Genetic News and Research

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Genetics and diet work together to shape daily rhythms of fat metabolism

Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism.

25 Aug 2025

Having a sense of purpose linked to lower dementia risk

Research into Blue Zones - regions of the world where people tend to live longer - shows that having a sense of purpose in life may help people live longer.

25 Aug 2025

Common painkillers ibuprofen and paracetamol found to fuel antibiotic resistance

Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we're sick. But new research from the University of South Australia shows that these trusted staples are quietly fuelling one of the world's biggest health threats: antibiotic resistance.

25 Aug 2025

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

A nationwide Korean cohort study found that antibiotic use during pregnancy or early infancy did not increase overall risk of childhood autoimmune diseases. Subgroup signals for Crohn’s disease and autoimmune thyroiditis warrant cautious follow-up.

25 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

AI tool reveals how TB drugs kill bacteria at the molecular level

Tuberculosis (TB) is the world's deadliest infectious disease—and one of the hardest to cure. Standard treatment requires a cocktail of multiple drugs over at least six months, and one in five patients have a type of TB that resists these first-line medications.

25 Aug 2025

Genetic testing of IVF-created embryos could help more women over 35 have a baby sooner

Genetic testing of IVF-created embryos could help more women over 35 have a baby in less time, a clinical trial by researchers from King's College London, King's College Hospital, and King's Fertility has found.

25 Aug 2025

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk.

25 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

22 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

Excessive amounts of visceral fat tied to faster heart aging

Excessive amounts of visceral fat - the hidden fat surrounding organs - is linked with faster aging of the heart, a new study has found.

22 Aug 2025

AI and advanced microscopy reveal tangled DNA structures with nanometer precision

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

22 Aug 2025

Computational framework deciphers cellular organization

One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes – be they organs, wings, or limbs.

22 Aug 2025

Edible microbeads trap fat to support weight loss

Weight-loss interventions, including gastric bypass surgery and drugs that prevent dietary fat absorption, can be invasive or have negative side effects.

21 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Researchers show that countries with higher initial COVID-19 vaccine acceptance also achieved stronger booster uptake, but trust and access remain decisive. The commentary warns that vaccine successes also fueled hesitancy, demanding structural reforms, clear communication, and proactive strategies to protect immunization.

21 Aug 2025

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025

Genetic News and Research

Genetics and diet work together to shape daily rhythms of fat metabolism

Having a sense of purpose linked to lower dementia risk

Common painkillers ibuprofen and paracetamol found to fuel antibiotic resistance

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

Fat location, not BMI, drives heart ageing risk in men and women

AI tool reveals how TB drugs kill bacteria at the molecular level

Genetic testing of IVF-created embryos could help more women over 35 have a baby sooner

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

How a single gene reshapes pain perception through polyamine signaling

Next-gen sequencing reveals the regulatory potential of the non-coding genome

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Excessive amounts of visceral fat tied to faster heart aging

AI and advanced microscopy reveal tangled DNA structures with nanometer precision

Computational framework deciphers cellular organization

Edible microbeads trap fat to support weight loss

Gut bacteria and insomnia influence each other in small but significant ways, study shows

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Research shows how lysosomes respond to stress

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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