Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Discovery of gene that may play a role in centronuclear myopathy

By studying the molecules that regulate the formation of muscle, researchers at UT Southwestern Medical Center have discovered a gene that may play a role in a rare muscular disease in humans.

31 Aug 2005

Danish scientists have identified which head and neck cancer patients will benefit from additional drug treatment during radiotherapy

Tumours that have low concentrations of oxygen (hypoxia) are resistant to radiotherapy. A drug called nimorazole (a hypoxia radiosensitiser) can improve the outcome of radiotherapy for patients with these types of tumours. However, at the moment there is no way to identify people with tumours that lack oxygen, who need this additional drug treatment, from those that only need radiotherapy.

30 Aug 2005

Toxicity from chemotherapy in lung cancer patients could help predict treatment efficacy

Chemotherapy is standard treatment for patients with advanced non-small cell lung cancer, although benefits are modest and toxicity substantial. Massimo Di Maio and colleagues hypothesised that neutropenia, a haematological toxicity, could be a predictor of drug activity and treatment efficacy.

30 Aug 2005

Before hitting the beach, learn the signs of skin cancer

With summer coming to a close, the American Society for Therapeutic Radiology and Oncology has published a new brochure to help the public understand the signs and symptoms of skin cancer as well as learn the treatment options for the disease.

29 Aug 2005

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Research published by the University of Helsinki, Finland, indicates that cytostatic and radiation therapies administered before stem cell transplantation often damage children's permanent teeth.

29 Aug 2005

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

The phase I clinical study will enroll 20 patients with advanced solid cancers (including most common tumor types), and is the culmination of more than a decade of work by a team of researchers led by Professor Esther H. Chang, Ph.D. at the Lombardi Comprehensive Cancer Center.

25 Aug 2005

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

EntreMed a clinical-stage pharmaceutical company developing therapeutics primarily for the treatment of cancer and inflammatory diseases, has announced the presentation of positive preclinical results for its lead compound, 2-methoxyestradiol (2ME2), in models of rheumatoid arthritis.

24 Aug 2005

Unique blood test detects iron deficiency in infants earlier

A unique blood test detects iron deficiency in infants earlier and more accurately than the commonly used hemoglobin screening test, according to a study in the August 24/31 issue of the Journal of the American Medical Association.

23 Aug 2005

Sentinel node biopsy, when performed before chemotherapy to shrink the tumor, is very reliable

New breast cancer research shows for the first time that even women with large breast tumors can benefit from a less invasive biopsy method that has been reserved until now for women with small breast cancers.

23 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Women think very rationally about breast cancer surgery from their own perspectives

When a woman is diagnosed with breast cancer, her top priority is to get the cancer out and reduce the odds that it will ever return. But for some women just getting the cancer out doesn't feel like enough.

22 Aug 2005

Young breast cancer sufferers need more fertility advice before treatment

According to new research led by the University of New South Wales (UNSW), Australia, 25% of young breast cancer sufferers say that there was no discussion of fertility issues at the time of diagnosis, despite the possibility of infertility after treatment.

22 Aug 2005

Nearly one-third of former brain tumor patients require special education services

Children who survive brain cancer struggle for years with the malevolent echo of the disease and its treatment, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital.

22 Aug 2005

Medulloblastoma irradiation may impair reading skills in young children

Irradiation therapy for the brain cancer medulloblastoma is more likely to impair IQ and reading skills of younger children than older children even if the dose of radiation is reduced, according to the results of the largest study of its kind, conducted by investigators at St. Jude Children's Research Hospital, Texas Children's Cancer Center (Houston) and Royal Children's Hospital (Melbourne, Australia).

22 Aug 2005

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

A new study finds many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals, and says investigators should be committed not just to finding novel compounds, but also to make sure final results of their studies be disseminated to the medical community.

22 Aug 2005

Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Cancer Research Technology licenses novel cancer diagnostic markers

Cancer Research Technology Limited announced today that they have entered into a worldwide license agreement with TriPath Imaging, Inc.

22 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Interventions give cancer survivors a greater feeling of control over their health and emotional well-being

Women who receive an educational or nutritional intervention following the completion of their treatment for breast cancer are less likely to be depressed and have a better quality of life than other breast cancer survivors, according to a study by researchers at Carnegie Mellon University, the University of Pittsburgh Medical Center and Emory University.

16 Aug 2005

People who drink alcohol have a lower risk of non-Hodgkin's lymphoma

People who drink alcohol have a lower risk of non-Hodgkin's lymphoma (NHL) than non-drinkers, researchers at Yale's Department of Epidemiology and Public Health (EPH) write in an article published in Lancet Oncology.

15 Aug 2005

Oncology News and Research

Further Reading

Discovery of gene that may play a role in centronuclear myopathy

Danish scientists have identified which head and neck cancer patients will benefit from additional drug treatment during radiotherapy

Toxicity from chemotherapy in lung cancer patients could help predict treatment efficacy

Before hitting the beach, learn the signs of skin cancer

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

Unique blood test detects iron deficiency in infants earlier

Sentinel node biopsy, when performed before chemotherapy to shrink the tumor, is very reliable

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

Women think very rationally about breast cancer surgery from their own perspectives

Young breast cancer sufferers need more fertility advice before treatment

Nearly one-third of former brain tumor patients require special education services

Medulloblastoma irradiation may impair reading skills in young children

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

Phase I cancer findings under-reported

Cancer Research Technology licenses novel cancer diagnostic markers

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Interventions give cancer survivors a greater feeling of control over their health and emotional well-being

People who drink alcohol have a lower risk of non-Hodgkin's lymphoma

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