Immune System News and Research

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High mutation count in new COVID-19 variants does not increase immune evasion, study finds

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

19 Jul 2024

Discovery of key RSV immune evasion mechanism offers hope for new treatments

Irish scientists led by a group from Trinity College Dublin have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an exciting new target for drug developers.

19 Jul 2024

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammaging', which is widely believed to be the root cause of many age-related diseases.

18 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Autoantibodies against type 1 interferons linked to higher susceptibility to viral disease

A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life.

18 Jul 2024

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells

Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses.

18 Jul 2024

Flu viruses can use a second entry pathway to infect cells

Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers at the University of Zurich have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells.

18 Jul 2024

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe COVID-19 pneumonia and could be used to treat other respiratory infections, according to clinical trial results from researchers at UCL, UCLH and the Francis Crick Institute.

18 Jul 2024

Acute gastroenteritis linked to higher rates of irritable bowel syndrome and functional dyspepsia

Researchers examine the prevalence of post-infectious irritable bowel syndrome and post-infectious function dyspepsia following acute gastroenteritis.

18 Jul 2024

Llama-derived molecules target hidden strains of HIV

A research team at Georgia State University has developed tiny, potent molecules that are capable of targeting hidden strains of HIV. The source? Antibody genes from llama DNA.

17 Jul 2024

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

An article published in the journal Cell describes a study that enabled a group of researchers to discover how SARS-CoV-2 evades the cytotoxic immune response by identifying a protein called ORF6 that is a key factor in this mechanism.

16 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Immune System News and Research

High mutation count in new COVID-19 variants does not increase immune evasion, study finds

Discovery of key RSV immune evasion mechanism offers hope for new treatments

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Autoantibodies against type 1 interferons linked to higher susceptibility to viral disease

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells

Flu viruses can use a second entry pathway to infect cells

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

Acute gastroenteritis linked to higher rates of irritable bowel syndrome and functional dyspepsia

Llama-derived molecules target hidden strains of HIV

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Researchers discover key functions of IRF1 in cancer progression and treatment response

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Drastic caloric restriction by athletes diminishes performance and compromises the immune system

COVID-19 leads to long-term changes in the immune system, study shows

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

UQ study offers insights into how Haemophilus influenzae manipulates the immune system

Immune cell inflammation may be responsible for some severe symptoms in lysosomal storage diseases

Leveraging antibodies as a drug delivery mechanism may prove useful in the treatment of cancers

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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