ana Sebastião, group leader at Instituto de Medicina Molecular João Lobo Antunes and Professor of Faculdade de Medicina of Universidade de Lisboa and her team in collaboration with researchers from the University of Lancaster, shows that the long-term use of either cannabis or cannabis-based drugs impairs memory.

13 Aug 2018

PARP inhibitors show promise for treating and preventing brain disorders

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis, also called Lou Gehrig's disease, and some forms of frontotemporal degeneration, by halting the misplacement of specific proteins that affect nerve cells, according to a study published in Molecular Cell by researchers in the the School of Arts and Sciences and the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2018

Collaboration between Merck and InnoCore could improve biologic drug delivery

Following today’s (Friday 3 August) announcement of Merck and InnoCore’s collaboration, Rahael Maladwala, Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on what this might mean for biologic drug delivery:

10 Aug 2018

New combination therapy for cancer cells could soon be a reality

A new cancer therapy using nanoparticles to deliver a combination therapy direct to cancer cells could be on the horizon, thanks to research from the University of East Anglia.

From Precision NanoSystems Inc. 10 Aug 2018

Atlas of the nervous system provides new clues about origin of neurological diseases

Researchers at Karolinska Institutet have created a systematic and detailed map of the cell types of the mouse nervous system.

9 Aug 2018

New guideline released to improve diagnosis, care for people with prolonged disorders of consciousness

For people in a vegetative or minimally conscious state caused by brain injury, an accurate diagnosis and ongoing medical and rehabilitative care based on the latest scientific evidence could mean a better chance for recovery, according to a new guideline by the American Academy of Neurology, American Congress of Rehabilitation Medicine and the National Institute on Disability, Independent Living, and Rehabilitation Research.

9 Aug 2018

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

7 Aug 2018

Researchers report new way to map the inner workings of a living cell

Imaging tools like X-rays and MRI have revolutionized medicine by giving doctors a close up view of the brain and other vital organs in living, breathing people. Now, Columbia University researchers report a new way to zoom in at the tiniest scales to track changes within individual cells.

6 Aug 2018

Clinical trial to use stem cell transplants for treating Crohn's disease

A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn's disease - a painful and chronic intestinal disease which affects at least 115,000 people in the UK.

6 Aug 2018

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Metabolomics is the latest omics systems science technology with emerging applications towards psychiatry, personalized medicine, and most recently, precision nutrition research.

3 Aug 2018