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Comparing lateral flow testing with RT-PCR to detect SARS-CoV-2

Lateral flow devices (LFDs) are point-of-care tests that require significantly more time to develop than RT-PCR assays but can be used locally with minimal to no training, some of which can provide results in as little as 30 minutes. However, there have been some worries about the sensitivity of such kits. As a result, researchers from Micropathology Ltd have been comparing the two methods.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

A recent study compares the transmissibility of the SARS-CoV-2 Alpha and Delta variants in six states across New England in the United States

11 Oct 2021

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

A new study assesses antibody and functional T-cell responses at 6 months after complete vaccination with the Pfizer-BioNTech vaccine.

11 Oct 2021

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

A new study finds that plasmonic sensing of LAMP amplicons through DNA hybridization enables highly specific detection of SARS-CoV-2 RNA.

11 Oct 2021

Acquisition of Advanced Diagnostic Laboratory LLC

ADL Health’s CLIA-certified laboratory covers the fields of clinical, forensic and microbiological tests.

From EKF Diagnostics 11 Oct 2021

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

A new study introduces the possibility that the inactivated polio vaccine can elicit antibodies that inhibit SARS-CoV-2 nucleic acid synthesis.

10 Oct 2021

Qatari study finds BNT162b2 vaccine effectiveness waning 6 months after second dose

The researchers assessed the effectiveness of the BNT162b2 vaccine against SARS-CoV-2 infection and COVID-19-related hospitalization and deaths.

10 Oct 2021

Study shows an association between initial SARS-CoV-2 viral load and disease severity

Researchers investigated the utility of initial SARS-CoV-2 viral loads of tests performed at a Public Health testing facility regarding hospital and ICUs admissions and overall survival.

8 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Graphene biosensor in a portable and wireless device for rapid SARS-CoV-2 detection

A new study posted to the medRxiv* server and led by Dr. Mattia D'Agostino, Dr. Eleonora Pavoni and Dr. Alice Romagnoli from the Polytechnic University of Marche in Ancona (Italy), a gFET biosensor that uses angiotensin-converting enzyme 2 (ACE2) as a bioreceptor has been put forth as a viable solution.

6 Oct 2021

Enisamium shows potential as antiviral therapy for COVID-19

Researchers studied the effect of enisamium on the growth and proliferation of Caco-2 and normal human bronchial epithelial cells.

6 Oct 2021

Rapid molecular assay to detect SARS-CoV-2-specific RNA sequences

The study reported rapid detection of SARS-CoV-2 with high sensitivity and specificity in clinical samples.

6 Oct 2021

Transmission of SARS-CoV-2 during a 2-hour domestic flight

A new study investigated a cluster of COVID-19 infections among travelers who were likely exposed to an index patient in an airplane.

6 Oct 2021

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

A new study reports on the results of phase III clinical trial on the safety and efficacy of the AstraZeneca-Oxford COVID-19 vaccine.

5 Oct 2021

Anti-nucleocapsid SARS-Cov-2 antibodies wane over time in long-term care facilities

A new study shows that up to a third of survivors in LTCFs were infected during the first year after infection.

5 Oct 2021

What makes SARS-CoV-2 variants more virulent?

Researchers in the Republic of Korea have conducted a study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that could help to inform further studies investigating the increased virulence of variants of concern and interest.

4 Oct 2021

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

A new study aimed to analyze the nasopharyngeal microbiota of patients who were hospitalized with COVID-19.

4 Oct 2021

Children are less likely to get long-COVID, yet still at risk, study finds

A new study investigates the persistence of neuropsychiatric symptoms in children and adolescents several months after they tested positive for SARS-CoV-2.

3 Oct 2021

Polymerase News and Research

Comparing lateral flow testing with RT-PCR to detect SARS-CoV-2

Research reveals components of Sinbis virus ribonucleoproteins

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

Acquisition of Advanced Diagnostic Laboratory LLC

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

Qatari study finds BNT162b2 vaccine effectiveness waning 6 months after second dose

Study shows an association between initial SARS-CoV-2 viral load and disease severity

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Graphene biosensor in a portable and wireless device for rapid SARS-CoV-2 detection

Enisamium shows potential as antiviral therapy for COVID-19

Rapid molecular assay to detect SARS-CoV-2-specific RNA sequences

Transmission of SARS-CoV-2 during a 2-hour domestic flight

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

Anti-nucleocapsid SARS-Cov-2 antibodies wane over time in long-term care facilities

What makes SARS-CoV-2 variants more virulent?

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

Children are less likely to get long-COVID, yet still at risk, study finds

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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