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World’s first HIV-to-HIV kidney transplant with living donor succeeds

The world's first kidney transplant from a living HIV-positive donor to another HIV-positive person was successfully performed Monday by doctors at a Johns Hopkins University hospital.

28 Mar 2019

U of G study beginning to unravel mystery of hagfish’s zombie hearts

They are the scavengers of the deep and the dead. Hagfish are slimy bottom-dwellers that live off the carcasses of dead sea creatures and thrive in deep waters where oxygen is hard to come by. In fact, their hearts can keep on beating for 36 hours without any oxygen, making hagfish a champion among anoxia-tolerant fish.

28 Mar 2019

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Anti-TB drugs can increase susceptibility to Mtb reinfection

Current treatments for tuberculosis are very effective in controlling TB infection caused by Mycobacterium tuberculosis. They don't, however, always prevent reinfection. Why this happens is one of the long-standing questions in TB research.

22 Mar 2019

Surprising discovery offers clues to limit graft-vs.-host disease

A protein that protects people with inflammatory bowel disease has quite a different effect in graft-vs.-host disease, a common and challenging side effect of bone marrow transplants.

22 Mar 2019

Study provides new insight into blood cell and immune cell production

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system.

22 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

Novel cardiac pump shows superior outcomes in patients with advanced heart failure

Severely ill patients with advanced heart failure who received a novel heart pump—the HeartMate 3 left ventricular assist device— suffered significantly fewer strokes, pump-related blood clots and bleeding episodes after two years, compared with similar patients who received an older, more established pump, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

18 Mar 2019

Team-based approach is key to successful care of pregnant women with heart failure

Any time a pregnant woman presents in heart failure there are risks to both mother and baby. What does it take to protect the mother and her growing baby for the best possible outcome?

18 Mar 2019

Absorbable, antibiotic-eluting envelope can reduce rate of cardiac device infections

A Cleveland Clinic-led research team has found that using an absorbable, antibiotic-eluting envelope when implanting cardiac devices like pacemakers and defibrillators can cut the rate of major infections by 40 percent.

18 Mar 2019

Next-generation LVAD device clinically superior, safer for heart failure patients

The final results are in for MOMENTUM 3, the largest left-ventricular assist device trial ever conducted.

18 Mar 2019

Long-awaited structure offers new insights into rejection of transplanted organs

Rejection of any kind is always hard to deal with, but when one's body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.

15 Mar 2019

Deadly inherited blood disorders cured with bone marrow transplant

Doubling the low amount of total body radiation delivered to patients undergoing bone marrow transplants with donor cells that are only "half-matched" increased the rate of engraftment from only about 50 percent to nearly 100 percent, according to a new study by Johns Hopkins researchers.

15 Mar 2019

Antiviral treatment improves survival for kidney transplant recipients infected with HBV or HCV

Prior to the development of antiviral therapy, kidney transplant recipients infected with either hepatitis B or hepatitis C experienced poor outcomes.

15 Mar 2019

Study shows ability of non-invasive imaging technique to identify small airway damage in COPD

Chronic obstructive pulmonary disease, an inflammatory disease of the small airways in the lungs, affects 16 million Americans and is the fourth leading cause of death in the United States, according to the National Heart Lung and Blood Institute.

14 Mar 2019

Blood-clotting protein may hold the key to liver regeneration, shows study

The liver is the only organ in the body that can regenerate. But some patients who undergo a liver resection, a surgery that removes a diseased portion of the organ, end up needing a transplant because the renewal process doesn't work.

11 Mar 2019

Loss of Medicare coverage associated with kidney transplant outcomes

Kidney transplant recipients under 65 years of age qualify for Medicare coverage following transplantation, but coverage ends after three years. A new American Journal of Transplantation study found that failure of the transplanted kidney was 990 percent to 1630 percent higher for recipients who lost Medicare coverage before this three-year time point compared with recipients who lost Medicare on time.

7 Mar 2019

Patients experiment with prescription drugs to fight aging

Dr. Alan Green's patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

6 Mar 2019

Scientists move one step closer to a HIV cure

Scientists found no rebound of HIV in two patients who stopped taking their HIV medication after they received stem cell transplants for a hematological [blood] disease. Both patients underwent stem cell transplantation as part of their cancer treatment.

6 Mar 2019

Second man cured of HIV

A London is now free of HIV/AIDS after a stem cell transplant therapy. This is the second such case after the first case of cured HIV in Berlin.

5 Mar 2019

Transplant News and Research

World’s first HIV-to-HIV kidney transplant with living donor succeeds

U of G study beginning to unravel mystery of hagfish’s zombie hearts

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

Anti-TB drugs can increase susceptibility to Mtb reinfection

Surprising discovery offers clues to limit graft-vs.-host disease

Study provides new insight into blood cell and immune cell production

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Novel cardiac pump shows superior outcomes in patients with advanced heart failure

Team-based approach is key to successful care of pregnant women with heart failure

Absorbable, antibiotic-eluting envelope can reduce rate of cardiac device infections

Next-generation LVAD device clinically superior, safer for heart failure patients

Long-awaited structure offers new insights into rejection of transplanted organs

Deadly inherited blood disorders cured with bone marrow transplant

Antiviral treatment improves survival for kidney transplant recipients infected with HBV or HCV

Study shows ability of non-invasive imaging technique to identify small airway damage in COPD

Blood-clotting protein may hold the key to liver regeneration, shows study

Loss of Medicare coverage associated with kidney transplant outcomes

Patients experiment with prescription drugs to fight aging

Scientists move one step closer to a HIV cure

Second man cured of HIV

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