Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Study suggests vitamin D supplements may decrease insulin resistance, fight depression

A daily dose of vitamin D may just be what Chicagoans need to get through the long winter, according to researchers at Loyola University Chicago Marcella Niehoff School of Nursing (MNSON). This nutrient lifts mood during cold weather months when days are short and more time is spent indoors.

4 Mar 2010

Not getting enough sleep can cause fat to accumulate around organs, say researchers

Not getting enough sleep does more damage than just leaving you with puffy eyes. It can cause fat to accumulate around your organs - more dangerous, researchers say, than those pesky love handles and jiggly thighs.

2 Mar 2010

Using genetic engineering techniques in pigs, scientists create new model of diabetes

The incidence of diabetes is rising worldwide. Using genetic engineering techniques in pigs, scientists at Ludwig-Maximilians-Universität in Munich have created a new model of this metabolic disorder, which recapitulates many features of the disease, and promises to contribute significantly to improvements in diagnosis and therapy.

1 Mar 2010

Inadequate sleep may lead to increase in belly fat

A study in the March 1 issue of the journal SLEEP shows that African-American and Hispanic young adults with short or long sleep durations had greater increases in belly fat over a five-year period compared with those who reported sleeping six to seven hours a night.

1 Mar 2010

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

Women who gain excessive weight during pregnancy, especially in the first trimester, may increase their risk of developing diabetes later in their pregnancy, according to a study by the Kaiser Permanente Division of Research that appears online in the current issue of Obstetrics and Gynecology.

23 Feb 2010

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate.

16 Feb 2010

p62 and ERK proteins lead to development of obesity and insulin resistance, say scientists

New research by University of Cincinnati scientists implicates a new protein in obesity development and highlights a protein pair's "team effort" in regulating obesity and insulin resistance.

15 Feb 2010

White rye flour bread leads to better insulin and blood sugar levels than wheat bread with rye bran

Wholegrain bread is good and good for you, as most people know. But it is not only the fiber-rich bran, the outer shell of the grain, that is healthful. On the contrary, research at the Lund University Faculty of Engineering shows that bread baked with white rye flour, which is flour made from the inner, white part of the rye kernel, leads to better insulin and blood sugar levels compared with wheat bread with rye bran. White rye flour thus leads to much better values than both regular wheat flour and rye bran. At the same time, much of the bread that is sold in stores today in most countries is in fact baked with wheat flour and bran from various grains.

12 Feb 2010

Center for Adolescent Bariatric Surgery performs 100th LAGB procedure

Few treatments are available to help obese adolescents who are unable to lose weight and are already suffering from obesity-related health problems. Laparoscopic adjustable gastric banding (LAGB), an option for adults in the United States since 2001, is showing promise for teens. The Center for Adolescent Bariatric Surgery, which opened at NewYork-Presbyterian Morgan Stanley Children's Hospital in 2006, recently performed its 100th LAGB procedure.

12 Feb 2010

$TZD drug may increase fracture risk in older women$

TZD drug may increase fracture risk in older women

A Henry Ford Hospital study finds women with type 2 diabetes who take a commonly prescribed class of medications to treat insulin resistance may be at a higher risk for developing bone fractures.

10 Feb 2010

Researchers uncover new mechanism to protect individuals from serious complications of obesity

Although obesity is a risk factor for diabetes and coronary heart disease worldwide, only some obese individuals go on to develop these metabolic complications, while others are relatively protected. Defining these protective factors could help scientists prevent disease in the wider population.

4 Feb 2010

Study: Fat tissue in women with PCOS produces inadequate amount of hormone

Fat tissue in women with Polycystic Ovary Syndrome produces an inadequate amount of the hormone that regulates how fats and glucose are processed, promoting increased insulin resistance and inflammation, glucose intolerance, and greater risk of diabetes and heart disease, according to a study conducted at the Center for Androgen-Related Research and Discovery at Cedars-Sinai Medical Center.

