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VEGF family biomarkers ‘promising’ tools for pulmonary hypertension diagnosis

Two members of the vascular endothelial growth factor family are highly specific and moderately sensitive for the presence of pulmonary hypertension, report researchers.

10 Sep 2015

Signs of Alzheimer’s found in growth hormone patients

People may be able to contract Alzheimer’s disease during certain medical procedures in the same way that Creutzfeldt-Jakob disease (CJD) is transmitted, suggest researchers from University College London.

10 Sep 2015

Innovative vaccine therapy shows promise against glioblastoma brain tumors

An innovative vaccine therapy developed at Roswell Park Cancer Institute is being tested in a multisite clinical trial involving 50 patients with newly diagnosed glioblastoma brain tumors. The phase II study, now accruing patients at both Roswell Park and the Cleveland Clinic, will assess the effectiveness of the SurVaxM vaccine in combination with standard chemotherapy as treatment for this often-fatal cancer.

10 Sep 2015

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

Alzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death among the elderly and the leading cause of dementia. Predictions are that the number of AD cases will quadruple by 2050.

9 Sep 2015

MU researchers identify age-related cause of arterial dysfunction

With the world's elderly population expected to double by 2050, understanding how aging affects the body is an important focus for researchers globally. Cardiovascular disease, the No. 1 cause of death worldwide, often is associated with aging arteries that restrict blood flow. Now, University of Missouri researchers have identified an age-related cause of arterial dysfunction, a finding that could lead to future treatments for some forms of vascular disease.

9 Sep 2015

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

A research group at Umeå University in Sweden, together with researchers in Munich, have identified two enzymes from the pathogenic Legionella bacteria that are very useful in chemically modifying proteins to be used in medical drugs. The result of the study is presented in the chemical journal Angewandte Chemie International Edition.

7 Sep 2015

14th APS symposium highlights role of endothelin in many biological functions

Endothelin (ET) is a peptide produced by cells in the blood vessels and has powerful vessel-constricting effects. Although endothelin is mainly associated with its role in blood pressure control and cardiovascular diseases, it continues to appear in other physiological functions and diseases.

4 Sep 2015

New treatments under development for adults with coeliac disease may also benefit children

A new study has revealed childhood coeliac disease mirrors the condition in adults, increasing the possibility a coeliac disease therapy that could enable patients to eat gluten again will work in children.

4 Sep 2015

Altering protein recycling complexes in human cells may help overcome chemotherapy resistance

Altering the protein recycling complexes in human cells, including cancer cells, allows the cells to resist treatment with a class of drugs known as proteasome inhibitors, according to Whitehead Institute scientists.

2 Sep 2015

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

In heart failure patients with diabetes and/or chronic kidney disease, a new, non-steroidal mineralocorticoid receptor antagonist (MRA) called finerenone was no more effective than the currently approved MRA eplerenone in reducing the heart failure biomarker N-terminal pro-B-type natriuretic peptide [NT-proBNP].

1 Sep 2015

Breakthrough discovery provides better understanding of Alzheimer’s disease

Alzheimer's disease is associated with the appearance of characteristic neurotoxic protein aggregates in various regions in the brain.

1 Sep 2015

New book provides authoritative overview of neuroendocrine tumors

Neuroendocrine tumors (NETs) originate from diffuse neuroendocrine cells that are dispersed throughout the body, predominantly in the gastrointestinal tract, islets of Langerhans in the pancreas and the bronchopulmonary system.

31 Aug 2015

ELIXA trial results demonstrate cardiovascular safety of lixisenatide drug

In patients with type 2 diabetes and acute coronary syndrome, the glucose-lowering medication lixisenatide did not increase or decrease the rate of cardiovascular (CV) events compared to placebo, according to results of the Evaluation of Lixisenatide in Acute Coronary Syndrome (ELIXA) trial.

31 Aug 2015

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

When it comes to treating high blood pressure, not all anti-hypertensive medications are equal, and results of the ATTEMPT-CVD trial suggest that telmisartan, an angiotensin II receptor blocker (ARB) might have benefits over non-ARB treatment.

31 Aug 2015

UiO researchers test new nasal spray device for treating mental illness

Researchers at the University of Oslo have tested a new device for delivering hormone treatments for mental illness through the nose. This method was found to deliver medicine to the brain with few side effects.

27 Aug 2015

MorphoSys, Immatics partner to develop novel antibody-based therapies against multiple proprietary cancer antigens

MorphoSys AG and Immatics Biotechnologies GmbH announced today a strategic alliance to generate novel antibody-based therapeutics against multiple proprietary cancer antigens recognized by T cells.

26 Aug 2015

UA professor uses NSF grant to develop 3-D-printed biodegradable polymer scaffolds

Laboratory-engineered noses, jaws and ears. The stuff science fiction is made of is coming soon from a University of Akron lab. With a $390,000 NSF grant, Matthew Becker, UA professor of polymer science and biomedical engineering, is developing 3-D-printed biodegradable polymer scaffolds, the frameworks within which bone will grow, with the hope of changing the face of craniofacial reconstruction.

25 Aug 2015

Esperance, MD Anderson form strategic alliance to accelerate development of anti-cancer candidate EP-100

Esperance Pharmaceuticals Inc. today announced that it has entered into a strategic alliance agreement with MD Anderson Cancer Center to accelerate the clinical development of its lead anti-cancer candidate EP-100 for the treatment of ovarian cancer and to collaborate on preclinical studies of EP-100 as a treatment for breast cancer.

24 Aug 2015

Researchers report new breakthrough in countering deadly effects of radiation exposure

An interdisciplinary research team led by The University of Texas Medical Branch at Galveston reports a new breakthrough in countering the deadly effects of radiation exposure. A single injection of a regenerative peptide was shown to significantly increase survival in mice when given 24 hours after nuclear radiation exposure.

24 Aug 2015

Surprising mechanism behind antibiotic resistant bacteria uncovered by TSRI scientists

Every year, more strains of bacteria develop resistance to the antibiotics we use to treat deadly infections. At The Scripps Research Institute (TSRI) scientists have been working to develop new forms of these drugs, including an antibiotic called arylomycin—but tests have shown that it is possible for bacteria to become resistant to arylomycin, too.

20 Aug 2015

Peptides News and Research

VEGF family biomarkers ‘promising’ tools for pulmonary hypertension diagnosis

Signs of Alzheimer’s found in growth hormone patients

Innovative vaccine therapy shows promise against glioblastoma brain tumors

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

MU researchers identify age-related cause of arterial dysfunction

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

14th APS symposium highlights role of endothelin in many biological functions

New treatments under development for adults with coeliac disease may also benefit children

Altering protein recycling complexes in human cells may help overcome chemotherapy resistance

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

Breakthrough discovery provides better understanding of Alzheimer’s disease

New book provides authoritative overview of neuroendocrine tumors

ELIXA trial results demonstrate cardiovascular safety of lixisenatide drug

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

UiO researchers test new nasal spray device for treating mental illness

MorphoSys, Immatics partner to develop novel antibody-based therapies against multiple proprietary cancer antigens

UA professor uses NSF grant to develop 3-D-printed biodegradable polymer scaffolds

Esperance, MD Anderson form strategic alliance to accelerate development of anti-cancer candidate EP-100

Researchers report new breakthrough in countering deadly effects of radiation exposure

Surprising mechanism behind antibiotic resistant bacteria uncovered by TSRI scientists

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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