3 Feb 2010

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Repros Therapeutics Inc. today announced that the Company has received verbal confirmation from the Division of Metabolic and Endocrine Drug Products of the Food and Drug Agency that the Company may initiate its Investigational New Drug Application for the study of oral Androxal® in the treatment of hypogonadal men with Type II Diabetes (T2D) with a Phase IIa trial.

3 Feb 2010

Fat tissue in PCOS patients may predispose them to diabetes and heart disease

3 Feb 2010

Women's metabolic disorder remains largely undiagnosed

Gail Donnelly's classmates nicknamed her "Knobby" because she was so skinny all her bones seemed to poke out from under her skin. But when Donnelly turned 27, that once knobby frame disappeared under mysteriously ballooning weight.

2 Feb 2010

Research could help in developing more specific treatments for Type 2 diabetes

New research on Type 2 diabetes by Trinity College Dublin researchers could benefit young adults (aged 18-25 years) with the condition. The research led by Professor John Nolan of Trinity College Dublin and St James's Hospital, Dublin, has just been published online in the leading international journal, Diabetes Care.

2 Feb 2010

Obesity and type 2 diabetes in younger people can increase risk of stroke and heart attack

People who are obese and have type 2 diabetes in their 20s will be at higher risk of having a heart attack or stroke in their 40s if they do not change their lifestyle.

30 Jan 2010

Health benefits of aerobics can be greatly affected by what you eat after exercise

Many of the health benefits of aerobic exercise are due to the most recent exercise session (rather than weeks, months and even years of exercise training), and the nature of these benefits can be greatly affected by the food we eat afterwards, according to a study published in the Journal of Applied Physiology (http://jap.physiology.org).

29 Jan 2010

Alli boosts weight loss and reduces excess visceral fat

New studies show that overweight and obese people using alli® (orlistat 60 mg) with a reduced calorie, lower-fat diet can significantly reduce weight, visceral fat, and waist circumference and therefore may reduce their risk of type 2 diabetes, hypertension, heart disease and stroke.

28 Jan 2010

GENFIT's GFT505 exhibits potential to address unmet needs in prediabetic and diabetic patients

GENFIT, a biopharmaceutical company at the forefront of drug discovery and development, focusing on the early diagnosis and preventive treatment of cardiometabolic and neurodegenerative diseases, today announces positive results from a recently completed clinical trial demonstrating the activity of GFT505 on glucose homeostasis. Results from the clinical trial (GFT505-2094) clearly demonstrate the potential of the drug candidate to reduce global cardiovascular risk in prediabetic patients who suffer from impaired fasting plasma glucose, impaired glucose tolerance, and abdominal obesity.

28 Jan 2010

Insulin Resistance News and Research

Further Reading

Study suggests vitamin D supplements may decrease insulin resistance, fight depression

Not getting enough sleep can cause fat to accumulate around organs, say researchers

Using genetic engineering techniques in pigs, scientists create new model of diabetes

Inadequate sleep may lead to increase in belly fat

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

p62 and ERK proteins lead to development of obesity and insulin resistance, say scientists

White rye flour bread leads to better insulin and blood sugar levels than wheat bread with rye bran

Center for Adolescent Bariatric Surgery performs 100th LAGB procedure

TZD drug may increase fracture risk in older women

Researchers uncover new mechanism to protect individuals from serious complications of obesity

Study: Fat tissue in women with PCOS produces inadequate amount of hormone

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Fat tissue in PCOS patients may predispose them to diabetes and heart disease

Women's metabolic disorder remains largely undiagnosed

Research could help in developing more specific treatments for Type 2 diabetes

Obesity and type 2 diabetes in younger people can increase risk of stroke and heart attack

Health benefits of aerobics can be greatly affected by what you eat after exercise

Alli boosts weight loss and reduces excess visceral fat

GENFIT's GFT505 exhibits potential to address unmet needs in prediabetic and diabetic patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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